Majority of THPs had limited knowledge of the causes of hypertension, though some mentioned stress, diet, and spiritual factors. Divination was the preferred method of diagnosis for half of the THPs. Most THPs described common risk factors and complications of hypertension. All THPs used indigenous herbal remedies to treat hypertension, consisting of mixtures of various plants and plant parts. THPs determined treatment effectiveness primarily through patient feedback and physical appearance improvement, with some relying on spiritual means or diuresis.
Un estudio sobre las caracteristicas del tratamiento sde la TB XDR en sudafrica y el pronostico de vida de los pacientes segun las estrategias terapeuticas
Hepatitis C Risk Assessment, Testing and Referral for Treatment in primary Ca...Real Wellness, LLC
Dr. Robert Winn worked with a team to determine rates of hepatitis C (HCV) risk factor ascertainment, testing, and referral in urban primary care practices, with particular attention to the effect of race and ethnicity.
A study on clinical presentation and various risk factors associated with pht...IjcmsdrJournal
Background: Tuberculosis is one of the most ancient infectious diseases caused by Mycobacterium tuberculosis. The population most affected is the young and economically productive one. The social factors include poor quality of life, poor housing, overcrowding, population explosion, under nutrition, lack of education, and last but not the least lack of awareness of cause of illness.
Aims and Objectives:
1. To study the clinical presentation of tuberculosis in patients.
2. To study various risk factors of tuberculosis.
Material and Methods: This study was conducted at selected designated microscopic centre (DMCs) Kanpur Nagar district has a population of 45.73lakh ( Census 2011).All the patients who were registered in the selected DMCs in the last one month of the year 2016 ( between April and May) were taken into consideration for the present study. Data was collected on predesigned and pretested questionnaire using direct personal interview method of patients at DMCs on the DOTS days of the week i.e Monday, Wednesday and Friday. Informed consent of the study subjects was taken before interview. A total of 105 registered patients were interviewed personally and also the treatment card of patients was obtained from their respective DMCs.
Results: Out of 105 cases of tuberculosis which reported at DMCs maximum no. of patients belongs to age group between 21-40 yrs of age group (58%). Majority of cases were married (65.7%) cases. (62%) cases were Hindu by religion and (58%) belongs to other backward caste. In the study we found majority of patient was illiterate (34.3%). Most common clinical presentation was cough, fever and cough with expectoration, anorexia was reported in (61.9 %) of cases (77%) were cigarette/bidi smokers, 60% were tobacco chewer. Diabetes was reported in (12.4%) cases and (3.8%) cases were HIV positive.
Seroepidemiology of Toxoplasma gondii infection in drivers involved in road t...Erwin Chiquete, MD, PhD
Background: The prevalence of toxoplasmosis in the general population of Guadalajara, Mexico, is around 32%.
Toxoplasmosis can cause ocular lesions and slowing of reaction reflexes. Latent toxoplasmosis has been related
with traffic accidents. We aimed to assess the prevalence of anti-Toxoplasma gondii antibodies and visual
impairments related with traffic accidents in drivers from the metropolitan Guadalajara.
Methods: We prospectively evaluated the prevalence of IgG and IgM anti-T. gondii antibodies in 159 individuals
involved in traffic accidents, and in 164 control drivers never involved in accidents. Cases of toxoplasmosis
reactivation or acute infection were detected by PCR in a subset of 71 drivers studied for the presence of T. gondii
DNA in blood samples. Ophthalmologic examinations were performed in drivers with IgG anti-T. gondii antibodies
in search of ocular toxoplasmosis.
Results: Fifty-four (34%) traffic accident drivers and 59 (36%) controls were positive to IgG anti-T. gondii antibodies
(p = 0.70). Among the 113 seropositive participants, mean anti-T. gondii IgG antibodies titers were higher in traffic
accident drivers than in controls (237.9 ± 308.5 IU/ml vs. 122.9 ± 112.7 IU/ml, respectively; p = 0.01 by Student’s t
test, p = 0.037 by Mann–Whitney U test). In multivariate analyses, anti-T. gondii IgG antibody titers were consistently
associated with an increased risk of traffic accidents, whereas age showed an inverse association. The presence of
IgM-anti-T. gondii antibodies was found in three (1.9%) subjects among traffic accident drives, and in two (1.2%)
controls. Three (4.2%) samples were positive for the presence of T. gondii DNA, all among seropositive individuals.
No signs of ocular toxoplasmosis were found in the entire cohort. Moreover, no other ocular conditions were found
to be associated with the risk of traffic accidents in a multivariate analysis.
Conclusions: Anti-T. gondii antibody titers are associated with the risk of traffic accidents. We could not determine
any association of ocular toxoplasmosis with traffic accidents. Our results warrant further analyses in order to clarify
the link between toxoplasmosis and traffic accidents.
Un estudio sobre las caracteristicas del tratamiento sde la TB XDR en sudafrica y el pronostico de vida de los pacientes segun las estrategias terapeuticas
Hepatitis C Risk Assessment, Testing and Referral for Treatment in primary Ca...Real Wellness, LLC
Dr. Robert Winn worked with a team to determine rates of hepatitis C (HCV) risk factor ascertainment, testing, and referral in urban primary care practices, with particular attention to the effect of race and ethnicity.
A study on clinical presentation and various risk factors associated with pht...IjcmsdrJournal
Background: Tuberculosis is one of the most ancient infectious diseases caused by Mycobacterium tuberculosis. The population most affected is the young and economically productive one. The social factors include poor quality of life, poor housing, overcrowding, population explosion, under nutrition, lack of education, and last but not the least lack of awareness of cause of illness.
Aims and Objectives:
1. To study the clinical presentation of tuberculosis in patients.
2. To study various risk factors of tuberculosis.
Material and Methods: This study was conducted at selected designated microscopic centre (DMCs) Kanpur Nagar district has a population of 45.73lakh ( Census 2011).All the patients who were registered in the selected DMCs in the last one month of the year 2016 ( between April and May) were taken into consideration for the present study. Data was collected on predesigned and pretested questionnaire using direct personal interview method of patients at DMCs on the DOTS days of the week i.e Monday, Wednesday and Friday. Informed consent of the study subjects was taken before interview. A total of 105 registered patients were interviewed personally and also the treatment card of patients was obtained from their respective DMCs.
Results: Out of 105 cases of tuberculosis which reported at DMCs maximum no. of patients belongs to age group between 21-40 yrs of age group (58%). Majority of cases were married (65.7%) cases. (62%) cases were Hindu by religion and (58%) belongs to other backward caste. In the study we found majority of patient was illiterate (34.3%). Most common clinical presentation was cough, fever and cough with expectoration, anorexia was reported in (61.9 %) of cases (77%) were cigarette/bidi smokers, 60% were tobacco chewer. Diabetes was reported in (12.4%) cases and (3.8%) cases were HIV positive.
Seroepidemiology of Toxoplasma gondii infection in drivers involved in road t...Erwin Chiquete, MD, PhD
Background: The prevalence of toxoplasmosis in the general population of Guadalajara, Mexico, is around 32%.
Toxoplasmosis can cause ocular lesions and slowing of reaction reflexes. Latent toxoplasmosis has been related
with traffic accidents. We aimed to assess the prevalence of anti-Toxoplasma gondii antibodies and visual
impairments related with traffic accidents in drivers from the metropolitan Guadalajara.
Methods: We prospectively evaluated the prevalence of IgG and IgM anti-T. gondii antibodies in 159 individuals
involved in traffic accidents, and in 164 control drivers never involved in accidents. Cases of toxoplasmosis
reactivation or acute infection were detected by PCR in a subset of 71 drivers studied for the presence of T. gondii
DNA in blood samples. Ophthalmologic examinations were performed in drivers with IgG anti-T. gondii antibodies
in search of ocular toxoplasmosis.
Results: Fifty-four (34%) traffic accident drivers and 59 (36%) controls were positive to IgG anti-T. gondii antibodies
(p = 0.70). Among the 113 seropositive participants, mean anti-T. gondii IgG antibodies titers were higher in traffic
accident drivers than in controls (237.9 ± 308.5 IU/ml vs. 122.9 ± 112.7 IU/ml, respectively; p = 0.01 by Student’s t
test, p = 0.037 by Mann–Whitney U test). In multivariate analyses, anti-T. gondii IgG antibody titers were consistently
associated with an increased risk of traffic accidents, whereas age showed an inverse association. The presence of
IgM-anti-T. gondii antibodies was found in three (1.9%) subjects among traffic accident drives, and in two (1.2%)
controls. Three (4.2%) samples were positive for the presence of T. gondii DNA, all among seropositive individuals.
No signs of ocular toxoplasmosis were found in the entire cohort. Moreover, no other ocular conditions were found
to be associated with the risk of traffic accidents in a multivariate analysis.
Conclusions: Anti-T. gondii antibody titers are associated with the risk of traffic accidents. We could not determine
any association of ocular toxoplasmosis with traffic accidents. Our results warrant further analyses in order to clarify
the link between toxoplasmosis and traffic accidents.
People Living with Human Immunodeficiency Virus in Hadhramout: Clinical Prese...asclepiuspdfs
The objective of the study was to determine the clinical features and outcome of patients living with human immunodeficiency virus (HIV) in Hadhramout and nearby governorates. Materials and Methods: This descriptive study was conducted in the antiretroviral therapy (ART) site at Ibn-Sina General Hospital, Mukalla, Hadhramout governorate. All 145 patients were enrolled in HIV treatment and care program from December 2008 to the end of December 2016 with confirmed HIV test. Data included all personal data, clinical staging, drugs taken, and outcomes. Patients were grouped according to the decades to five groups, ≤15 years, 16–30 years, 31–50 years, 51–70 years, and >70 years. Cases classify according to the antiretroviral drugs to ART group and Pre-ART group. The relevant data parameters were analyzed using SPSS statistical software version 21 and Excel 10. Results: A total of 145 cases, most adults (97.9%), males and females were104 (71.7%) and 41 (28.3%), respectively. Mean age was 36.46 years and 30–50 years the most affected age group (55.2%). Clinical Stages 3 and 4 were the common presentation in 73.8%, and most cases were from Mukalla city. Of the total cases, 74.5% were on ART 53.1 of them improved, pulmonary tuberculosis was found in 4 cases, and death cases were (18.5%), mostly due to late presentation and non-adherence, and mostly occurred in early 6 months of starting the ART. 37 patients were in a pre-treatment group (21.6%), where the mortality rate is 35.1%, mainly due to loss of follow-up. Conclusions: Most cases were adult males, young age and have had late presentation, where mortality is higher in the pre-treatment group due to loss of follow-up and in early 6 months of treatment.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
Management of Fournier’s Gangrene in a Low Resource Settingasclepiuspdfs
external genitalia and perineum. Although the condition is rare in absolute terms, over 1726 cases have been reported in English literature, with a male/female ratio of 10:1. There have been 502 cases from Africa, which ranks second to the USA/Canada. At present, there is only one published literature on the management of FG in Liberia. Objective: This study highlig hts the late presentation and the challenges in the management of FG at the John F. Kennedy Medical Center. Methodology: This is a retrospective study of 30 patients with FG who were admitted and managed by our division of urology, from January 2018 to May 2019. The patient’s records were retrieved and reviewed for age, sex, onset of disease, sites of the disease, management, duration of stay, and outcome. The frequency and percentage of various parameters were displayed in tables.
Capstone thesis submitted for undergraduate studies on the utility of genomic surveying tools in improving sudden cardiac arrest risk stratification and prediction of sudden cardiac death.
Quality of life and its sociodemographic and clinicalpredictorsamong people o...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Evaluation of comorbid autoimmune diseases among patients and family members enrolled in the Alopecia
Areata Registry, Biobank & Clinical Trials Network.
frequency of hepatitis C virus infection in patients with type 2 diabetes mel...Dr Tarique Ahmed Maka
ABSTRACT
Objective: To determine the frequency of hepatitis C virus infection in patients with type 2 diabetes mellitus and to look for the common risk factors leading to this infection in diabetics. Study Design: Descriptive cross sectional study design. Place and Duration of Study: Department of Medicine, Combined Military Hospital (CMH) Kharian, from Jan 2015 to Jun 2015. Patients and Methods: This study was conducted in the department of Medicine, Combined Military Hospital Kharian. Through a descriptive cross sectional study design, a total of 140 patients with type 2 diabetes mellitus, admitted through casualty, OPD or private clinics were selected and tested for Hepatitis C virus infection. The common risk factors leading to such infection among positive cases were also scrutinized. Results: The mean age of patients was 48.82 ± 10.14 with 60.7% female gender predominating the overall sample of diabetics. Using 3rd generation ELISA method, hepatitis C virus was found in 45 (32.1%) of patients with 41-50 years of age group most commonly affected age group (34.7%) and female (57.8%) commonly affected gender. The distribution of risk factors leading to hepatitis C virus in diabetics are: 21 (46.7%) had history of surgery in the past, 13 (28.9%) had history of blood transfusion in the past, 7 (15.55%) had history of hemodialysis while only 4 (8.9%) had history of tattooing in the past. Conclusion: Hepatitis C virus infection is still a common problem in diabetic patients of our local population and we recommend further research work over its risk factors so that the guidelines for its control may be formulated. Keywords: Blood transfusion, Diabetes Mellitus, Haemodialysis, Hepatitis C virus infection, Risk Factors, Surgery, Tattooing.
Lady health workers' perceptions towards tuberculosis and its determinants at...Zubia Qureshi
Background: Lady Health Workers (LHWs), performing in Tuberculosis control programs have direct access in the communities. This study was designed to improve the TB status in Sindh province by improving the knowledge and practices of LHWs. Objective: To assess the TB related knowledge, attitude and practices among LHWs at tehsil Latifabad, district Hyderabad, Sindh. Method: A mixed method Cross-sectional study was done on universally selected 384 LHWs from Latifabad. Three focus group discussions were conducted with eight participants for each group. A pre-tested structured questionnaire and eld guidelines were used for data collection. Analysis was done on SPSS software by calculating frequencies, percentages, mean and median. While for inferential analysis chi square, t-test and Mann Whitney U tests were used. For FGDs, content analysis method was used. Results: Sufcient knowledge was found in about half 193(50.3%) of the participants. The overall attitude and practices of most of the LHWs 214(55.7%) and 205 (53.4%) respectively was not good. A signicant difference was found between LHWs knowledge score of those who had insufcient (28.08 ± 3.0) and sufcient knowledge (28.08 ± 3.1) with p-value <0.001. Also good attitude (47.74±2.8) and practices (51.45±3.8) of LHWs differed signicantly from those who did not have good attitude (36.09±4.8), and practices (40.44±3.3) with p-value <0.001. The insufcient knowledge was associated with unsafe practices. Tuberculosis related stigma was found in the community, people do not want to disclose their disease. Conclusion: Overall knowledge, attitude and practices about TB were not satisfactory among LHWs of Latifabad. An educational intervention is recommended for LHWs. Key words: Community health workers, infectious disease, knowledge, attitude, practices, developing country
1- Differentiate between primary and secondary sources and provide an.pdfcontact28
1. Differentiate between primary and secondary sources and provide an example for each one. 2.
Describe the similarities and differences between a research paper and a review paper. 4. Is the
following Abstract from a research article? Abstract People of African ancestry (Blacks) have an
increased risk of kidney failure due to numerous socioeconomic, environmental, and clinical
factors. Two variants in the APOL1 gene are now thought to account for much of the racial
disparity associated with hypertensive kidney failure in Blacks. However. this knowledge has not
been translated into clinical care to help improve patient outcomes and address disparities.
GUARDD is a randomized trial to evaluate the effects and challenges of incorporating genetic
risk information into primary care. Hypertensive, non-diabetic, adults with self-reported African
ancestry. without kidney dysfunction, are recruited from diverse clinical settings and randomized
to undergo APOL1 genetic testing at baseline (intervention) or at one year (waitlist control).
Providers are educated about genomics and APOL1. Guided by a genetic counselor, trained staff
return APOL1 results to patients and provide low-literacy educational materials. Real-time
clinical decision support ols alert clinicians of their patients' APOL1 results and associated risk
status at the point of care. Our academiccommunity-clinical partnership designed a study to
generate information about the impact of genetic risk information on patient care (blood pressure
and renal surveillance) and on patient and provider knowledge, attitudes, beliefs, and behaviors.
GUARDD will help establish the effective implementation of APOLL risk-informed
management of hypertensive patients at high risk of CKD, and will provide a robust framework
for future endeavors to implement genomic medicine in diverse clinical practices. It will also add
to the important dialog about factors contributing to and may help eliminate racial disparities in.
kidney disease. True: False 5. Of the 3 titles listed below, which title(s) is suitable for a review
paper: a. Chronic Kidney Disease Diagnosis and Management b. Determining the Effects and
Challenges of Incorporating Genetic Testing into Primary Care Management of Hypertensive
Patients with African Ancestry c. Pharmacist Intervention for Blood Pressure Control in Patients
with Diabetes and/or Chronic Kidney Disease d. all of the above 6. Which reference style is used
for citing electronic journal articles. a. DOI b. APA c. NLM d. MLA e. all of the above f. none of
the above.
People Living with Human Immunodeficiency Virus in Hadhramout: Clinical Prese...asclepiuspdfs
The objective of the study was to determine the clinical features and outcome of patients living with human immunodeficiency virus (HIV) in Hadhramout and nearby governorates. Materials and Methods: This descriptive study was conducted in the antiretroviral therapy (ART) site at Ibn-Sina General Hospital, Mukalla, Hadhramout governorate. All 145 patients were enrolled in HIV treatment and care program from December 2008 to the end of December 2016 with confirmed HIV test. Data included all personal data, clinical staging, drugs taken, and outcomes. Patients were grouped according to the decades to five groups, ≤15 years, 16–30 years, 31–50 years, 51–70 years, and >70 years. Cases classify according to the antiretroviral drugs to ART group and Pre-ART group. The relevant data parameters were analyzed using SPSS statistical software version 21 and Excel 10. Results: A total of 145 cases, most adults (97.9%), males and females were104 (71.7%) and 41 (28.3%), respectively. Mean age was 36.46 years and 30–50 years the most affected age group (55.2%). Clinical Stages 3 and 4 were the common presentation in 73.8%, and most cases were from Mukalla city. Of the total cases, 74.5% were on ART 53.1 of them improved, pulmonary tuberculosis was found in 4 cases, and death cases were (18.5%), mostly due to late presentation and non-adherence, and mostly occurred in early 6 months of starting the ART. 37 patients were in a pre-treatment group (21.6%), where the mortality rate is 35.1%, mainly due to loss of follow-up. Conclusions: Most cases were adult males, young age and have had late presentation, where mortality is higher in the pre-treatment group due to loss of follow-up and in early 6 months of treatment.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
Management of Fournier’s Gangrene in a Low Resource Settingasclepiuspdfs
external genitalia and perineum. Although the condition is rare in absolute terms, over 1726 cases have been reported in English literature, with a male/female ratio of 10:1. There have been 502 cases from Africa, which ranks second to the USA/Canada. At present, there is only one published literature on the management of FG in Liberia. Objective: This study highlig hts the late presentation and the challenges in the management of FG at the John F. Kennedy Medical Center. Methodology: This is a retrospective study of 30 patients with FG who were admitted and managed by our division of urology, from January 2018 to May 2019. The patient’s records were retrieved and reviewed for age, sex, onset of disease, sites of the disease, management, duration of stay, and outcome. The frequency and percentage of various parameters were displayed in tables.
Capstone thesis submitted for undergraduate studies on the utility of genomic surveying tools in improving sudden cardiac arrest risk stratification and prediction of sudden cardiac death.
Quality of life and its sociodemographic and clinicalpredictorsamong people o...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Evaluation of comorbid autoimmune diseases among patients and family members enrolled in the Alopecia
Areata Registry, Biobank & Clinical Trials Network.
frequency of hepatitis C virus infection in patients with type 2 diabetes mel...Dr Tarique Ahmed Maka
ABSTRACT
Objective: To determine the frequency of hepatitis C virus infection in patients with type 2 diabetes mellitus and to look for the common risk factors leading to this infection in diabetics. Study Design: Descriptive cross sectional study design. Place and Duration of Study: Department of Medicine, Combined Military Hospital (CMH) Kharian, from Jan 2015 to Jun 2015. Patients and Methods: This study was conducted in the department of Medicine, Combined Military Hospital Kharian. Through a descriptive cross sectional study design, a total of 140 patients with type 2 diabetes mellitus, admitted through casualty, OPD or private clinics were selected and tested for Hepatitis C virus infection. The common risk factors leading to such infection among positive cases were also scrutinized. Results: The mean age of patients was 48.82 ± 10.14 with 60.7% female gender predominating the overall sample of diabetics. Using 3rd generation ELISA method, hepatitis C virus was found in 45 (32.1%) of patients with 41-50 years of age group most commonly affected age group (34.7%) and female (57.8%) commonly affected gender. The distribution of risk factors leading to hepatitis C virus in diabetics are: 21 (46.7%) had history of surgery in the past, 13 (28.9%) had history of blood transfusion in the past, 7 (15.55%) had history of hemodialysis while only 4 (8.9%) had history of tattooing in the past. Conclusion: Hepatitis C virus infection is still a common problem in diabetic patients of our local population and we recommend further research work over its risk factors so that the guidelines for its control may be formulated. Keywords: Blood transfusion, Diabetes Mellitus, Haemodialysis, Hepatitis C virus infection, Risk Factors, Surgery, Tattooing.
Lady health workers' perceptions towards tuberculosis and its determinants at...Zubia Qureshi
Background: Lady Health Workers (LHWs), performing in Tuberculosis control programs have direct access in the communities. This study was designed to improve the TB status in Sindh province by improving the knowledge and practices of LHWs. Objective: To assess the TB related knowledge, attitude and practices among LHWs at tehsil Latifabad, district Hyderabad, Sindh. Method: A mixed method Cross-sectional study was done on universally selected 384 LHWs from Latifabad. Three focus group discussions were conducted with eight participants for each group. A pre-tested structured questionnaire and eld guidelines were used for data collection. Analysis was done on SPSS software by calculating frequencies, percentages, mean and median. While for inferential analysis chi square, t-test and Mann Whitney U tests were used. For FGDs, content analysis method was used. Results: Sufcient knowledge was found in about half 193(50.3%) of the participants. The overall attitude and practices of most of the LHWs 214(55.7%) and 205 (53.4%) respectively was not good. A signicant difference was found between LHWs knowledge score of those who had insufcient (28.08 ± 3.0) and sufcient knowledge (28.08 ± 3.1) with p-value <0.001. Also good attitude (47.74±2.8) and practices (51.45±3.8) of LHWs differed signicantly from those who did not have good attitude (36.09±4.8), and practices (40.44±3.3) with p-value <0.001. The insufcient knowledge was associated with unsafe practices. Tuberculosis related stigma was found in the community, people do not want to disclose their disease. Conclusion: Overall knowledge, attitude and practices about TB were not satisfactory among LHWs of Latifabad. An educational intervention is recommended for LHWs. Key words: Community health workers, infectious disease, knowledge, attitude, practices, developing country
1- Differentiate between primary and secondary sources and provide an.pdfcontact28
1. Differentiate between primary and secondary sources and provide an example for each one. 2.
Describe the similarities and differences between a research paper and a review paper. 4. Is the
following Abstract from a research article? Abstract People of African ancestry (Blacks) have an
increased risk of kidney failure due to numerous socioeconomic, environmental, and clinical
factors. Two variants in the APOL1 gene are now thought to account for much of the racial
disparity associated with hypertensive kidney failure in Blacks. However. this knowledge has not
been translated into clinical care to help improve patient outcomes and address disparities.
GUARDD is a randomized trial to evaluate the effects and challenges of incorporating genetic
risk information into primary care. Hypertensive, non-diabetic, adults with self-reported African
ancestry. without kidney dysfunction, are recruited from diverse clinical settings and randomized
to undergo APOL1 genetic testing at baseline (intervention) or at one year (waitlist control).
Providers are educated about genomics and APOL1. Guided by a genetic counselor, trained staff
return APOL1 results to patients and provide low-literacy educational materials. Real-time
clinical decision support ols alert clinicians of their patients' APOL1 results and associated risk
status at the point of care. Our academiccommunity-clinical partnership designed a study to
generate information about the impact of genetic risk information on patient care (blood pressure
and renal surveillance) and on patient and provider knowledge, attitudes, beliefs, and behaviors.
GUARDD will help establish the effective implementation of APOLL risk-informed
management of hypertensive patients at high risk of CKD, and will provide a robust framework
for future endeavors to implement genomic medicine in diverse clinical practices. It will also add
to the important dialog about factors contributing to and may help eliminate racial disparities in.
kidney disease. True: False 5. Of the 3 titles listed below, which title(s) is suitable for a review
paper: a. Chronic Kidney Disease Diagnosis and Management b. Determining the Effects and
Challenges of Incorporating Genetic Testing into Primary Care Management of Hypertensive
Patients with African Ancestry c. Pharmacist Intervention for Blood Pressure Control in Patients
with Diabetes and/or Chronic Kidney Disease d. all of the above 6. Which reference style is used
for citing electronic journal articles. a. DOI b. APA c. NLM d. MLA e. all of the above f. none of
the above.
Participation of the population in decisions about their health and in the pr...Pydesalud
Póster presentado por Lilisbeth Perestelo en el congreso Summer Institute for Informed Patient Choice (SIIPC14) celebrado del 25 al 27 de junio de 2014 en Dartmouth, Hanover (EEUU). Web: http://siipc.org
Contacto: lperperr@gobiernodecanarias.org
A study on awareness of diabetic complications among type 2 diabetes patientsiosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Role of the Biochemistry Labs in Promoting the Health Care Services for the I...IJERA Editor
The health care in the State of Kuwait depends to a greater extent on the biochemical and clinical labs attached
at each hospital. The data obtained from these laboratories will facilitate the process of diagnosing the disease
accurately. This will have a positive impact on the selection of appropriate treatment for the patients in general
and for diabetics specifically.
The main objective of this research was to build a profile for lab analysis and a database for building a
comprehensive system of integrated activities to raise health care for diabetic patients in Kuwait. The study
revealed the burden of admitted diabetic cases on the blood chemistry laboratory in Sabah Hospital (in relation
to length of stay and total numbers of lab requests). The aim was fulfilled by designing a model of the
biochemical tests for diabetics; filling in forms from the reality of patient data, completing and analyzing the
results electronically.
The study showed the importance of biochemical and clinical labs since they act as the link of patient's
information at the secondary health care level.
Health Seeking Behaviors following Diabetes Mellitus of Various Ethnic Groups...ijtsrd
The research on Health Seeking Behaviours following Diabetes Mellitus DM of various ethnic groups was conducted because different patients within a given ethnic group or cultural group have different options regarding actions to seek health care services. The purpose of this study was to determine the Health Seeking Behaviours HSB following DM patients from various ethnic groups and the roles of the Health Psychologists HP on the DM patients in Nkwen Health District of Bamenda III Subdivision within Mezam Division of the North West Region of Cameroon. A descriptive survey research design was conducted among 230 sampled DM patients from various ethnic groups in Nkwen Health District. A non probability purposive sampling technique was used to set the population under study. The data was collected using both Focus Groups Discussions FGDs and questionnaire for a period of two months during the period that the DM patients came to Nkwen Health District either to consult or to refill their drugs. The questionnaire were administered to 230 DM patients from the various ethnic groups which were Bali, Bafut, Banso, Bamendankwe, Babanki, Santa, Nkwen and Ndu during this period as well.. The data collected was analysed using both descriptive and inferential statistics with SPSS software tool version 20.0, following the objectives of the study. For HSB, 38.3 agreed that they sought health care from traditional medicine whereas 26.1 remained neutral on traditional medicine. On the other hand, 37.7 disagreed that they used traditional medicine. Cultural believes and distance deterred HSB which were statistically significant with P = 0.001 and P= 0.001 respectively. The options taken to seek health care from the hospital were influenced by family relatives with P=0.001. Therefore, HSB was found to be statistically significant for the first traditional medicine and second line hospital among the different ethnic groups with P = 0.001 and 0.001 respectively. These results showed that poor HSB following DM among the different ethnic groups was statistically significant in Nkwen Health District. Foncham Paul Babila "Health-Seeking Behaviors following Diabetes Mellitus of Various Ethnic Groups in Nkwen Health District of Bamenda III Subdivision, Mezam Division, North West Region of Cameroon" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5 , August 2022, URL: https://www.ijtsrd.com/papers/ijtsrd51783.pdf Paper URL: https://www.ijtsrd.com/humanities-and-the-arts/psychology/51783/healthseeking-behaviors-following-diabetes-mellitus-of-various-ethnic-groups-in-nkwen-health-district-of-bamenda-iii-subdivision-mezam-division-north-west-region-of-cameroon/foncham-paul-babila
Risk factors of chronic liver disease amongst patients receiving care in a Ga...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
A Survey and Analysis on Classification and Regression Data Mining Techniques...theijes
Classification and regression as data mining techniques for predicting the diseases outbreak has been permitted in the health institutions which have relative opportunities for conducting the treatment of diseases. But there is a need to develop a strong model for predicting disease outbreak in datasets based in various countries by filling the existing data mining technique gaps where the majority of models are relaying on single data mining techniques which their accuracies in prediction are not maximized for achieving expected results and also prediction are still few. This paper presents a survey and analysis for existing techniques on both classification and regression models techniques that have been applied for diseases outbreak prediction in datasets.
Adherence to Antiretroviral Therapy among HIVPositive Patients in Central Hos...Efe Clement Abel
Abstract: Adherence is the quantified level to which an individual follows a prescribed treatment and a low level of adherence to antiretroviral therapy(ART) adversely affects a patient’s treatment outcome and results in a rebound of plasma viraemia, development of resistant strains of HIV, more rapid immune deterioration, development of AIDS and death. This study is aimed at assessing the level of adherence to ART among HIV-positive patients assessing care in Central Hospital, Warri, Delta State, Nigeria. A descriptive cross-sectional study. Data were obtained using a semi-structured, interviewer-administered questionnaire and analysed using SPSS version 23. A total of 303 persons were recruited for the study. The mean age of respondents was 36.2±10.8years. Less than half of the subjects (45.5%) were adherent to their ART. Among the non-adherent subjects, the common reasons reported for missing doses of ART were forgetfulness (50.9%), too busy with other things (43.6%) and away from home (35.8%). This study showed that adherence to ART among the study population was poor. Forgetfulness, too busy with other things and being away from home were the most common reason for non-adherence. It is, therefore, recommended that; regular health education should be organised for HIV patients on ART on the importance of being adherent to their ART, regular assessment of adherence to ART should be carried out and a method of reminding patients who are non-adherent to ART on the need to take their ART as at when due should be considered as part of the routine services provided by ART centres.
Evaluation factors contributing to the treatment default by tuberculosis pati...PUBLISHERJOURNAL
Tuberculosis (TB) is one of the biggest public health problem and now ranks alongside Human Immunodeficiency Virus (HIV) as the world’s leading infectious cause of death. Globally, patient compliance with anti-TB therapy estimated as low as 40% in developing countries, remains the principle cause of treatment failure. The aim of this study was to establish the factors contributing to treatment default by Tuberculosis patients at ART clinic in Ishaka Adventist Hospital, Bushenyi District. A cross-sectional and descriptive study which employed both qualitative and quantitative approach of data collection were used. The study was conducted in ART clinic at Ishaka Adventist Hospital, Bushenyi District and it took a period of four weeks. A purposive sampling technique was used to select the study participants. Results showed that out of 38 study participants, majority 26 (68%) were of age 30 years and above. A large proportion 24 (63%) of the participants were unemployed compared to the least 14 (37%) who were employed. Majority 21 (55%) travel at a distance of 10km and above to get TB treatment. Out of 38 participants, majority 26 (68%) did not informed the family or friends when they were on TB treatment. Of 26 participants 16 (61.5%) had fear of being isolated and 2 (7.7%) were other reason of no support. A large proportion of participants rated the attitude of staff who attended to them at the health facility to be unfriendly with 21 (55%) while very few 6 (16%) were rude. The ministry should ensure availability of and access to resources for strengthening systems for delivery of quality tuberculosis treatment, prevention and control.
Keywords: treatment, default, tuberculosis, ART, Uganda
Evaluation factors contributing to the treatment default by tuberculosis pati...PUBLISHERJOURNAL
Tuberculosis (TB) is one of the biggest public health problem and now ranks alongside Human Immunodeficiency Virus (HIV) as the world’s leading infectious cause of death. Globally, patient compliance with anti-TB therapy estimated as low as 40% in developing countries, remains the principle cause of treatment failure. The aim of this study was to establish the factors contributing to treatment default by Tuberculosis patients at ART clinic in Ishaka Adventist Hospital, Bushenyi District. A cross-sectional and descriptive study which employed both qualitative and quantitative approach of data collection were used. The study was conducted in ART clinic at Ishaka Adventist Hospital, Bushenyi District and it took a period of four weeks. A purposive sampling technique was used to select the study participants. Results showed that out of 38 study participants, majority 26 (68%) were of age 30 years and above. A large proportion 24 (63%) of the participants were unemployed compared to the least 14 (37%) who were employed. Majority 21 (55%) travel at a distance of 10km and above to get TB treatment. Out of 38 participants, majority 26 (68%) did not informed the family or friends when they were on TB treatment. Of 26 participants 16 (61.5%) had fear of being isolated and 2 (7.7%) were other reason of no support. A large proportion of participants rated the attitude of staff who attended to them at the health facility to be unfriendly with 21 (55%) while very few 6 (16%) were rude. The ministry should ensure availability of and access to resources for strengthening systems for delivery of quality tuberculosis treatment, prevention and control.
Keywords: treatment, default, tuberculosis, ART, Uganda
ER(Entity Relationship) Diagram for online shopping - TAEHimani415946
https://bit.ly/3KACoyV
The ER diagram for the project is the foundation for the building of the database of the project. The properties, datatypes, and attributes are defined by the ER diagram.
This 7-second Brain Wave Ritual Attracts Money To You.!nirahealhty
Discover the power of a simple 7-second brain wave ritual that can attract wealth and abundance into your life. By tapping into specific brain frequencies, this technique helps you manifest financial success effortlessly. Ready to transform your financial future? Try this powerful ritual and start attracting money today!
Multi-cluster Kubernetes Networking- Patterns, Projects and GuidelinesSanjeev Rampal
Talk presented at Kubernetes Community Day, New York, May 2024.
Technical summary of Multi-Cluster Kubernetes Networking architectures with focus on 4 key topics.
1) Key patterns for Multi-cluster architectures
2) Architectural comparison of several OSS/ CNCF projects to address these patterns
3) Evolution trends for the APIs of these projects
4) Some design recommendations & guidelines for adopting/ deploying these solutions.
1.Wireless Communication System_Wireless communication is a broad term that i...JeyaPerumal1
Wireless communication involves the transmission of information over a distance without the help of wires, cables or any other forms of electrical conductors.
Wireless communication is a broad term that incorporates all procedures and forms of connecting and communicating between two or more devices using a wireless signal through wireless communication technologies and devices.
Features of Wireless Communication
The evolution of wireless technology has brought many advancements with its effective features.
The transmitted distance can be anywhere between a few meters (for example, a television's remote control) and thousands of kilometers (for example, radio communication).
Wireless communication can be used for cellular telephony, wireless access to the internet, wireless home networking, and so on.
1.Wireless Communication System_Wireless communication is a broad term that i...
150326 395078-1-sm
1. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
Indigenous Knowledge Systems for the treatment of
Hypertension in Lusaka, Zambia: Perceptions,
Knowledge and Practice
F Goma1
*, L Prashar C.A. Kalungia A BwalyaZ, A Hamachila
R.K. MutatiEZingani C Mwila P Musoke
2
1
Department ofPhysiological Sciences, University ofZambia School ofMedicine,
2
Department ofPharmacy, University ofZambia School ofMedicine
ABSTRACT
Background: A significant number of patients suffering
from hypertension, a major risk factor for cardiovascular
morbidity, are said to access traditional medicine (TM)
for their disease management. Traditional medicine,
originating from indigenous knowledge that has been
passed on from generation to generation, has remained
largely under-researched. There is paucity ofinformation
on the efficacy and toxicity ofthese remedies. Indigenous
knowledge systems (IKS) as utilised in healthcare
provision in primary care settings have remained largely
understudiedinZambia.
Objectives: The study aimed to determine the knowledge
of aetiology, risk factors, diagnosis, mode of treatment
and complications of hypertension among Traditional
HealthPractitioners (THP) in Lusaka.
Methods: A descriptive cross-sectional study was
conducted of THPs registered with the Traditional
Healers & PractitionersAssociation ofZambia (THPAZ)
operating from within Lusaka district who provided
treatment for hypertension using indigenous TM. A
structured interviewer-administered questionnaire was
utilised to gather quantitative and qualitative data. A total
oftwelve (12) THPs were interviewed.
*Corresponding Author:
Dr Fastone Goma,
University ofZambia School ofMedicine,
P.O. Box 50110, Lusaka, Zambia.
Email: gomafm@unza.zm, gomafm@yahoo.co.uk
156
Results: Majority (11/12) of THPs had limited basic
knowledge of some causes of hypertension although
three (3) of them mentioned bewitchment as one of the
causes. Divination was the preferred method ofdiagnosis
for 6 (50%) of them. Most of them described and
identified common risk factors and complications of
hypertension. In this study, all THPs (100%) used
indigenous traditional herbal remedies, usually mixtures
of various plants and/or different parts of plants to treat
hypertension. There were no unifiedmodes ofmonitoring
efficacy and safety of the medicaments administered to
patients.
Conclusion: This study reveals severe gaps in the
knowledge, perception and practice of THPs who still
rely largely on spiritual divination to make the diagnosis
of hypertension, with a few of them ascribing the
pathophysiology to witchcraft. Use of indigenous
traditional herbal remedies by THPs was widely
practiced. There is need to subject the available remedies
to more scientific evaluation to determine their possible
efficacyand safetyformanaginghypertension.
INTRODUCTION
Indigenous knowledge systems (IKS), refers to age-old
long-standing traditions and practices involving wisdom,
knowledge, teachings of communities and traditional
technologies, which have made a significant contribution
to modem medicine, having led to the discovery of
Key words; hypertension, traditional health practitioners,
indigenous knowledge, medicinalplants.
L.T. Muungo
2
2. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
hundreds of new drugs.1
Traditional Medicine (TM) as
practiced by traditional health practitioners (THPs) is the
sum total of knowledge or practices that enables
diagnosing, preventing or eliminating a physical, mental
or social disease which relies on IKS experiences.'·
2 3
A
traditional health practitioner (THP) is a community
member recognized as competent to provide health care
using traditional methods. Traditional healthpractitioners
include herbalists, bone setters, traditional psychiatrists,
traditional paediatricians, traditional birth attendants,
occult practitioners, herb sellers, and general
practitioners. Thus, TM encompasses therapeutic
practices that include the use ofherbalmedicines.
4
Inadequate healthcare systems in Africa and inability to
access anti-hypertensive drugs, has made traditional
herbal medicine popular among hypertensive patients
with reported prevalence of80% in Morocco and 28% in
South Africa.5
'
6
The exact prevalence use of indigenous
TM in Zambia remains to be established, though it is
likely to be similar to that reported in other sub-Saharan
countries.
Hypertension, a condition characterized by a blood
pressure measuring ~ 140/90 mmHg caused by various
genetic and/or environmental factors, is a major risk
factor for cardiovascular morbidities such as peripheral
vascular disease, stroke andrenal disease among others.7
'
8
'
9
The World Health Organization (WHO) estimated that
7.1 million people died prematurely as a result of
hypertension in 2008.7
Hypertension was reported as the
highest non-communicable disease cause ofdeath.6
With
a prediction that 1.56 billion adults will be hypertensive
by 2025, the current global prevalence stands at
approximately 800 million people indicating that
hypertension will continue to pose a heavy burden to
health care systems.7
'
9
Developing countries, including
Zambia, are undergoing an epidemiological transition
from communicable to non-communicable diseases
(NCDs) which have been reported to be responsible for
60% ofdeaths caused by cardiovascular diseases among
others.
10
About 40 to 50% ofthe adult African population
has hypertension most ofwhich remain undiagnosed.
6
In
Zambia, Goma et al reported a hypertension prevalence
157
of34.8% among adults inLusakaurban.
11
IKS used for traditional healing of disease have a very
strong cultural influence. Various surveyshave confirmed
thatboth high andlow income people at one pointresortto
herbal and alternative therapies.6
'
9
'
12
'
13
'
14
Sociocultural and
ethnic beliefs about disease explain why THPs are
commonly recognised as alternative health care providers
in most sub-Saharansocieties.15
•
19
ltis currentlynotknown
on what basis Zambian THPs manage hypertension. The
aim of this study was to determine the perceptions,
knowledge and practices ofiKS used in the management
ofhypertensionbyTHPs inLusaka, Zambia.
METHODOLOGY
A descriptive cross-sectional study was undertaken in
February to August 2015. The Traditional Healers &
Practitioners Association of Zambia (THPAZ) was
engaged to identify the registered THPs providing
treatment of hypertension within Lusaka District. A
functional alliance was built with THPAZ through the
signing of the Protection and Mutually Agreed Terms
document containing agreed terms for collecting general
and intellectual property-related information concerning
their remedies.21
A list of nineteen (19) THPs providing
IKS-based treatment for hypertension was obtained from
THPAZ out ofwhich twelve (12) participatedin the study.
Quantitative and qualitative data was collected using a
structured interviewer-administered questionnaire. Four
(4) research assistants (postgraduate students) trained in
interview techniques conducted the interviews at the
THPs work premises in various areas of Lusaka City.
Quantitative data was processed using Microsoft® Excel
2010 package whereas qualitative data was transcribed
and analyzed using the deductive content analysis
procedure.
22
The study protocol complied with guidelines on
Traditional Knowledge & Plant Genetic Resources by the
Southern Africa Network for Biosciences (SANBio).
23
Ethical approval to undertake the studywas grantedby the
Ethics Review Committee of the Tropical Diseases
Research Centre (TDRC) ofZambia. The purpose ofthe
study, its methods & procedures were explained to the
3. Medical Journal ofZambia, Vol. 43 (3): pp 156- 166 (2016)
participants andwritten consentwas dulyobtained. From
each THPinterviewed, an inventory ofindigenous herbal
preparations and the parts of the plants used for the
treatmentofhypertensionwas obtained. Datacollectedin
thesurveywastreatedwithmaximumconfidentialityand
nonamesofparticipants,theirdetailsofpracticeornames
ofpremises were disclosed. Permission to publish any of
thefindings ofthisstudywas soughtfrom all participants
andstakeholdersinvolved.
RESULTS
Figure 1: Geographic distribution of participants by
locationinLusakadistrict
(A)
''.
a
(B)
•
Lusaka
m
Ulayl
'',,
m
'·': l
,.. ' Cl
I LU$aka f
--·-.....
•• •
ID •
1111::11
/ "-..
" ..,•
'
•...
-
Geographical mapping ofsurvey sites; (A) Lusaka district, (B)
Participant THP clinic locations in Lusaka. (Maps courtesy of
GoogleMaps®,www.google.co.zmlmQPs)
158
Table 1: Participant Sodal Demograpbica
Variable Deacriptlon No. of
putidp
ants
(n -l:ZJ
Sex - Male 5
- Female 7
.Age - 41 - SO years old 2
- 51 - 60 years old 3
- 61 -70 years old 3
- >80 yean~ old 1
~st - Primary level 5
Ed=ational - Junior Second.azy 2
level attained level (Gxadc 8 to 9}
- Upper Second.azy 2
level (Gxadc 10 to 12)
- None 3
Yean~ of - More 1han 10 yean~ 12
practice as THP
Number of - Leas than one per 2
hypertensive week 1
patients - One to Two per week 5
attended to per - Two to Three per 4
week week
- More than three per
week
Among the THPs interviewed, 7 were female and 5 were
male with an age range of41 to 81 years. Majority(9/12)
indicated having attended formal education with 2 of
them having reached grade 12 whereas 3 had no formal
education at all. All the participants had more than 10
years'experienceasTHPs.
UnderstandingofhyperteJuion
THP11' No. of Selected dinlct quote. from
understaDding respODiel responses given byparticipants
of aligned to
hypertension. theme
DiseaBe 3 "diseasethat affecis the heartand
affcct:ingthe leads to overworldngofthe
heart heart..."-Rl
"diseasethat affects heart..."-
R3
"illness thataffects the heart,
bloodmovesfast.....-R2
Blood flowing 3 "fastnwvingofblood
fast acco11lpQIIiedwithfast breathmg
sweatingandpam..."-R4
"disturbanceofbloodflow, for
example, aftera bereavement...."
-RIO
"bloodis runningtoo much...."-
R7
4. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
Heart beating 3 "fast beating ofheart and comes
fast in different ways.... " - R5
"heartpalpitations... "- R12
"heart beatingfaster.... "- R8
Result ofstress 2 "illness that is as a result of
stress... " - R8 "alcohol, fatty
meat, mental stress... " - Rll
Body 3 "weakness andpain ofthe
weakness& heart.... " -R9
pain
"body weakness, fever, pain in
leg, stroke.... " -R12
"sweating and headache,
weakness ofbody... " - R2
R=RespondentNo.
THPs had very varied understanding of hypertension.
Descriptions of hypertension included: "disease that
affects the heart, blood flowing fast, body weakness,
breathing fast", or simply put as "the illness that results
from mental stress".
Table3: THPs PERCEPTIONSABOUT CAUSES OF
HYPERTENSION (HTN)
Perceived causes oC No. oC
Hypertension Responses
Stress of life 6
Diet 5
Spiritual forces 3
Social factors 10
Causes ofhypertension
Possible causes of hypertension described by THPs
included: unhealthy diets (consumption offatty meat and
alcohol, mental stress, social factors such as bereavement
and spiritual forces including witchcraft. Majority of
participants (11/12) acknowledged that high salt intake,
lack ofphysical activity (10/12), obesity (9/12), chronic
alcoholism (8/12) and chronic tobacco use (6/12) can
cause hypertension. Few (5/12) THPs acknowledged that
hypertension could be hereditary while 6/12 totally
disagreed. Majority of them (11/12) described
hypertension as a non-communicable disease with 10/12
believing that hypertension could be completely cured by
theirTMremedies.
159
Table 4: THPs PERCEPTIONS ABOUT
COMPLICATIONS OFHYPERTENSION (HTN)
Complications of Hypertension No. of
Responses
Stroke 7
Oedema 4
Heart Pain 4
Weakness & Collapse 3
Death 3
Heart enlargement 2
Others* 5
*Blindness, paralysis, infection (e.g. malaria), loss of speech,
andconstipation.
HTN=Hypertension
Understanding complications ofhypertension
All THPs acknowledged that untreated hypertension can
lead to complications. Stroke (7), pedal oedema (4),
precordial chestpain(4), weakness andcollapse (3), death
(3), heart enlargement (2), blindness, paralysis and loss of
speech were among complications mentioned. A few
unrelated conditions were also mentioned as
complications of hypertension such as malaria (1) and
constipation (1).
TABLE 5: BELIEFS ABOUT CAUSES OF
HYPERTENSION (HTN)
Beliefs on Hypertension
Increased salt in the diet
causesHTN
Obesity causes HTN
Chronic alcoholism causes
HTN
Lack ofphysical activity
causesHTN
Chronic tobacco use
causesHTN
HTN can be hereditary
Untreated hypertension
causes death
Untreated infectious
diseases cause HTN
HTN can be transmitted
HTN can be cured
Traditional medicines can
completely cure HTN
*NR = No response
HTN = Hypertension
Responses
A2ree Disa2ree Don't Know
11 0 1
9 2 NR
8 2 2
10 2 0
6 3 3
5 6 1
11 1 0
8 2 2
0 11 1
11 0 1
10 2 0
5. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
Table 6: THPs METHODS OF DIAGNOSIS & MANAGEMENT OF HYPERTENSION
THPs' method of diagnosis
of hypertension.
Spirits' revelation
Physical appearance of
patient
Diagnosis done at local
clinic
Patients' description of
complaints & symptoms
No. of
responses
aligned to
theme
6
2
2
3
Selected direct quotes from responses
given by participants (coded)
"••.through spiritual divination. Patients
explain their illness..... " - Rl
"spirits, demons communicate ifpatient
has BP... " - R2
"observingphysical weakness... "- R3
"Patientpresents with tremors ... "- R7
"Patient consult after BP h as been
diagnosed at the hospital... " - R8
"client comes with resultfrom hospital
revealing BP... " - R2
"From complaints, heartpumpingfast,
some collapse... " - R9
"clients will say the heart races... " - Rl0
"Patientpresents with tremors and heart
palpitations... " - R7
THPs' management of hypertensive patient after diagnosis
Giving traditional medicine 11
160
"give traditional medicationfor BP,
detoxifY the body... " - Rl0.
"give quarter teaspoon ofpowdered drug
in a glass ofwater... " - R7.
"tellpatient to putpowder in porridge,
soak root in water and waterput in
porridge, pound the leaves and
administer... "
"lemons to dissolvefat, other herbal
medicines... "
6. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
Counsel & advice patient 5
Spiritualgucidance 1
Observe & review 1
THPs' determination of treatment effectiveness
Diuresis effect
Patient feedback
Physical appearance of
patient improvement
2
4
3
Spirits confirm that patient is 3
cured
Confirmation at local
clinic/hospital
3
161
"advice on avoiding
temper/tension...advice on water
therapy... " - R2.
"counselpatient to relax and not
stressing over life...give them traditional
medicine" - R8.
"...tellpatients not to eatfast foods ... " -
R9.
"...spirits also communicate to explain
the process... " - Rl.
"give 1 or 2 weeks to check, review after
diagnosis and then give medication... " -
R12.
"patients indicate how theyfeel and
increase in micturition... " - R9
"patient starts passing urinefrequently.
They reportfeeling fine" - R7
"...patient confirms they arefeeling
better.... " -R4
"patients return to report that they are
fine" -RIO
"observe afterpatient has been to
hospitalfor medical check-up... " - R2
"see improvement in appearance of
patient... "
"....spirits confirm andpatient
corresponds... " - Rl
"through detection at the hospital.... " -
Rll
"refer to the hospitalfor BP checkup
where they report normal BP" - R7
7. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
Methods ofdiagnosing hypertension
Most common method of diagnosing hypertension
mentioned by TIIPs was use of spiritual mediums
(divination). Few THPs (3112) relied on patients'
description of symptoms, while 2/12 diagnosed from
physical appearance ofthe patient. Very few THPs (2/12)
relied on diagnosis done at the local health centre by
sphygmomanometry.
Treatment ofhypertension
While 11 out of 12 THPs would commence treatment on
first consultation, only 1 THP mentioned patient
counseling be done first and observe for 1 or 2 weeks
before commencing treatment. Majority ofthe IKS-based
remedies prescribed comprised herbal mixtures taken
orally. In addition to prescribing and dispensing remedies,
7/12 THPs accompanied this with advice (counseling) to
the patient. Advice comprised: "avoiding temper or
tension and advice on water therapy... "- R2, "patient to
relax andnotstressing over life..... "R8 and "...telling the
patients notto eatfastfood"- R6.
Table 7: TIIPs PERCEPTION OF THE EFFICACY
OFTHEIRMEDICATION
How long it takesfor your traditional medicine to start
working?
THPCount
Within 24 hours 6
24-72hours 1
More than 72 hours 4
Don't know 1
How long thepatient requires to take traditional medicine
for treatment ofhypertension to occur?
1 to 2 hours 3
12-24 hours 1
7 days 2
7-14 days 5
>3 months 1
THPs reported varied time to onset of action for the
various medicaments used. Six (6/12) THPs reported that
onset of action of their medication was within 24 hours
whereas 3 ofthem reported an onset time within 1-2 hours
while others reported thattheir medication startedto work
aftermore than 72 hours postdose.
162
Monitoring oftreatment
Participants acknowledged a process of monitoring
response to therapy. Two (2/12) THPs would observe for
increase urine output (diuresis), while some (3/12) THPs
relied on divine spiritual mediums to inform that
treatment had occurred. Three (3 out of 12) THPs used
physical appearance ofthe patients to evaluate treatment
response, whereas others (4/12) depended on patients'
feedback. Only 3 THPs relied on reviewing BP
measurements done at alocal governmenthealth facility.
DISCUSSION
This study is to our knowledge the first to detail the
utilisation of indigenous knowledge systems in the
management ofhypertension in Zambia. It reveals some
incorrect perspectives including definite gaps in the
knowledge and practice of hypertension management
among THPs in Lusaka. These require urgent mitigation
andhave serious implications for governmentpolicy.
Traditional healers' knowledge of hypertension and
its causes
There was clearly varied understanding of the disease
entity, its causes and complications. Majority ofTHPs in
this study mentioned mental stress, social problems and
spiritual forces including witchcraft as possible causes of
hypertension. While poor food choices (nutrition) were
mentioned among the causes of hypertension, there was
no direct relation to high sodium (salt) intake. These
findings demonstrate that traditional healers are aware
that hypertension may be caused by environmental
factors which are among the scientifically identified
causes of hypertension.
1
Similarly, Meli et al in
Cameroon found that 90% of traditional healers
perceived hypertension to be related to emotional stress
and genetic association.
24
In this study few THPs (42%)
mentioned any generic association. Witchcraft was
mentioned as cause ofhypertension by 3 ofthe 12 (25%)
respondents in this study. Comparatively, this was much
lower than that reported by Meli et al with 63% (19 of30
THPs) in Cameroon.
24
8. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
Methods ofdiagnosing hypertension
All the TIIPs acknowledged the importance ofmaking a
diagnosis before administering their medicaments.
Divination was the most common method of making a
diagnosis of hypertension, reported by 50% of TIIPs,
compared to mystical methods of diagnosis by 6.7% of
THPs in Cameroon.
24
This demonstrates that a majority of
THPs perceive the cause ofhypertension as being beyond
physiological causes thus requiring supernatural
interventionin its management.
Though a small number ofTHPs based their diagnosis on
patient's complaints and description of symptoms
(medical history only), this is considered inadequate for
patient evaluation in conventional medical practice
which requires that further physical examination,
physiological and biochemical measurements be done to
come up to an accurate diagnosis. While none of the
THPs in this study directly mentioned blood pressure
measurement as the basis of diagnosis, in Cameroon,
close to 24% ofthe traditional healers studiedknew about
the use of instruments that measure blood pressure.
Moreover, half of them owned and/or knew how to use
the sphygmomanometer for diagnosis while the others
relied onmedicalpersonnelfor diagnosis.
24
Knowledge ofcomplications ofhypertension
In this study, THPs' ranked stroke as the most highly
likely complication ofhypertension followed by oedema
and heart pain (table 4). The responses of the THPs do
indicate some level ofknowledge ofthe complications of
hypertension gained largely from experience with
patients inthe communities. Itis scientificallyproventhat
high blood pressure can result in stroke, kidney disease
with subsequent oedema and dementia. Ifhypertension is
untreated or not managed well, it can result into heart
failure presenting with chest pain, heart enlargement,
oedemaandultimately death.
25
Methods ofmanaging hypertension
The practice modalities of the THPs in this study were
overlapping between healing through divination and
herbalism. Majority of THPs alternated between these
modes by diagnosing through spiritual divination and
163
prescribing traditional herbal remedies from their vast
knowledge of indigenous systems. Traditional herbal
medicines were the treatment ofchoicebymajority (92%)
of the THPs. This was similar to Meli et al where 100%
traditional healers opted for TM in Cameroon.
24
In the
Zambian society, like many other sub-Saharan African
societies, THPs use indigenous knowledge to fulfil
different social and spiritual roles through mystical
divination, spiritual healing powers and concocting of
herbs and otheranimal products from natural sources. It is
through the mystic of spiritual divination practice that
THPs have long earned the respect and reverence from
among the communities they serve.
26
According to Van
Wyk et al, traditional healers, through dreams or during
prayers offered to spiritual mediums, believe they are
advisedwhich particularindigenous plants to collect for a
specific patient, including auspicious times for collecting
the plants and where these plants are located. The
traditional healer then supplements the perceived advice
from the 'spirits' with their own knowledge, training and
• 27
expenence.
Effectiveness and rating oftraditional methods
THPs cited various parameters they use to determine
effectiveness of the methods they use to treat
hypertension. Patient feedback was the most commonly
cited method followed by physical appearance,
confirmation at local clinic/hospital and spirits
confmning that patient is cured (in equal proportions)
whereas the presence of diuresis was the least cited.
Patient feedback and physical appearance are subjective
methods which may or may not be a reflection of the
progression of the underlying pathophysiological
processes of the condition. It is commonly recognized
among conventional/orthodox health practitioners that
many patients who suffer from hypertension may not
exhibit any physical symptoms to that effect. Increase in
urine output, though the least cited was an interesting
finding as a possible pointer to the probable mode of
action ofthe respective traditional herbal remedies used.
Several conventional drugs used in clinical management
ofhypertensionexerttheir actionby inducing diuresis and
the scientific rationale behind their use is well
9. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
documented and established.
28
The inference that the
respective remedies used were effective would be valid
only if blood pressure had been measured and patient
found to be hypertensive prior to treatment and
ascertained that the only intervention (TM remedy) had
induced the reduction in blood pressure (BP). This need
to be ascertained. Spiritualconfmnationthatthepatientis
cured isunscientific and difficultto validate.
Among the five emergent themes from THPs
determination of treatment effectiveness, evaluation of
BP measurements done at a local health facility or
hospital would be the most valid from a scientific stand
point as long as this would constitute BP
measurement/readings at diagnosis and following after
commencement of treatment for at least 24 hours.
Majority ofTHPs claimed that their TM onset of action
was within 24 hours (table 7). The validity ofthese claims
can onlybe confirmedusing scientific methods. AllTHPs
who participated in this study strongly claimed that their
IKS-based traditional medicines achieved complete cure
ofhypertension within three months. These claims were
in sharp contrast with current scientific understanding of
the pathophysiology and clinical management of
hypertension. It is commonly understood that
hypertension management is long-term.
29
Ifthe claims by
local THPs can be proved valid and reliable using
systematically validated evidence, a potential may exist
for a possibly radical contribution to the treatment of
hypertension. However, this seems to again expose the
THPs' lack of understanding of the pathophysiology of
hypertension. Potential exists to narrow this knowledge
gap.
Indicated localplantparts used for hypertension
All the respondents indicated using different plant parts
(table 8) in their crude forms either as single plant parts,
for instance roots only, or as mixtures to make decoction
and concoctions. Roots were the most mentioned,
followed by the leaves. The traditional herbal medicines
were mainly prepared as decoctions of powders taken
orally (e.g. added in porridge or taken as oral solutions).
All but two THPs in this study mentioned having more
than 2 types ofindigenous herbal preparations they used
164
for hypertension. Among the medicinal materials
mentioned by THPs for their preparations, three were not
of plant origin, these being crocodile fat, pebble and
honey, indicating that other natural products may be a
source of their medicines. It would be very important to
obtain the botanical names ofthe natural products that are
locally used and to elucidate their phytochemical
composition, pharmacological and toxicological
properties. Indigenous knowledge systems therefore
provide another avenue for promoting scientific research
on potential drug discovery of compounds for the
management ofhypertension. The urgent need to explore
thispotentialcannotbe overemphasized.
CONCLUSION
Indigenous knowledge systems as employed by local
THPs in the management of hypertension continue to
play a big role in bridging the health care provision gaps
existing in Zambia. This study reveals severe gaps in the
knowledge, perception and practice of THPs who still
rely largely on spiritual divination to make the diagnosis
of hypertension. Fundamental deviations and incorrect
perceptions, knowledge and practices need to be
addressed in order to narrow the knowledge gaps among
THPs who continue to offer health services to the
communities they serve. Use of indigenous traditional
herbal remedies by THPs was widely practiced. There is
need to subject the available remedies to more scientific
evaluation to determine their possible efficacy and safety
for managinghypertension.
ACKNOWLEDGEMENT
The authors acknowledge the tremendous collaboration
and support of THPAZ. This work was supported by a
research grant from National Science & Technology
Council (NSTC), through the Ministry of Science
&TechnologyofZambia.
DECLARATION OFINTEREST
The authors declare no conflict ofinterest associated with
this work and have no relevant affiliations or financial
involvement with any organization or entity with a
financial interest in or financial conflict with the subject
matter or materials discussed in this write-up. This
10. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
includes employers, consultancies, honoraria, patents
(received or pending), expert testimony, stock
ownership, orroyalties.
REFERENCES
1. Kaya, H.O., 2009,' Indigenous Knowledge (IK) and
innovation systems for public health in Africa', in F,
Kalua. , A, Awotedu., L, Kamwanja, L. & Saka, J
(eds), Science, technology and innovation for public
health inAfrica. Johannesburg, pp. 95-110, DS Print
Media.
2. Elujoba, A.A., Odeleye, O.M., Ogunyemi, C.M.
Traditional medicine development for medical and
dental primary health care delivery system in Africa.
Afr. J. Trad. CAM2005; 2: 46-61.
3. Gondwe, M., Kamadyaapa, D.R., Tufts, M.,
Chuturgoon, A.A., Musabayane, C.T.
Sclerocaryabirrea [(A. Rich) Hochst.]
[Anacardiacceae] stem-bark ethanolic extract (SBE)
modulates blood glucose, glomerular filtration rate
(GFR) and mean arterial blood pressure (MAP) of
STZ-induceddiabeticrats. Phytomedicine2008; 15:
699-709.
4. Stabler, S.N., Tejani, A.M., Huynh, F., Fowkes C.
Garlic for the prevention ofcardiovascular morbidity
and mortality in hypertensive patients. Cochrane
Database ofSystematic Reviews. 2012, Issue 8. Art.
No.: CD007653. DOl:
10.1002/14651858.CD007653.pub2.
5. Eddouks, M., Maghrani, M., Lemhadri, A., Ouahidi,
M.L., Jouad, H. Ethnopharmacological survey of
medicinal plants used for the treatment of diabetes
mellitus, hypertension and cardiac diseases in the
south-east region of Morocco. J Ethnopharmacol
2002; 82:97-103.
6. Hughes, G.D., Aboyade, O.M., Clark, B.L., Puoane,
T.R. The prevalence of traditional herbal medicine
use among hypertensives living in South African
communities. BMC Complementary and Alternative
Medicine. 2013; 13:38
7. Osamor, P.E., Owumi, B.E. Complementary and
alternative medicine in the management of
hypertension in an urban Nigerian community. BMC
ComplAlternative Med2010, 10:36.
165
8. World Health Organization/International Society of
Hypertension: 2003. World Health
Organization/International Society of hypertension
(ISH) statement on management of hypertension. J
Hypertens. 2003; 21:1983-92.
9. Zhang, H.W, Tong, J., Zhou, G., Jia, H., Jiang, J.Y.
Tianma Gouteng Yin Formula for treating primary
hypertension. Cochrane Database of Systematic
Reviews 2012, Issue 6. Art. No.: CD008166. DOl:
10.1002/14651858.CD008166.pub2.
10.Zambian National Health demographics survey
Zambia-2008:
11. Goma, F.M, Nzala, S.H., Babaniyi, 0., et al.
Prevalence of hypertension and its correlates in
Lusaka urban district of Zambia: a population based
survey. InternationalArchives ofMedicine 2011,4:34
doi: 10.1186/1755-7682-4-34.
12. Mansoor GA. Herbs and Alternative therapies in the
hypertensiveclinic.A.llf.2001; 14:971-75.
13.Africa Health Workforce Observatory. Human
Resources for Health Country Profile Zambia.
Lusaka: 2010.
14. Lotika, A., Mabuza, L., Okonta, H. Reasons given by
hypertensive patients for concurrently using
traditional and western medicine at Natalspruit
Hospital in the Gauteng Province, South Africa.
African Journal ofPrimary Health Care & Family
Medicine, 2013. Available at:
<http://www.phcfm.org/index.php/phcfm/article/vie
w/458/639>. Date accessed: 30 Sep. 2015.
15. Jian, S., Agrawal, S. Perception of illness and health
care among Bhils: a study of Udaipur district in
southernRajasthan. Stud Tribes Tribals 2005; 3: 15-9.
16.Pinkoane,M.G.,Greeff,M.,William,M.J. The patient
relationship and therapeutic techniques of South
Sotho traditionalhealer. Curations. 2005; 8: 20-30.
17. Tabi, M.M, Powell, M., Hodnicki, D. Use of
traditional healers and modem medicine in Ghana. Int
Nurs Rev2006; 53: 52-8.
18. Barker, R.D., Millard, F.J., Malatsi, J, et al. Agarawal
SDE Valiere S. Traditional healers, treatment delay,
performance status and death form TB in rural South
Africa.IntJTubercLungDis 2006; 10:670-
11. Medical Journal ofZambia, Vol. 43 (3): pp 156 - 166 (2016)
19.Nelms, L.W, Gorski, J. The role of the African
traditional healer in women's health. J Transcult Nurs
2006; 17:184-9.
20. Report 13 ofthe Council on ScientificAffairs (A-97).
[cited 2007 February 14] Available from:
http://www.ama-assn.org/ama/pub/category/13644.
html.
21.Andrews, P.R, Borris, R., Dagne, E., et al. General
features of contracts for natural produts
collaborations (Technical Report). Pure and Appl.
Chern, 1996; 68:2325-32.
22. Krippendorff, K. Content analysis: an introduction to
its methodology 2004. Thousands Oaks, CA: Sage.
ISBN: 978-0-7619-1545-4.
23. SouthernAfrica Network for Biosciences (SANBio) I
NEPAD Planning and Coordinating Agency 2012.
Traditional knowledge and plant genetic resources
guidelines. Mumba, L.E., Marundu, W. (eds). ISBN:
978-0-621-41108-9.
24. Meli, J, Nkhe- Chungag, B.N., Tatou, J.G.D, Mope,
J.S., Kingue, S. Perceptions of the aetiology and
166
treatment of Hypertension among some Traditional
Healers in Cameroon. The Open Public Health
Journal, 2009, 2, 39-43 Available from: Accessed 29
Sep,2015.
25.Devereux, R.B., Alderman, M.H. Role ofpreclinical
cardiovascular disease in the evolution from risk
factor exposure to development of morbid events.
Circ.ahajournal.orglcontent. Accessed on 13 OCT,
2015.
26. Campbell, S.S, 1998,' Called to Heal'. Halfway
House: Zebra Press. ISBN1-86872-240-6.
27. Van fJYk, B.E, Oudtshoorn, B. V., Nigel, G., 2012,'
Medicinal Plants of South Africa. Pretoria.' Briza
Publications.ISBN978-1-875093-37-3.
28. Fukuda, M., Kimura, G. Pathophysiology of
antihypertensive therapy with diuretics. Hypertens
Res, 2006; 29:645-53.
29.Flack, J.M, Novikov, S. V., Ferrario, C.M Benefits of
adherence to anti-hypertensive drug therapy. Eur
HeartJ, 1996; SupplA: 16-20.