pharmacognosy

2. MARINE PHARMACOGNOSY
Presented By: Josimuddin Biswas
Roll No- 17401916044
Sem- 7th

3. Defination
• Marine pharmacognosy is a sub-branch of
pharmacognosy which is mainly concerned with the
naturally ocurring substances of derived from marine
.Most of the marine drugs are obtained either by
synthesis or from terrestrial organisms.

4. History
 The oceans cover morpharmacognosy e than 70% of the
earthpharmacognosy s surface and rich in fauna and flora.
 Marine pharmacognosy is not a new area for pharmacognosy
even the early civilizations of Greece,Japan ,china and India
have explored marine life as a source of drugs.
 In the western medicinal
Agar,alginicacid,carragreen,protaminesulphate and cod and
halibut liver oils are the marinemedicinal established
procucts.
 Macroalgae or seaweeds have been used as crude drugs in
the treatment of iodine deficiency such as Goiter etc.

6. classification
1.cardiovascular agents.
2.Anticancer agents.
3.Antimicrobial compounds.
4.antibiotic compound.
5.Anti-inflammatory and antisplasmodic
agents

7. Cardiovascular agents
• Eptatraetin
Biological source:Pacific hogfish, viz,Eptatretus
stoutii
use: A potent cardiac stimulant with direct
stimulant action on mammalian myocardium.
• Octopamine
Biological source:Octopus macropus,O.vulgaris
Uses:It produces adrenergic and cardiovascular
responses.

9. Anticancer agents
• Arc-c
Biological source:It is obtained as synthetic
compound in carribean sponges viz, Spongosine
and spongouridine.
Use: used in the treatment of leukemia.
• Crassin acetate
Biological source: It is obtained from carribean
gorgonian.
Use: It is cytotoxic to human leukemia and Hela
cells in vitro.

10. Anti-microbial compound
• Tetrabromothptane
Biological source: Brown algae, Dictyopteris
Zonarodis.
Use: Anti-microbial agents.
• Aeroplysinin-1
Biological source: marine
bacterium,pseudomonas bromutilis.
Use: Antimicrobial agents.

12. Anti-inflammatory and antispasmodic agents
• Manoalide
Biological source: obtained from the
sponge,luffarericella variabilis.
Use: Neurotoxin and also has a rile in synthesis of
prostaglandins in humans.
• Tetradotoxin
Biological source: obtained from liver and ovaries
of puffer fishes.
Use: strong antispasmodic activity.

13. Antibiotic compounds
• 2,4-Dibromo-6-phenol
Biological source:Marine bacterium,pseudom-
monas bromutilis
Use:Antibiotic effect.
• Iracinin-1
Biological source: Iracinia oros
Use: Antibiotic effect