21. CO2 removal is inversely proportional to Minute Ventilation CO2 removal is inversely proportional to Effective Alveolar Ventilation Effective Alveolar Ventilation = Minute Ventilation – Dead Space Ventilation
22. COPD on ventilator on VC Vt 500ml, Fio2 40%, PEEP 4cms H2o RR10/mt, I:E 1:2 Po2 is 60, PCo2 is 68 Increase Vt to 500ml Increase RR 15 After one hr repeat ABG shows PO2 of 58 PCO2 of 83 Minute ventilation of 500x10=5000 Minute ventilation of 500x15=7500
27. Manipulate - I:E Ratio Pressure T ime Gives more time for expiration and reduces DH T insp . . I : E = 1 : 2 I : E = 1: 3 PEEP PIP PIP PEEP T insp . T exp Total cycle time
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29. RISE TIME 40 P CIRC cmH 2 O INSP EXP 30 20 10 0 10 -20 80 60 40 20 0 20 -80 40 60 0 4 8 12s 2 6 10 Slow rise Moderate rise Fast rise TE TE TE TI L min V .
49. Paw (cm H 2 O) Normal P Plat (Normal Compliance) Increased PIP } Increased P TA (increased Airway Resistance ) Increased Airway Resistance Begin Inspiration Begin Expiration P aw (cm H 2 O) Time (sec) Airway Resistance Distending (Alveolar) Pressure Expiration PIP Normal Inflation Hold (seconds)
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53. CYCLING AT 40% OF FLOW CYCLING AT 25% 0F PEAK FLOW PRESSURE SUPPORT Flow cycling Flow Time Peak flow 40% 25%