A. Sickle-cell anemia Sickle-cell anemia is a genetically inherited trait that is expressed as the synthesis of an abnormal hemoglobin molecule that distorts the rounded shape of red blood cells (to sickle-shaped) and impairs circulation to vital organs. This is an autosomal recessive trait, and therefore the affected individual must have received two copies of the faulty gene (hh), one from each parent. Individuals receiving a faulty gene from one parent and a normal hemoglobin gene from the other parent (Hh) will appear normal but are carriers for the trait and can, therefore, pass it on to their offspring. For each of the following families, fill in the genotypes of the family members near their symbol and then state the probability that the fetus (diamond shape) will express the disease sickle-cell anemia.
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Chapter 7 Pharmacosy Traditional System of Medicine & Ayurvedic Preparations ...
A- Sickle-cell anemia Sickle-cell anemia is a genetically inherited tr.docx
1. A. Sickle-cell anemia Sickle-cell anemia is a genetically inherited trait that is expressed as the
synthesis of an abnormal hemoglobin molecule that distorts the rounded shape of red blood cells
(to sickle-shaped) and impairs circulation to vital organs. This is an autosomal recessive trait,
and therefore the affected individual must have received two copies of the faulty gene (hh), one
from each parent. Individuals receiving a faulty gene from one parent and a normal hemoglobin
gene from the other parent (Hh) will appear normal but are carriers for the trait and can,
therefore, pass it on to their offspring. For each of the following families, fill in the genotypes of
the family members near their symbol and then state the probability that the fetus (diamond
shape) will express the disease sickle-cell anemia.
