Let's know something interesting about sickle cell anemia.
May be you, understand it better affter viewing this slide.
you can find everything (like- History, Etiology, Complications etc.)about SCA.
I hope, you will like it.
A group of disorders that cause red blood cells to become misshapen and break down.
With sickle cell disease, an inherited group of disorders, red blood cells contort into a sickle shape. The cells die early, leaving a shortage of healthy red blood cells (sickle cell anaemia) and can block blood flow causing pain (sickle cell crisis).
Infections, pain and fatigue are symptoms of sickle cell disease.
Treatments include medication, blood transfusions and rarely a bone-marrow transplant
Leukemia disease is a cancer of the blood-forming tissues. Most of the time, it is a cancer of the white blood cells, but some leukemia’s start in other kinds of blood vessels.
Sickle cell anemia is a genetic diseases where red blood cells can take shape of a crescent or a sickle . And this allows them to be more easily destroyed – causing anemia and other complexities
A group of disorders that cause red blood cells to become misshapen and break down.
With sickle cell disease, an inherited group of disorders, red blood cells contort into a sickle shape. The cells die early, leaving a shortage of healthy red blood cells (sickle cell anaemia) and can block blood flow causing pain (sickle cell crisis).
Infections, pain and fatigue are symptoms of sickle cell disease.
Treatments include medication, blood transfusions and rarely a bone-marrow transplant
Leukemia disease is a cancer of the blood-forming tissues. Most of the time, it is a cancer of the white blood cells, but some leukemia’s start in other kinds of blood vessels.
Sickle cell anemia is a genetic diseases where red blood cells can take shape of a crescent or a sickle . And this allows them to be more easily destroyed – causing anemia and other complexities
Sickle cell anemia is one of a group of inherited disorders known as sickle cell disease.
It affects the shape of red blood cells, which carry oxygen to all parts of the body.
Sickle Cell disease: is a genetic disorder that affects erythrocytes (RBC) causing them
to become sickle or crescent shaped.
The effects of this condition due to an abnormality of the hemoglobin molecules found
in erythrocytes.
Sickle cell anemia is a serious disease in which the body makes sickle-shaped red blood
cells. “Sickle-shaped” means that the red blood cells are shaped like a "C."
Normal red blood cells are disc-shaped and look like doughnuts without holes in the
center. They move easily through your blood vessels. Red blood cells contain the
protein hemoglobin. This iron-rich protein gives blood its red color and carries oxygen
from the lungs to the rest of the body.
Sickle cell Anemia is known as being a fatal hereditary form of anemia, it is recognized
by its abnormal red blood cells having a crescent shape due to the effect of hemoglobin
S found in the cells.
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4. It is a genetic disorder that affects red
blood cells causing them to become
sickle shaped.
RBCs aren’t enough healthy to carry
adequate oxygen throughout body.
It is due to abnormal hemoglobin.
5. Discribed in 1910 by Dr. James Herrick
In 1917 – Genetic basis for SCD by Dr. V. Emmel
In 1922 - Dr. V.R Mason names the disease Sickle Cell
Anemia.
Autosomal recessive disorder.
Arise from a mutation in Hb-gene
Normally, human RBCs are flexible & round moving easily
through blood vessels. But in this case it become sickle
shaped, irregular, sticky & rigid that’s why it also sticks
with blood vessel
6.
7.
8. If one parent has sickle
cell anemia trait
(HbAS) and the other
has sickle cell anemia
(HbSS) then there is
50% chances of any
given child will get
sickle cell anemia
In this case, no child
will be compelety
unaffected
9. If both parents have
sickle cell trait (HbAS)
then there will only
25% chances to be
child with sickle cell
anemia
25% child will be
totally normal
And other 50% with
sickle cell anemia trait
10.
11. There are some symptoms of SCA
•Anemia
•Periodic pain
• Painful swelling of hands and feet
•Frequent infection
•Delayed growth
•Vision problem
12. SCA can lead to host of complications, such as:
• Organ Damage
• Leg ulcer
• Blindness
• Gallstones
• Acute chest syndrome
• Pulmonary hypertension
• stroke
