The main components of protein family members of RISC complex are: Highly abundant and expressive genes get more easily available for silencing process. siRNA activities are all dependent on the expression level of the RNA strands. Pri-Mi RNA are transported out of the nucleus by exportin protein. Dicer converts it into double stranded micro RNA form. The micro RNA produced is complementary to the target mRNA. It can bind with the complementary strand of target mRNA and breaks it down. Solution The main components of protein family members of RISC complex are: Highly abundant and expressive genes get more easily available for silencing process. siRNA activities are all dependent on the expression level of the RNA strands. Pri-Mi RNA are transported out of the nucleus by exportin protein. Dicer converts it into double stranded micro RNA form. The micro RNA produced is complementary to the target mRNA. It can bind with the complementary strand of target mRNA and breaks it down..