An enzyme that has lost its shape a. is denatured and no longer functional. b. is denatured but still functional. c. is not different from a regular enzyme as shape is not important. d. can be restored by extreme temperatures or pH swings. Predict whether each of the following has ionic, polar covalent, or not O_2 Solution 7) Each enzyme has specific active sites. When an enzyme loses its shape then its active sites are no longer functional. As a result, the properties of the enzyme are destroyed. This process is called denaturation. Therefore, an enzyme that has lost its shape is denatured and no longer functional. (Answer) (a) 8) In oxygen molecule (O2), two oxygen atoms are joined by double covalent bond. The bonds are formed by sharing of electron pairs. The electron pairs are equally shared between two oxygen atoms. For this reason, oxygen molecule has non-polar covalent bonds..