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THE LYMPHATIC SYSTEM
Learning Strand 2
Michael Cachero Gelacio / Teacher III – District I ALS Coordinator
Read the following story:
Ben was a twelve-year old boy who liked to
play a lot. He loved to roll in the mud with his
playmates and he often swam in the river that
ran through his town. One day, he felt sick. He
was running a high fever and he could hardly
move. His mother took him to a doctor who said
that he should be confined in a hospital. In the
hospital, a doctor gave Ben some medicine to
make him well.
After a few days, Ben was up and about
again. When his doctor saw him, the doctor
smiled and said, “It’s a good thing Ben’s immune
system is strong. He would have been worse if
his immune system didn’t help him fight the
disease.”
THE LYMPHATIC SYSTEM is a
network of vessels whose primary
function is to (1) assist in
circulating body fluids.
These vessels transport excess
fluid away from the INTERSTITIAL
SPACES (spaces between cells in
body tissues) and return it to the
bloodstream. This prevents tissues
from swelling up.
(2) The lymphatic system also
filters out disease - causing
organisms, produces a type of
white blood cells and generates
antibodies.
1. When blood reaches the cells,
exchange of food, oxygen and
nutrients takes place.
2. LYMPHATIC VESSELS collects
and stores the liquid from the
plasma that leaks from the
capillary wall.
3. LYMPH name of the liquid inside
the lymphatic vessel. Lymph is a
milky fluid that continuously bathes
the cells of the body.
Lymph is found all over the body except
the central nervous system, eyeballs, inner
ear, cartilage and the epidermis of the skin.
Lymph has components similar to those of
blood, except that is has no red blood cells
and platelets. It has a type of white blood
cells called LYMPHOCYTES as well as
cells that engulf foreign materials, which
are called MACROPHAGES.
PARTS OF THELYMPHATIC SYSTEM
1. Lymphatic vessels - are tubes through
which lymph passes as it circulates the
body. They return the lymph to the
blood through veins near the heart.
There are two major lymphatic vessels.
a. THORACIC DUCT - place where
all the lymph collected from the left
side of the body, the digestive tract
and the right side of the lower part
of the body flows into the thoracic
duct. The thoracic duct then
empties the lymph into the left
subclavian vein, which then brings
the lymph to the heart.
b. RIGHT LYMPHATIC DUCT - place
where all the lymph from the right
side of the head, neck and chest
go which then deposits it into the
right subclavian vein.
PARTS OF THELYMPHATIC SYSTEM
2. Lymph nodes - These are clumps of
tissue that are found mainly in the neck,
groin and armpits. The primary function
of the lymph nodes is to produce
lymphocytes.
PARTS OF THELYMPHATIC SYSTEM
3. Lymphoid organs - These are organs
that contain a large amount of
lymphocytes. Among these are the:
a. Spleen - a soft, purplish organ
lying high above the abdomen.
This organ receives blood from an
artery that branches off to the
aorta, the largest artery in the
body. The blood vessels of the
spleen are surrounded by
lymphocytes and macrophages.
The macrophages remove harmful
microorganisms from the blood and
destroy them by phagocytosis.
PARTS OF THELYMPHATIC SYSTEM
b. Tonsils - masses of tissue located
in a protective ring under mucous
membranes in the mouth and back
of the throat. These help protect
the body against bacteria that
invade tissues around the
openings of the mouth and nose.
PARTS OF THELYMPHATIC SYSTEM
c. Thymus - a soft, flattened, pinkish-
gray organ located in the upper
chest under the breastbone.
The thymus serves as a site for the
development of lymphocytes in the
fetus. Soon after birth, the thymus
begins secreting a group of
hormones that enable lymphocytes
to develop into T cells, groups of
cells that protect the body against
invasions by foreign organisms.
If the thymus fails to develop, the
immune system cannot develop
completely as well.
SIMILARITIES DIFFERENCES
They both circulate fluids throughout
the body.
The ciculatory system circulates blood
while the lymphatic system circulates
lymph.
Blood circulates through the pumping
action of the heart; lymph circulates
without any organ to pump it.
Both circulating fluids pass through a
series of tubes.
Blood passes through veins, arteries,
and capillaries: lymph passes through
lymphatic vessels.
FUNCTIONS
The lymphatic system has two main functions:
1. Maintaining fluid balance in the body
Drainage of the lymph is important,
because if the fluid accumulates in the
interstitial spaces over a period of time,
the tissues would swell up. This could lead
to the destruction of the tissues.
FUNCTIONS
2. Immunity
The lymph nodes filter the air that passes
through the mouth and the spleen filters the blood
that passes through it.
The lymph nodes, tonsils and spleen
accomplish their tasks by trapping and destroying
antigens in the lymph, air and blood, respectively.
Antigens are molecules that cause the body to
produce antibodies, which are proteins. Bacteria,
viruses, malignant (cancer-causing) cells and
foreign tissues are examples of antigens.
FUNCTIONS
LYMPHOCYTES destroys antigen. Lymphocytes
are a group of white blood cells.
There are two types of lymphocytes that are active
in the immunity function of the lymphatic system.
The T lymphocytes (T cells) and B lymphocytes
(B cells).
B lymphocytes produce antibodies.
Antibodies are able to recognize
specific antigens and attach
themselves to these antigens. This
action causes the antigens to become
inactive and prevents them from
harming the cells of the body.
T lymphocytes are further divided into
groups, each having a specific function.
1. When these cells recognize foreign
antigens on the surface of a body,
they change into active cells that
attack the infected cells directly.
2. Some T cells also release chemicals
that draw the macrophages, which
then engulf and absorb the infected
cells.
THE LYMPHATIC SYSTEM
DISEASES THAT AFFECT
a. As of 1999, there were already 23,000 Filipinos 15 to 49 years old who
were infected with HIV. Still, a lot of us remain ignorant of the causes and
effects of this virus and the disease it brings - AIDS.
• According to PH DOH 7,363 HIV cases have been recorded in the first
eight months of 2017, including 891 AIDS cases and 334 deaths.
• Purportedly there are 46,985 HIV cases recorded nationwide since
1984. The figure includes 4,556 AIDS cases and 2,303 deaths. These are
the small percentile of reported cases. Millions of Filipinos never in their
lives see a doctor or a nurse.
• Republic Act No. 8504, otherwise known as The Philippine Aids
Prevention And Control Act Of 1998.
Distinguishthe correct statementsfrom the incorrect
ones
1. You can get HIV in swimming pools.
2. If you are infected with HIV, you will surely get sick with AIDS.
3. HIV-positive women can infect their babies through breastfeeding.
4. If you hug someone who has HIV or AIDS, you will also get infected.
5. You can get HIV from mosquito and animal bites.
6. AIDS is a disease that attacks the immune system.
7. So far, no cure for AIDS has been discovered.
8. AIDS stands for acquired immune deficiency syndrome.
9. You can get infected with HIV through unprotected sex, sharing needles
and blood transfusion.
10.You can get infected with HIV if you share food and personal things with an
HIV-infected person.
1. AIDS is a specific group of diseases that result from the
reduction of the immunity of the body. This means that it attacks
the lymphatic system, specifically, the T lymphocytes or T cells.
This is brought on by a virus called HUMAN
IMMUNODEFICIENCY VIRUS (HIV).
2. Medical experts call the “HEALTH THREAT OF THE
CENTURY.”
HIV is transmitted through the following means:
o Unprotected sex with an infected person
o Sharing needles or syringes for drug injection
with someone who is infected with the virus
o Transfusion of infected blood
However, women infected with HIV can pass
on the virus to their unborn children. They can
also transmit the virus to their babies through
breastfeeding. Hence, if a woman is HIV-
positive (infected with HIV), she is
discouraged from getting pregnant.
1. Not all infected people with HIV, will develop AIDS, but
it is highly probable that he or she will.
2. A person has an AIDS if their T cell count becomes
lower than 200 cells per cubic millilitre of blood and
they develop an infection.
1. AIDS causes death because as HIV
multiplies inside the body, it attacks
and kills the T cells. This slows down
the ability of the body to fight infection
caused by bacteria, viruses and other
foreign materials. Thus, the patient
becomes prone to all sorts of
infections, and these infections are
the ones that eventually lead to the
patient’s death.
 Among these infections are
pneumonia,
 Kaposi’s sarcoma (a type of skin
cancer), and
 meningitis (an infection of the
fluids in the brain).
 Without the T cells to fight the
organisms that cause the
infection, the infection worsens
until the patient dies.
EDEMA
A swelling on the body caused by the
accumulation of fluid in the body tissues.
It results from the inability of the
lymphatic system to perform the task of
draining the body’s fluids.
It can also be brought on by various
diseases and disorders, such as heart
failure, kidney malfunction and varicose
veins.
Lymphangitis
The inflammation of the lymphatic
vessels that results from infection by
streptococci and staphylococci, two
common bacteria.
These bacteria are usually transmitted
through insect or animal bites.
Lymphangitis and lymphadenitis are complications that result from infections
caused by bacteria.
Lymphadenitis
Involves inflammation of the lymph
nodes.
This may occur if the nodes are
overwhelmed by bacteria, viruses, fungi
or other organisms, infection then
develops within the nodes.
LYMPHOMA
A cancer of the lymphatic system. The
most common type of lymphoma is non-
Hodgkins lymphoma.
In this type of disease, cells in the
lymphatic system become abnormal.
They divide and grow without any order
or control. This disease can start
anywhere in the body.
Its most common symptom is a painless
swelling of the lymph nodes in the neck,
under arm or groin. Lymphoma patients
usually undergo chemotherapy and
radiation therapy. Some even have to
undergo surgery.
BIOPSY involves getting a tissue sample and studying it under a
microscope.
ELEPHANTIASIS
An abnormal enlargement of any part of
the body caused by the obstruction of
the lymphatic vessels in the affected
area. This disease commonly affects the
leg and scrotum.
In tropical countries like ours,
elephantiasis is normally caused by
FILARIASIS, an infestation of certain
parasitic round worms called
WUCHERERIA BANCROFTI. These
tiny worms are introduced into the body
by many types of mosquitoes. These
parasites search out the lymph nodes
and lymph vessels, where they absorb
nutrients.

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LS 2 9 The Lymphatic System

  • 1. THE LYMPHATIC SYSTEM Learning Strand 2 Michael Cachero Gelacio / Teacher III – District I ALS Coordinator
  • 2.
  • 3.
  • 4.
  • 5. Read the following story: Ben was a twelve-year old boy who liked to play a lot. He loved to roll in the mud with his playmates and he often swam in the river that ran through his town. One day, he felt sick. He was running a high fever and he could hardly move. His mother took him to a doctor who said that he should be confined in a hospital. In the hospital, a doctor gave Ben some medicine to make him well. After a few days, Ben was up and about again. When his doctor saw him, the doctor smiled and said, “It’s a good thing Ben’s immune system is strong. He would have been worse if his immune system didn’t help him fight the disease.”
  • 6. THE LYMPHATIC SYSTEM is a network of vessels whose primary function is to (1) assist in circulating body fluids. These vessels transport excess fluid away from the INTERSTITIAL SPACES (spaces between cells in body tissues) and return it to the bloodstream. This prevents tissues from swelling up. (2) The lymphatic system also filters out disease - causing organisms, produces a type of white blood cells and generates antibodies.
  • 7. 1. When blood reaches the cells, exchange of food, oxygen and nutrients takes place. 2. LYMPHATIC VESSELS collects and stores the liquid from the plasma that leaks from the capillary wall. 3. LYMPH name of the liquid inside the lymphatic vessel. Lymph is a milky fluid that continuously bathes the cells of the body.
  • 8. Lymph is found all over the body except the central nervous system, eyeballs, inner ear, cartilage and the epidermis of the skin. Lymph has components similar to those of blood, except that is has no red blood cells and platelets. It has a type of white blood cells called LYMPHOCYTES as well as cells that engulf foreign materials, which are called MACROPHAGES.
  • 9.
  • 10. PARTS OF THELYMPHATIC SYSTEM 1. Lymphatic vessels - are tubes through which lymph passes as it circulates the body. They return the lymph to the blood through veins near the heart. There are two major lymphatic vessels. a. THORACIC DUCT - place where all the lymph collected from the left side of the body, the digestive tract and the right side of the lower part of the body flows into the thoracic duct. The thoracic duct then empties the lymph into the left subclavian vein, which then brings the lymph to the heart. b. RIGHT LYMPHATIC DUCT - place where all the lymph from the right side of the head, neck and chest go which then deposits it into the right subclavian vein.
  • 11. PARTS OF THELYMPHATIC SYSTEM 2. Lymph nodes - These are clumps of tissue that are found mainly in the neck, groin and armpits. The primary function of the lymph nodes is to produce lymphocytes.
  • 12. PARTS OF THELYMPHATIC SYSTEM 3. Lymphoid organs - These are organs that contain a large amount of lymphocytes. Among these are the: a. Spleen - a soft, purplish organ lying high above the abdomen. This organ receives blood from an artery that branches off to the aorta, the largest artery in the body. The blood vessels of the spleen are surrounded by lymphocytes and macrophages. The macrophages remove harmful microorganisms from the blood and destroy them by phagocytosis.
  • 13. PARTS OF THELYMPHATIC SYSTEM b. Tonsils - masses of tissue located in a protective ring under mucous membranes in the mouth and back of the throat. These help protect the body against bacteria that invade tissues around the openings of the mouth and nose.
  • 14. PARTS OF THELYMPHATIC SYSTEM c. Thymus - a soft, flattened, pinkish- gray organ located in the upper chest under the breastbone. The thymus serves as a site for the development of lymphocytes in the fetus. Soon after birth, the thymus begins secreting a group of hormones that enable lymphocytes to develop into T cells, groups of cells that protect the body against invasions by foreign organisms. If the thymus fails to develop, the immune system cannot develop completely as well.
  • 15. SIMILARITIES DIFFERENCES They both circulate fluids throughout the body. The ciculatory system circulates blood while the lymphatic system circulates lymph. Blood circulates through the pumping action of the heart; lymph circulates without any organ to pump it. Both circulating fluids pass through a series of tubes. Blood passes through veins, arteries, and capillaries: lymph passes through lymphatic vessels.
  • 16. FUNCTIONS The lymphatic system has two main functions: 1. Maintaining fluid balance in the body Drainage of the lymph is important, because if the fluid accumulates in the interstitial spaces over a period of time, the tissues would swell up. This could lead to the destruction of the tissues.
  • 17. FUNCTIONS 2. Immunity The lymph nodes filter the air that passes through the mouth and the spleen filters the blood that passes through it. The lymph nodes, tonsils and spleen accomplish their tasks by trapping and destroying antigens in the lymph, air and blood, respectively. Antigens are molecules that cause the body to produce antibodies, which are proteins. Bacteria, viruses, malignant (cancer-causing) cells and foreign tissues are examples of antigens.
  • 18. FUNCTIONS LYMPHOCYTES destroys antigen. Lymphocytes are a group of white blood cells. There are two types of lymphocytes that are active in the immunity function of the lymphatic system. The T lymphocytes (T cells) and B lymphocytes (B cells).
  • 19. B lymphocytes produce antibodies. Antibodies are able to recognize specific antigens and attach themselves to these antigens. This action causes the antigens to become inactive and prevents them from harming the cells of the body.
  • 20. T lymphocytes are further divided into groups, each having a specific function. 1. When these cells recognize foreign antigens on the surface of a body, they change into active cells that attack the infected cells directly. 2. Some T cells also release chemicals that draw the macrophages, which then engulf and absorb the infected cells.
  • 21.
  • 23. a. As of 1999, there were already 23,000 Filipinos 15 to 49 years old who were infected with HIV. Still, a lot of us remain ignorant of the causes and effects of this virus and the disease it brings - AIDS. • According to PH DOH 7,363 HIV cases have been recorded in the first eight months of 2017, including 891 AIDS cases and 334 deaths. • Purportedly there are 46,985 HIV cases recorded nationwide since 1984. The figure includes 4,556 AIDS cases and 2,303 deaths. These are the small percentile of reported cases. Millions of Filipinos never in their lives see a doctor or a nurse. • Republic Act No. 8504, otherwise known as The Philippine Aids Prevention And Control Act Of 1998.
  • 24. Distinguishthe correct statementsfrom the incorrect ones 1. You can get HIV in swimming pools. 2. If you are infected with HIV, you will surely get sick with AIDS. 3. HIV-positive women can infect their babies through breastfeeding. 4. If you hug someone who has HIV or AIDS, you will also get infected. 5. You can get HIV from mosquito and animal bites. 6. AIDS is a disease that attacks the immune system. 7. So far, no cure for AIDS has been discovered. 8. AIDS stands for acquired immune deficiency syndrome. 9. You can get infected with HIV through unprotected sex, sharing needles and blood transfusion. 10.You can get infected with HIV if you share food and personal things with an HIV-infected person.
  • 25. 1. AIDS is a specific group of diseases that result from the reduction of the immunity of the body. This means that it attacks the lymphatic system, specifically, the T lymphocytes or T cells. This is brought on by a virus called HUMAN IMMUNODEFICIENCY VIRUS (HIV). 2. Medical experts call the “HEALTH THREAT OF THE CENTURY.”
  • 26. HIV is transmitted through the following means: o Unprotected sex with an infected person o Sharing needles or syringes for drug injection with someone who is infected with the virus o Transfusion of infected blood However, women infected with HIV can pass on the virus to their unborn children. They can also transmit the virus to their babies through breastfeeding. Hence, if a woman is HIV- positive (infected with HIV), she is discouraged from getting pregnant.
  • 27. 1. Not all infected people with HIV, will develop AIDS, but it is highly probable that he or she will. 2. A person has an AIDS if their T cell count becomes lower than 200 cells per cubic millilitre of blood and they develop an infection.
  • 28. 1. AIDS causes death because as HIV multiplies inside the body, it attacks and kills the T cells. This slows down the ability of the body to fight infection caused by bacteria, viruses and other foreign materials. Thus, the patient becomes prone to all sorts of infections, and these infections are the ones that eventually lead to the patient’s death.  Among these infections are pneumonia,  Kaposi’s sarcoma (a type of skin cancer), and  meningitis (an infection of the fluids in the brain).  Without the T cells to fight the organisms that cause the infection, the infection worsens until the patient dies.
  • 29. EDEMA A swelling on the body caused by the accumulation of fluid in the body tissues. It results from the inability of the lymphatic system to perform the task of draining the body’s fluids. It can also be brought on by various diseases and disorders, such as heart failure, kidney malfunction and varicose veins.
  • 30. Lymphangitis The inflammation of the lymphatic vessels that results from infection by streptococci and staphylococci, two common bacteria. These bacteria are usually transmitted through insect or animal bites. Lymphangitis and lymphadenitis are complications that result from infections caused by bacteria.
  • 31. Lymphadenitis Involves inflammation of the lymph nodes. This may occur if the nodes are overwhelmed by bacteria, viruses, fungi or other organisms, infection then develops within the nodes.
  • 32. LYMPHOMA A cancer of the lymphatic system. The most common type of lymphoma is non- Hodgkins lymphoma. In this type of disease, cells in the lymphatic system become abnormal. They divide and grow without any order or control. This disease can start anywhere in the body. Its most common symptom is a painless swelling of the lymph nodes in the neck, under arm or groin. Lymphoma patients usually undergo chemotherapy and radiation therapy. Some even have to undergo surgery. BIOPSY involves getting a tissue sample and studying it under a microscope.
  • 33. ELEPHANTIASIS An abnormal enlargement of any part of the body caused by the obstruction of the lymphatic vessels in the affected area. This disease commonly affects the leg and scrotum. In tropical countries like ours, elephantiasis is normally caused by FILARIASIS, an infestation of certain parasitic round worms called WUCHERERIA BANCROFTI. These tiny worms are introduced into the body by many types of mosquitoes. These parasites search out the lymph nodes and lymph vessels, where they absorb nutrients.

Editor's Notes

  1. If you’re the last person to leave your house, what are the things you do? Do you lock the doors? Do you check if the windows are closed, the lights are turned off and the gas tank is sealed? These habits manifest your need for security. If you accidentally leave your door unlocked, what could possibly happen?
  2. Life nowadays is full of uncertainties. Every day, you face danger from sickness, accidents and other events that threaten your well-being and health. You know how important security is in your life. You lock the doors of your house before you leave because you don’t want intruders to get in. There are always bad people who can harm your family and damage your property.
  3. You are fortunate to have a built-in security system inside your body. This is the immune or lymphatic system, which maintains the immunity of your body. The lymphatic system keeps you safe from harmful organisms that can make you sick. It works as your own “army” to defend your body from harm. But do you know what exactly make up your lymphatic system and how it works?
  4. The lymphatic system keeps the body immune to infections, enabling it to fight off organisms that can harm the body. Indeed, the lymphatic system is a very important part of the body. Without it, staying healthy would not be possible.
  5. QUESTIONS: Why do you think Ben got sick? How do you think Ben was able to recover from his illness?
  6. The picture above shows a capillary network through which blood passes and reaches the cells of the body. When blood reaches the cells, exchange of food, oxygen and nutrients takes place. As this occurs, a little liquid from the plasma (the liquid part of blood) leaks out of the capillary wall. This liquid reaches the spaces between the body cells (interstitial spaces) and is collected by and stored in tubes called lymphatic vessels. Once inside the lymphatic vessel, the liquid is called lymph. Lymph is a milky fluid that continuously bathes the cells of the body. Wherever there are cells, lymph is also found. It needs to be circulated like blood in order to remove excess fluid and harmful materials from interstitial spaces.
  7. Lymph is found all over the body except the central nervous system, eyeballs, inner ear, cartilage and the epidermis of the skin. The walls of lymph vessels are lined with a single layer of endothelium which permits fluid and large particles, such as plasma proteins and foreign substances, to enter. Lymph has components similar to those of blood, except that is has no red blood cells and platelets. It has a type of white blood cells called lymphocytes as well as cells that engulf foreign materials, which are called macrophages.
  8. These are the thoracic duct and right lymph duct. All the lymph collected from the left side of the body, the digestive tract and the right side of the lower part of the body flows into the thoracic duct. The thoracic duct then empties the lymph into the left subclavian vein, which then brings the lymph to the heart. On the other hand, all the lymph from the right side of the head, neck and chest go to the right lymph duct which then deposits it into the right subclavian vein.
  9. Lymph nodes – These are clumps of tissue that are found mainly in the neck, groin and armpits. However, they are found all over the lymphatic vessels. Lymph passes through the lymph nodes before it returns to the blood. The primary function of the lymph nodes is to produce lymphocytes.
  10. It is said that the circulatory and lymphatic systems are similar. Can you identify the similarities and differences between these two organ systems? List them in the table
  11. Maintaining fluid balance in the body is accomplished by the lymphatic vessels, which collect lymph from the interstitial spaces and return it to the blood. Drainage of the lymph is important, because if the fluid accumulates in the interstitial spaces over a period of time, the tissues would swell up. This could lead to the destruction of the tissues.
  12. Immunity or the ability of the body to fight off infection is accomplished by the lymphatic system through the actions of its components.
  13. Palpate for your lymph nodes. Feel the lymph nodes in your body by gently pressing your hand against your armpits, groin or neck. If you weren’t able to feel any tiny lumps, that means you are not suffering from any infection. You can actually see your lymphatic system at work when you are sick. When you are sick, you will notice that you have some lumps in your neck. These lumps are swollen lymph nodes that are helping you get well. Your lymph nodes swell because your lymphatic vessels are carrying the infection there so that your lymphocytes can act on it immediately.
  14. If you’re the last person to leave your house, what are the things you do? Do you lock the doors? Do you check if the windows are closed, the lights are turned off and the gas tank is sealed? These habits manifest your need for security. If you accidentally leave your door unlocked, what could possibly happen?
  15. In this lesson, you will learn about some diseases that can affect the lymphatic system. Ironic as it may seem, the primary organ system that defends the body from harm is also prone to diseases. Hence, it is important to know what these diseases are.
  16. If a person is infected with HIV, this does not mean that he or she will develop AIDS, but it is highly probable that he or she will. Some HIV-positive people can go for more than ten years without developing AIDS. However, once their T cell count becomes lower than 200 cells per cubic millilitre of blood and they develop an infection, they are considered to have AIDS already.
  17. If a person is infected with HIV, this does not mean that he or she will develop AIDS, but it is highly probable that he or she will. Some HIV-positive people can go for more than ten years without developing AIDS. However, once their T cell count becomes lower than 200 cells per cubic millilitre of blood and they develop an infection, they are considered to have AIDS already.
  18. Both lymphangitis and lymphadenitis should be treated immediately (usually with antibiotics). Otherwise, the infection could spread to the bloodstream and cause death.