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DR RAKESH K. GUPTA
Vitamins
What do you mean by Vitamins?
 Vitamins are substances that a body needs to grow and
develop normally. These micronutrients are not produced
in our bodies and must be derived from the food.
 Vitamins are earlier supposed to be amines vital for
body and thus were called asVitamine by Casimer
Funk, however, all vitamins are not amines.
 Discovery: first of all by N.I Lunin
 Sir J.C. Drammond called them asVitamin by
dropping the letter “E”.
 Alphabetical nomenclature of vitamins proposed by
Drammond
Types of Vitamins:
Vitamins
Fat soluble
Vitamin A: A1
(Retinol) & A2:
(Dehydroretinol)
Vitamin D:
Calciferol/Cholecalcife
rol/Antiricket/Sun
Shine
Vitamin E:
Beauty/Fertilkity/Anti
sterility
Vitamin K:
napthoquinon/blood
clotting/Phytonadione
water soluble
B1: thiamine/anti beri beri
factor/anti neurotic factor
B2:
riboflavin/Ovoflavin/Vi
tamin /yellow
enzymes/Lactoflavin
Vitamin B3
Pantothenic
acid/yeast factor
vitamin B5
(antipellagra factor/
Niacin/Nicotinic acid)
Vitamin B6(
Pyridoxine)
Vitamin B7 (biotin/vit.
H)
Vitamin B12
(cyanocobalamine/cob
amide cyanide):
Folic acid
(Folaccin/PGA-
Pteroglutamic acid):
Vitamin C (Anti
viral/anti cancer/
ascorbic acid/anti
scurvy/anti rabies
Fat soluble vitamins:
1.Vitamin A (Retinol/antixerothalmic): discovered by Macollum
while isolated by Holmus.
 Derived from kerotene
 Require for normal vision
 Source: mango, cod liver oil, egg, carrot, guava, Beta-carotene
(from plant sources): Leafy, dark green vegetables; dark orange
fruits (apricots, cantaloupe) and vegetables (carrots, winter
squash, sweet potatoes, pumpkin.
 Provide resistance against normal diseases
 Store in liver
 Vitamin A:
 (a) A1: Retinol for vision
 (b) A2: Dehydroretinol: require for epithelium linning and tears
production
Deficiency: vitamin A causes:
 Night blindness/ Nyctolopia/Henrolopia:
deficiency of vit. A1
 Xeropthalamia: vit. A2: cornea get dry and
keratinisation start; tear formation absent;
lead to total blindness
 Keratomalesia: vit. A2; keratinisation follow
by ulcer formation
 Keratinizatioin: takes place in lining of nasal
chamber, trachea and bronchi
 Dermatosis: in this skin become dry like
scales
 Atrophy of the lachrymal glands of the eyes.
Vitamin D:
 Vitamin D/ Calciferol (plant
origin)/cholecalciferol(animal origin) /sunshine
vitamin/antiricket vitamin.
 Regulation absorption of calcium and
phosphorous
 Necessary for bone and teeth formation.
 Deficiency: Rickets in children and Osteomalacia
in adults
 Sources: Egg yolks, liver, fatty fish, fortified milk,
fortified margarine. When exposed to sunlight,
the skin can make vitamin D.
Vitamin E:
 Beauty vitamin/Fertility vitamin/
Antisterility vitamin/Tocopherol.
 Act as antioxidant, reduce the chances of
prostrate and breast cancer.
 Source: Polyunsaturated plant oils (soybean,
corn, cottonseed, safflower); leafy green
vegetables; wheat germ; whole-grain
products; liver; egg yolks; nuts and seeds.
Vitamin K
 Napthoquinon/blood
clotting/Phytonadione):
 Deficiency: Hemorrhagic manifestation, loss
of blood clotting.
 Source: Leafy green vegetables and
vegetables in the cabbage family; milk; also
produced in intestinal tract by bacteria.
Water soluble vitamins:
 Vitamin B1 (Thiamine/ anti beri beri factor/anti
neurotic factor):
 Deficiency: dry beri beri results atrophy and paralysis
of limbs while wet beri beri results loss of weight and
reduce in movement.
 Sources: Found in all nutritious foods in moderate
amounts: pork, whole-grain or enriched breads and
cereals, legumes, nuts and seeds

 Vitamin B2( Riboflavin/Ovoflavin /yellow
enzymes/Lactoflavin):
 Forms coenzymes FAD with phosphoric acid
 Deficiency cause cheilosis where lips become red,
swell and crack appears at the angle of mouth
 Sources: cheese, eggs, milk,liver and yeast.
Vitamin B3 /Pantothenic acid/yeast
factor)
 Deficiency cause burning feet
syndrome.
 Sources: all food including liver
and kidney
Vitamin B5 (Antipellagra factor/
Niacin/Nicotinic acid):
 Deficiency: Pellagra/ 4D syndrome i.e.
dermatitis (redness of skin), diarrhoea,
dementia and death
 sources: Kidney, liver, milk and yeast
Vitamin B6( Pyridoxine)
 Deficiency: Anaemia, nervousness, irritability,
mental disorder and morning disease,
difficulty in walking
 Sources: Meat, fish, poultry, vegetables, fruits
Vitamin B7 (Biotin/Vit. H):
 Deficiency: Muscular pain
 Sources: Widespread in foods; also produced in
intestinal tract by bacteria
Vitamin B12 (cyanocobalamine/cobamide cyanide):
 Deficiency: Perinicious anaemia
 Sources: fish, meat, liver, egg and milk
Folic acid (Folaccin/PGA-Pteroglutamic acid):
 Essential for synthesis of R.B.Cs and DNA.
 Sources: Leafy green vegetables and legumes, seeds,
orange juice, and liver; now added to most refined
grains
 Vitamin C (Anti viral/anti cancer/ ascorbic acid/anti
scurvy/anti rabies):
 Deficiency: Scurvy
 Sources: Tomato, citrus fruits.

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VITAMINS

  • 1. DR RAKESH K. GUPTA Vitamins
  • 2. What do you mean by Vitamins?  Vitamins are substances that a body needs to grow and develop normally. These micronutrients are not produced in our bodies and must be derived from the food.  Vitamins are earlier supposed to be amines vital for body and thus were called asVitamine by Casimer Funk, however, all vitamins are not amines.  Discovery: first of all by N.I Lunin  Sir J.C. Drammond called them asVitamin by dropping the letter “E”.  Alphabetical nomenclature of vitamins proposed by Drammond
  • 3. Types of Vitamins: Vitamins Fat soluble Vitamin A: A1 (Retinol) & A2: (Dehydroretinol) Vitamin D: Calciferol/Cholecalcife rol/Antiricket/Sun Shine Vitamin E: Beauty/Fertilkity/Anti sterility Vitamin K: napthoquinon/blood clotting/Phytonadione water soluble B1: thiamine/anti beri beri factor/anti neurotic factor B2: riboflavin/Ovoflavin/Vi tamin /yellow enzymes/Lactoflavin Vitamin B3 Pantothenic acid/yeast factor vitamin B5 (antipellagra factor/ Niacin/Nicotinic acid) Vitamin B6( Pyridoxine) Vitamin B7 (biotin/vit. H) Vitamin B12 (cyanocobalamine/cob amide cyanide): Folic acid (Folaccin/PGA- Pteroglutamic acid): Vitamin C (Anti viral/anti cancer/ ascorbic acid/anti scurvy/anti rabies
  • 4. Fat soluble vitamins: 1.Vitamin A (Retinol/antixerothalmic): discovered by Macollum while isolated by Holmus.  Derived from kerotene  Require for normal vision  Source: mango, cod liver oil, egg, carrot, guava, Beta-carotene (from plant sources): Leafy, dark green vegetables; dark orange fruits (apricots, cantaloupe) and vegetables (carrots, winter squash, sweet potatoes, pumpkin.  Provide resistance against normal diseases  Store in liver  Vitamin A:  (a) A1: Retinol for vision  (b) A2: Dehydroretinol: require for epithelium linning and tears production
  • 5. Deficiency: vitamin A causes:  Night blindness/ Nyctolopia/Henrolopia: deficiency of vit. A1  Xeropthalamia: vit. A2: cornea get dry and keratinisation start; tear formation absent; lead to total blindness  Keratomalesia: vit. A2; keratinisation follow by ulcer formation  Keratinizatioin: takes place in lining of nasal chamber, trachea and bronchi  Dermatosis: in this skin become dry like scales  Atrophy of the lachrymal glands of the eyes.
  • 6. Vitamin D:  Vitamin D/ Calciferol (plant origin)/cholecalciferol(animal origin) /sunshine vitamin/antiricket vitamin.  Regulation absorption of calcium and phosphorous  Necessary for bone and teeth formation.  Deficiency: Rickets in children and Osteomalacia in adults  Sources: Egg yolks, liver, fatty fish, fortified milk, fortified margarine. When exposed to sunlight, the skin can make vitamin D.
  • 7. Vitamin E:  Beauty vitamin/Fertility vitamin/ Antisterility vitamin/Tocopherol.  Act as antioxidant, reduce the chances of prostrate and breast cancer.  Source: Polyunsaturated plant oils (soybean, corn, cottonseed, safflower); leafy green vegetables; wheat germ; whole-grain products; liver; egg yolks; nuts and seeds.
  • 8. Vitamin K  Napthoquinon/blood clotting/Phytonadione):  Deficiency: Hemorrhagic manifestation, loss of blood clotting.  Source: Leafy green vegetables and vegetables in the cabbage family; milk; also produced in intestinal tract by bacteria.
  • 9. Water soluble vitamins:  Vitamin B1 (Thiamine/ anti beri beri factor/anti neurotic factor):  Deficiency: dry beri beri results atrophy and paralysis of limbs while wet beri beri results loss of weight and reduce in movement.  Sources: Found in all nutritious foods in moderate amounts: pork, whole-grain or enriched breads and cereals, legumes, nuts and seeds   Vitamin B2( Riboflavin/Ovoflavin /yellow enzymes/Lactoflavin):  Forms coenzymes FAD with phosphoric acid  Deficiency cause cheilosis where lips become red, swell and crack appears at the angle of mouth  Sources: cheese, eggs, milk,liver and yeast.
  • 10. Vitamin B3 /Pantothenic acid/yeast factor)  Deficiency cause burning feet syndrome.  Sources: all food including liver and kidney Vitamin B5 (Antipellagra factor/ Niacin/Nicotinic acid):  Deficiency: Pellagra/ 4D syndrome i.e. dermatitis (redness of skin), diarrhoea, dementia and death  sources: Kidney, liver, milk and yeast
  • 11. Vitamin B6( Pyridoxine)  Deficiency: Anaemia, nervousness, irritability, mental disorder and morning disease, difficulty in walking  Sources: Meat, fish, poultry, vegetables, fruits Vitamin B7 (Biotin/Vit. H):  Deficiency: Muscular pain  Sources: Widespread in foods; also produced in intestinal tract by bacteria
  • 12. Vitamin B12 (cyanocobalamine/cobamide cyanide):  Deficiency: Perinicious anaemia  Sources: fish, meat, liver, egg and milk Folic acid (Folaccin/PGA-Pteroglutamic acid):  Essential for synthesis of R.B.Cs and DNA.  Sources: Leafy green vegetables and legumes, seeds, orange juice, and liver; now added to most refined grains  Vitamin C (Anti viral/anti cancer/ ascorbic acid/anti scurvy/anti rabies):  Deficiency: Scurvy  Sources: Tomato, citrus fruits.