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Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Deep Transfer Learning for Magnetic Resonance
Image Multi-class Classification
Yusuf Brima
brima.yusuf@aims.ac.rw
Supervised by
Professor Ernest Fokoué
epfeqa@rit.edu
February 9, 2021
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Outline
1 Citation
2 Problem
3 Literature Survey
4 Research Goal
5 Proposed Methodology
6 Dataset
7 Experimental Results
8 Conclusion
9 References
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Citation
Brima Y., Tushar M.,Kabir U, and Islam T, “Deep Transfer Learning for
Multi-class Brain MRI Classification”, November 2020, in submission to
IEEE/ACM-TCBB
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Problem
I Radiologists analyse brain MRI scans
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Problem
I Radiologists analyse brain MRI scans
I Painstakingly difficult and time-consuming
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Problem
I Radiologists analyse brain MRI scans
I Painstakingly difficult and time-consuming
I Lack of expertise in low-resource societies
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
State-of-the-art
I Chaplot et al 2006 [1], Classification of magnetic resonance brain
images using wavelets as input to Support Vector Machine and
Neural Network
I Limitation: Manual feature engineering
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
State-of-the-art
I Talo et al 2019 [2], Application of Deep Transfer Learning for
automated brain abnormality classification using MR images
I Limitation: Binary Classifier
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Research Goal
I Deep Transfer Learning
I Using
• National Institute of Neuroscience and Hospital (NINS)
• The Harvard Whole Brain Atlas
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
Formal Definition
D := {X , P(X)}
X = {x1, x2, x3, . . . , xn}, ∀xi ∈ X
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
Formal Definition
For domain D, a task is defined as:
T := {Y , P(Y |X)}
Y = {y1, y2, y3, . . . , yn}, ∀yi ∈ Y
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
Formal Definition
Therefore
DS := {XS , P(XS )}
XS = {xS1
, xS2
, xS3
, . . . , xSn
}, ∀xSi
∈ XS
YS = {yS1
, yS2
, yS3
, . . . , ySn
}, ∀ySi
∈ YS
DT := {XT , P(XT )}
XT = {xT1
, xT2
, xT3
, . . . , xTn
}, ∀xTi
∈ XT
YT = {yT1
, yT2
, yT3
, . . . , yTn
}, ∀yTi
∈ YT
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
The goal of Transfer Learning
Given
η : X ,→ Y where η ∈ H
∼
X = argmin
η∈H
{L (η(XSi
) 6= YSi
)}
And
RDT
:= P(η(XT ) 6= yT |
∼
X)
η∗
= argmin
η∈H
{RDT
(η(XT ), YT ,
∼
X)}
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
Figure 1: High-level formal representation of Transfer Learning
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
Figure 2: Proposed System Architecture
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Transfer Learning
Figure 3: Deep Transfer Learning Stages
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Dataset
Category Total Patients Total Slices
Normal 2 65
Degenerative Disease 8 223
Neoplastic Disease 8 277
Inflammatory Infectious Disease 5 189
Cerebrovascular Disease 15 376
Table 1: Harvard Whole Brain Atlas dataset contains 1133 T2-weighted
contrast-enhanced images
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Dataset
Figure 4: Sample Harvard Whole Brain MRI Dataset
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Experimental Results
Figure 5: Illustration of top miss-classified images after stage III of fine-tuning
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Experimental Results
Figure 6: Error Rates across the four model architectures
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Experimental Results
Figure 7: Accuracy across four different model architectures
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Experimental Results
Figure 8: Stage III confusion matrix
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
Conclusion
Figure 9: Proposed system deployment diagram
References
[1] S. Chaplot, L. Patnaik, and N. Jagannathan, “Classification of
magnetic resonance brain images using wavelets as input to support
vector machine and neural network,” Biomedical signal processing
and control, vol. 1, no. 1, pp. 86–92, 2006.
[2] M. Talo, U. B. Baloglu, and U. R. Acharya, “Application of deep
transfer learning for automated brain abnormality classification using
mr images,” Cognitive Systems Research, vol. 54, pp. 176–188,
2019.
Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References
End
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AIMS Block Presentation]{Deep Transfer Learning for Magnetic Resonance Image Multi-class Classification

  • 1. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Deep Transfer Learning for Magnetic Resonance Image Multi-class Classification Yusuf Brima brima.yusuf@aims.ac.rw Supervised by Professor Ernest Fokoué epfeqa@rit.edu February 9, 2021
  • 2. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Outline 1 Citation 2 Problem 3 Literature Survey 4 Research Goal 5 Proposed Methodology 6 Dataset 7 Experimental Results 8 Conclusion 9 References
  • 3. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Citation Brima Y., Tushar M.,Kabir U, and Islam T, “Deep Transfer Learning for Multi-class Brain MRI Classification”, November 2020, in submission to IEEE/ACM-TCBB
  • 4. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Problem I Radiologists analyse brain MRI scans
  • 5. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Problem I Radiologists analyse brain MRI scans I Painstakingly difficult and time-consuming
  • 6. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Problem I Radiologists analyse brain MRI scans I Painstakingly difficult and time-consuming I Lack of expertise in low-resource societies
  • 7. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References State-of-the-art I Chaplot et al 2006 [1], Classification of magnetic resonance brain images using wavelets as input to Support Vector Machine and Neural Network I Limitation: Manual feature engineering
  • 8. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References State-of-the-art I Talo et al 2019 [2], Application of Deep Transfer Learning for automated brain abnormality classification using MR images I Limitation: Binary Classifier
  • 9. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Research Goal I Deep Transfer Learning I Using • National Institute of Neuroscience and Hospital (NINS) • The Harvard Whole Brain Atlas
  • 10. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning Formal Definition D := {X , P(X)} X = {x1, x2, x3, . . . , xn}, ∀xi ∈ X
  • 11. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning Formal Definition For domain D, a task is defined as: T := {Y , P(Y |X)} Y = {y1, y2, y3, . . . , yn}, ∀yi ∈ Y
  • 12. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning Formal Definition Therefore DS := {XS , P(XS )} XS = {xS1 , xS2 , xS3 , . . . , xSn }, ∀xSi ∈ XS YS = {yS1 , yS2 , yS3 , . . . , ySn }, ∀ySi ∈ YS DT := {XT , P(XT )} XT = {xT1 , xT2 , xT3 , . . . , xTn }, ∀xTi ∈ XT YT = {yT1 , yT2 , yT3 , . . . , yTn }, ∀yTi ∈ YT
  • 13. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning The goal of Transfer Learning Given η : X ,→ Y where η ∈ H ∼ X = argmin η∈H {L (η(XSi ) 6= YSi )} And RDT := P(η(XT ) 6= yT | ∼ X) η∗ = argmin η∈H {RDT (η(XT ), YT , ∼ X)}
  • 14. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning Figure 1: High-level formal representation of Transfer Learning
  • 15. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning Figure 2: Proposed System Architecture
  • 16. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Transfer Learning Figure 3: Deep Transfer Learning Stages
  • 17. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Dataset Category Total Patients Total Slices Normal 2 65 Degenerative Disease 8 223 Neoplastic Disease 8 277 Inflammatory Infectious Disease 5 189 Cerebrovascular Disease 15 376 Table 1: Harvard Whole Brain Atlas dataset contains 1133 T2-weighted contrast-enhanced images
  • 18. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Dataset Figure 4: Sample Harvard Whole Brain MRI Dataset
  • 19. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Experimental Results Figure 5: Illustration of top miss-classified images after stage III of fine-tuning
  • 20. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Experimental Results Figure 6: Error Rates across the four model architectures
  • 21. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Experimental Results Figure 7: Accuracy across four different model architectures
  • 22. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Experimental Results Figure 8: Stage III confusion matrix
  • 23. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References Conclusion Figure 9: Proposed system deployment diagram
  • 24. References [1] S. Chaplot, L. Patnaik, and N. Jagannathan, “Classification of magnetic resonance brain images using wavelets as input to support vector machine and neural network,” Biomedical signal processing and control, vol. 1, no. 1, pp. 86–92, 2006. [2] M. Talo, U. B. Baloglu, and U. R. Acharya, “Application of deep transfer learning for automated brain abnormality classification using mr images,” Cognitive Systems Research, vol. 54, pp. 176–188, 2019.
  • 25. Citation Problem Literature Survey Research Goal Proposed Methodology Dataset Experimental Results Conclusion References End Thank You!