This document describes a study that compares ultrasound measurements of intima-media thickness (IMT) in the left and right common carotid arteries. The study analyzed ultrasound images of 1104 subjects and found that (1) there was no significant difference between IMT measurements on the left and right sides for healthy subjects, (2) IMT measurements were significantly higher for subjects with cardiovascular disease on both sides, and (3) IMT increased with age for both healthy and diseased groups. An automated system was developed and achieved comparable IMT measurements to manual delineation. The system achieved 64% accuracy in distinguishing healthy from diseased subjects using IMT from both carotid arteries.

1. Logic Mind Technologies
Vijayangar (Near Maruthi Medicals), Bangalore-40
Ph: 8123668124 // 8123668066
Title: A Comparison of ultrasound Intima-
media Thickness Measurements of the Left
and Right Common Carotid Artery
Abstract— The intima–media thickness (IMT) of the common carotid artery (CCA) is an
established indicator of cardiovascular disease (CVD). There have been reports about the
difference between the left and the right sides of the CCA IMT and their relation with
cardiovascular disease. In this study, we propose an automated system based on image
normalisation, speckle reduction filtering and snakes segmentation, for segmenting the
CCA, perform IMT measurements and provide the differences between the left and right
sides. The study was performed on 1104 longitudinal-section ultrasound images acquired
from 568 men and 536 women out of which 125 had cardiovascular symptoms (CVD). A
cardiovascular expert manually delineated the IMT for the normal and the CVD groups.
The corresponding (normal vs CVD) IMT mean ± standard deviation values for the left
and right sides were 0.74±0.24 vs 0.87±0.24 mm and 0.70±0.17 vs 0.80±0.18 mm
respectively. The main findings of this study can be summarised as follows: (1) there was
no significant difference between the CCA left side IMT and the right side IMT. These
findings suggest that the measurement of the CCA IMT on one side only is needed for the
normal group (and this is in agreement with other studies); (2) there were statistical
significant differences for the IMT measurements between the normal group and the CVD
group for both the left and the right sides; (3) there was an increasing linear relationship of
the left and right IMT measurements with age for the normal group; and to a lesser extend
for the CVD group; (4) no statistical significant differences were found between the manual
and the automated IMT measurements for both sides; (5) the best result for classification
disease modelling, using support vector machines (SVM), to discriminate between the
normal and the CVD groups was a 64±3.5% correct classifications score when using both
the left and the right IMT automated measurements. Further research is required for
estimating differences and similarities between left and right intima media complex
structure and morphology and their variability with texture features for differentiating
between the normal and the cardiovascular disease group.

2. Software & Hardware requirement:
1. Hardware requirement:
1. PC
2. RAM minimum 2GB
3. HDD minimum 100GB
2. Software requirement:
1. MATLAB 7.0
2. Signal processing toolbox
3. Image processing toolbox
4. Mathematical toolbox
PROJECT FLOW:
First Review:
Literature Survey
Paper Explanation
Design of Project
Project Enhancement explanation
Second Review:
Implementing 40% of Base Paper
Third Review
Implementing Remaining 60% of Base Paper with Future Enhancement
(Modification)
For More Details please contact
Logic Mind Technologies
Vijayangar (Near Maruthi Medicals), Bangalore-40
Ph: 8123668124 // 8123668066

3. Mail: logicmindtech@gmail.com