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Regulation of Respiration
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Overview
C o n t r o l o f r e s p i r a t i o n
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Regulation of
respiration
Nervous
regulatory
mechanism
Automatic
control
Medulla
DRG
VRG
Pons
Apneustic
center (lower
pons)
Pneumotaxic
center (upper
pons)
Voluntary
control
Chemical
regulatory
mechanism
Peripheral
chemoreceptor
Medullary
chemoreceptor
Pulmonary and
myocardial
chemoreceptor
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1. Neural Regulation
2. Chemical Regulation
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Respiratory control system
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Medulla
C3
C4
C5
Phrenic nerve
Pons Pnemotaxic
Co2
O2
[Hx]
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Reaction
Co2 + H2O H2Co3 H+ + HCo3-
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Chemoreceptors
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• They are the receptors which give response to change in chemical
constituents in the blood like increased hydrogen ion
concentration(decreased pH).
• They are classified into two groups:
1)Central chemoreceptors
2)Peripheral chemoreceptors
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Central chemoreceptors Peripheral chemoreceptors
• Present in Brain.
• Situated in the medulla oblongata.
• Very sensitive to increase in hydrogen ion
concentration [H+].
• WHY IS IT IMPORTANT?
• Present in the peripheral portions of the body.
• Very sensitive to partial pressure of oxygen.
• WHY IS IT IMPORTANT?