Antibiotic resistant bacteria

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Antibiotic resistant bacteria

  1. 1. What doesn’t kill them makesthem stronger
  2. 2. Discovers penicillin in1928
  3. 3. • The invention of early antibiotics, namely penicillin, provided a huge advance in the treatment of infectious diseases. Antibiotics have turned many would-be fatal conditions into manageable ailments. With this success has come an overreliance on antibiotics as a fix for every cough and sniffle. This opens a Pandoras box of medical pitfall
  4. 4. • As early as 1946, scientists (including A. Fleming) were warning of the possible dangers of antibiotic-resistant bacteria• A few bacteria in populations that have never been exposed to artificial antibiotics probably carry alleles that give resistance to antibiotics• Resistance alleles can also arise by mutation• Resistant bacteria can use a number of mechanisms to overcome antibiotics
  5. 5. One of the biggest problems with the overuse ofantibiotics is an acquired resistance to the drug bythe infecting bugs. Antibiotics act on bacteria whichhave the ability to adapt to a variety of situationsand learn ways around the killing mechanisms ofvarious antibiotics. If one of several types of bacteriais exposed to the same or similar antibiotics, thesebugs can learn to outlive the effects of the drugs.The World Health Organization has stated that drugresistance is one of the major problems we facetoday [Source: WHO]. Some bacteria, like MRSA(methicillin resistant staph aureus) are referred to bythe drug they can resist.
  6. 6. • Antibiotic use represents a strong selection pressure• If a population of bacteria with a few resistant individuals is exposed to a lethal antibiotic, the susceptible bacteria will die, but the resistant bacteria will survive• In an environment with a lot of antibiotic use, resistance alleles spread rapidly• The problem is compounded by horizontal gene transfer and by cross-resistance
  7. 7. • Bacteria have the ability to acquire genes from other bacterium without being its offspring.• http://www.youtube.com/watch?feature=player_detailpag e&v=eRvfhljxA4s
  8. 8. • Many of the most widely used antimicrobial drugs are already ineffective• Pharmaceutical companies cannot create new drugs fast enough to treat drug resistant bacteria• Reduce inappropriate prescription of antibiotics• Reduce inappropriate prescription of antibiotics • Increase public awareness that many diseases cannot be cured with antibiotics• Reduce use of agricultural antibiotics• Increase the number of patients who finish their courses of antibiotics• Restrict the use of new antibiotics• Reduce use of agricultural antibiotics• Increase the number of patients who finish their courses of antibiotics• Restrict the use of new antibiotics• http://www.youtube.com/watch?feature=player_detailpage&v=UZatOI Wlf3Y

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