1.) a.What was the original definition of a virus before it could be seen with electron microscopy? Why is that definition no longer functionally useful? What is the current definition of a virus? b.What are the differences between cellular organisms (i.e., eukaryotes & prokaryotes) and viruses? Can antibiotics be used to treat viral infections? Interferons? Why or why not? Why are some more recently discovered viruses challenging some of these paradigms, especially the one that classifies viruses as non-living? Explain. Solution Ques-1: 1.) What was the original definition of a virus before it could be seen with electron microscopy? Why is that definition no longer functionally useful? What is the current definition of a virus? Answer: According to degeneracy hypothesis, viruses were considered as small cells that can live as parasites in other cells. The other definition of viruses before they were seen under electron microscopy is that the viruses are evolved from macromolecules such as protein and nucleic acid at the time of cells initially appeared on Earth. at the same time as cells first appeared on earth. These definitions are not worked because these viruses are not complete cells because they do not have conspicuous nucleus or cell membrane or any morphological cellular features when observed under electron microscope. Therefore, the new definition of virus has proposed that these are technically living species and it is a small in size composed of virion and a segment of nucleic acid covered by a protein coat referred as capsid often infectious in host cell.