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Prepared by: MARKTY T. BAYAWA
The Biology
of
CANCER
• is a disease caused by the failure to control cell
division.
• cells divide too often and eventually interfere
with normal body functions.
• mutations in the genes that regulate cell division.
CANCER
• When damage occurs to DNA, the replication and
transcriptional machinery may no longer be able to
read the DNA’s genetic information.
• These are the partial list of mutagens that are
found in our environment.
• Radiation X rays and gamma rays, Ultraviolet light, UV-A,
from tanning lamps UV-B, the cause of sunburn
• Chemicals Arsenic (Elemental form)
• Benzene, Dioxin, Polyvinyl chloride (PVC)
• Chemicals found in smoked meats and fish
• Asbestos, Alcohol, Cigarette tar, Food containing nitrates
(e.g., bacon, ham, hotdog)
Mutagenic and Carcinogenic Agents
VIRUSES CANCER
Hepatitis B virus (HBV) = LIVER CANCER
VIRUSES CANCER
Herpes simplex virus (HSV)
TYPE II UTERINE CANCER
VIRUSES CANCER
Epstein-Barr Virus = BURKITT’S LYMPHOMA
VIRUSES CANCER
Human T-cell lymphotropic virus (HTLV-1) =
LYMPHOMAS AND LEUKEMIA
VIRUSES CANCER
Papillomavirus = SEVERAL CANCERS
VIRUSES CANCER
INHERITED CANCER
• Leukemia
• Colorectal Cancer
• Breast cancer
• Lung Cancer
• Stomach Cancer
• Prostate cancer
• Certain Skin Cancers
• Retinoblastomas
• Endometrial cancer
INHERITED CANCER
TUMORS
• Tumor is a mass of cells not normally
found in a certain portion of the body
 BENIGN TUMOR is a cell mass that
does not fragment and spread beyond
its original area of growth.
 MALIGNANT TUMORS are harmful
because they may spread or invade
other parts of the body.
TUMOR
CLASSIFICATION
• Carcinoma - Cancers derived from epithelial cells.
(This group includes many of the most common cancers,
particularly in the aged, and include nearly all those
developing in the breast, prostate, lung, pancreas, and
colon.)
• Sarcoma - Cancers arising from connective tissue
(i.e. bone, cartilage, fat, nerve)
• Lymphoma and Leukemia - These two classes of
cancer arise from hematopoietic (blood-forming)
cells that leave the marrow and tend to mature in
the lymph nodes and blood, respectively.
CLASSIFICATION
• Germ Cell Tumor - Cancers derived from
pluripotent cells, most often presenting in the
testicle or the ovary (seminoma and
dysgerminoma, respectively).
• Blastoma - Cancers derived from immature
"precursor" cells or embryonic tissue. Blastomas
are more common in children than in older
adults.
CLASSIFICATION
• SURGICAL REMOVAL OF CANCER
• CHEMOTHERAPHY & RADIATION
• WHOLE BODY RADIATION
• NANOPARTICLE THERAPY
TREATMENT
Every satisfactory work is build by means of substantial references. I hereby
state to have legitimately exploited following sources in the making of my
project-
- Guaytton and Sutton’s Textbook of Medicinal Oncology Millenium Edition, ©
Froth Silk Publishers, Boston
- Comprehensive Practical Biology | Class XII
A biology practical plus projects textbook by Laxmi Publications Pvt. Ltd.
- Wikipedia.com
The Online Encyclopedia
- ICBSE Online Help Forum
http://www.projects.icbse.com/main.aspx
- TCYonline.com
A world class educational and tutorial site on the web
- Meritnation.com
REFERENCES
The Biology of Cancer

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The Biology of Cancer

  • 1. Prepared by: MARKTY T. BAYAWA The Biology of CANCER
  • 2. • is a disease caused by the failure to control cell division. • cells divide too often and eventually interfere with normal body functions. • mutations in the genes that regulate cell division. CANCER
  • 3. • When damage occurs to DNA, the replication and transcriptional machinery may no longer be able to read the DNA’s genetic information. • These are the partial list of mutagens that are found in our environment. • Radiation X rays and gamma rays, Ultraviolet light, UV-A, from tanning lamps UV-B, the cause of sunburn • Chemicals Arsenic (Elemental form) • Benzene, Dioxin, Polyvinyl chloride (PVC) • Chemicals found in smoked meats and fish • Asbestos, Alcohol, Cigarette tar, Food containing nitrates (e.g., bacon, ham, hotdog) Mutagenic and Carcinogenic Agents
  • 5. Hepatitis B virus (HBV) = LIVER CANCER VIRUSES CANCER
  • 6. Herpes simplex virus (HSV) TYPE II UTERINE CANCER VIRUSES CANCER
  • 7. Epstein-Barr Virus = BURKITT’S LYMPHOMA VIRUSES CANCER
  • 8. Human T-cell lymphotropic virus (HTLV-1) = LYMPHOMAS AND LEUKEMIA VIRUSES CANCER
  • 9. Papillomavirus = SEVERAL CANCERS VIRUSES CANCER
  • 11. • Leukemia • Colorectal Cancer • Breast cancer • Lung Cancer • Stomach Cancer • Prostate cancer • Certain Skin Cancers • Retinoblastomas • Endometrial cancer INHERITED CANCER
  • 13. • Tumor is a mass of cells not normally found in a certain portion of the body  BENIGN TUMOR is a cell mass that does not fragment and spread beyond its original area of growth.  MALIGNANT TUMORS are harmful because they may spread or invade other parts of the body. TUMOR
  • 14.
  • 15.
  • 17. • Carcinoma - Cancers derived from epithelial cells. (This group includes many of the most common cancers, particularly in the aged, and include nearly all those developing in the breast, prostate, lung, pancreas, and colon.) • Sarcoma - Cancers arising from connective tissue (i.e. bone, cartilage, fat, nerve) • Lymphoma and Leukemia - These two classes of cancer arise from hematopoietic (blood-forming) cells that leave the marrow and tend to mature in the lymph nodes and blood, respectively. CLASSIFICATION
  • 18. • Germ Cell Tumor - Cancers derived from pluripotent cells, most often presenting in the testicle or the ovary (seminoma and dysgerminoma, respectively). • Blastoma - Cancers derived from immature "precursor" cells or embryonic tissue. Blastomas are more common in children than in older adults. CLASSIFICATION
  • 19. • SURGICAL REMOVAL OF CANCER • CHEMOTHERAPHY & RADIATION • WHOLE BODY RADIATION • NANOPARTICLE THERAPY TREATMENT
  • 20. Every satisfactory work is build by means of substantial references. I hereby state to have legitimately exploited following sources in the making of my project- - Guaytton and Sutton’s Textbook of Medicinal Oncology Millenium Edition, © Froth Silk Publishers, Boston - Comprehensive Practical Biology | Class XII A biology practical plus projects textbook by Laxmi Publications Pvt. Ltd. - Wikipedia.com The Online Encyclopedia - ICBSE Online Help Forum http://www.projects.icbse.com/main.aspx - TCYonline.com A world class educational and tutorial site on the web - Meritnation.com REFERENCES