Sandeep Mewada Pharmacology & Medicinal Chemistry

1. Oxytetracycline
• Oxytetracycline was the second of the broad-
spectrum tetracycline group of antibiotics to
be discovered.
• Oxytetracycline works by interfering with the
ability of bacteria to produce essential
proteins.
• Without these proteins, the bacteria cannot
grow, multiply and increase in numbers.
• Oxytetracycline therefore stops the spread of
the infection and the remaining bacteria are
killed by the immune system or eventually
die.

2. Oxytetracycline

3. • Oxytetracycline is still used to treat
infections caused by Chlamydia
(e.g. the chest infection psittacosis,
• the eye infection trachoma,
• and the genital infection urethritis)
and
• infections caused by Mycoplasma
organisms (e.g. pneumonia).

4. Medical uses
• Oxytetracycline used to treat
spirochaetal infections, clostridial
wound infection and anthrax in
patients sensitive to penicillin.
• Oxytetracycline is used to treat
infections of the respiratory and
urinary tracts, skin, ear, eye and
gonorrhoea.

5. Side effects
•gastrointestinal and
• photosensitive allergic
reactions
•damage calcium-rich
organs, such as teeth and
bones.

6. Veterinary indications
• Oxytetracycline can also be
used to correct breathing
disorders in livestock.
• Oxytetracycline in animal feed
on the environment, bacteria,
and antimicrobial resistance.