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Dr. Jayesh V Patidar
www.drjayeshpatidar.blogspot.com

1
1. Susceptible patient:Many patients in
hospital have impaired
defense mechanism
due to pre-existing
disease, such as
diabetes, immunosuppression & patients
with prosthetic implants.
They are, therefore
more susceptible to
infection.
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2
2. Hospital
Environment:Pathogens may be
present in
air, dust, water, food
or antiseptic lotion.
Equipment may be
contaminated.
Bedding, linen &
utensils may act as
fomites. Patients
shed the organisms
from their bodies
while hospital
personnel spread
these organisms

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3. Diagnostic or therapeutic procedures:During diagnostic or
therapeutic
procedures such as
insertion of urethral or
intravenous
catheters, the
slightest
lapse in asepsis may
lead to infection.
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4. Drug Resistance:-

Hospital infections
are generally
refractory to
treatment as the
infecting agents
are usually multidrug resistant.

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5. Transfusion:Blood, blood products
& intravenous fluids
used for
transfusion, if not
properly
screened, can
transmit many
infections.
Blood, blood
products &
intravenous fluids
used for
transfusion, if not
properly
screened, can

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6
6. Advances in medical progress:-

Advances in
treatment of
cancer, organ
transplantation,
implanted
prostheses &
other
sophisticated
technologies
enhance the risk
of infection.
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

Esch. Coli, Klebsiella, Enterobacter, proteus &
Serratia have become the most important
hospital pathogens, particularly because of
dissemination among them of R factor
conferring multiple drug resistance.



Pseudomonas aeruginosa & other
pseudomonas species have always been
important hospital pathogens because of their
intrinsic resistance to most antibiotics & ability
to survive & even multiply in disinfectants
solutions.
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8


Tetanus spores can survive in dust & may
sometimes contaminate items used in hospital.
Hospital tetanus is usually due to faulty
sterilization techniques or other lapses in
asepsis.



HIV & hepatitis B & C viruses are transmitted
by contaminated blood & blood products.



Virus diarrhea & chickenpox may spread in
hospitals. Cytomegalovirus, influenza, herpes
virus, enterovirus are some other virus which
may cause hospital infection.
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1. Contact:a) Hands or clothing:Hands or
hospital staff are an
important vehicle of
spread of infection. There
is adequate scope of
transmission of
microorganisms from one
person to another by
contact of hands and
clothing of attendants.
Staphylococcus aureus
and streptococcus
pyogenes are two

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10
b) Inanimate objects :Certain instruments
(endoscope, bronc
hoscope, cystoscop
e), if not property
disinfected, may
transmit pathogenic
organisms (eg:pseudomonas
aeruginosa)

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11
2. Airborne:a) Droplets:Droplets of respiratory infection is transmitted
by inhalation.
b) Dust:Dust from bedding , floors, exudates dispersed
from a wound during dressing & from skin by natural
shedding of skin scales (measles, staphylococcal
sepsis), may contribute in spread in of infection eg:.
Pseudomonas aeruginosa, staph. aureus.
c) Aerosols:Aerosols produced by nebulizers, humidifiers
& air conditioning apparatus transmit certain
pathogens to the respiratory tract occurrence of
legionellae in hospital water supply has lead to out
12
breaks of infections mainly 12/26/2013 legionella
with www.drjayeshpatidar.blogspot.com
3. Oral Route:Hospital food may contain antibiotic-resistant
bacteria (pseudomonas aeruginosa, Esch.
Coli, klebsiella spp. & others ), which may colonize
the intestine & later cause infection in susceptible
patients.
4. Parenteral Route:With the introduction of disposable
syringes & needles, transmission of infection by
parenteral route has been infrequent. Certain
infection may be transmitted by blood transfusion or
tissue donation, contaminated blood products
(Factor VIII) & contaminated infusion fluid. Hepatitis
B & HIV are two viruses which may be transmitted in
12/26/2013 www.drjayeshpatidar.blogspot.com
13
this way.
Toys and Transmission of
infection:Playing
together & sharing of contribute to
the child’s development of social
skill. Toys may be considered as a
part of the equipment of a
pediatrics unit, but sharing of toys
poses a potential health risk.
Microbial contaminated of toys has
been documented in
hospital, pediatrician offices & day
care centre. Fecal coli forms &
rotavirus have been found on toys
12/26/2013
in day care centre & in hospital. www.drjayeshpatidar.blogspot.com

14
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15
1. Urinary Tract Infection:This is
usually associated with
catheterization or
instrumentation of
urethra, bladder or kidney.
Infection is caused by Esch.
Coli, Klebsiella, proteus, serr
atia
pseudomonas, providencia, c
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16
2. Respiratory Infection:Aspiration in
unconscious patients & pulmonary ventilation
may lead to nosocomial pneumonia. The major
pathogens include staph.
aureus, klebsiella, enterobactor
, serratia, proteus, Esch. Colli, pseudomonas
aeruginosa, acinetobacter & respiratory
viruses.

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17
3.

Wound and skin sepsis:-

Aspiration in unconscious
patients & pulmonary
ventilation may lead to
nosocomial pneumonia.
The major pathogens
include staph.
aureus, klebsiella, enter
obactor
, serratia, proteus, Esch
. Colli, pseudomonas
aeruginosa, acinetobact
er & respiratory viruses.
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18
5.

Gastrointestinal Infections:Food poisoning &
neonatal septicemia in hospital have been
reported. Salmonella & sligella sonnei are
mainly associated with these infections.

6.

Burns:Staph. aureus, pseudomonas
aeruginosa, acinetobacter & str. Pyogenes are
responsible for hospital acquired infections in
cases of burns.
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19
6.

Bacteraemia and septicemia:These may be
consequences of infection at any site but are
generally caused by infected intravenous
canula. Gram negative bacilli are common
pathogens. Intravenous rehydration in diarrhea
should be replaced by oral fluids as early as
possible.
Staph. epidermidis bacteraemia is
found commonly in patients with artificial heart
valve. Bacteraemia in those with valular defects
may lead to endocarditis.
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20
Hospital acquired infection may occur
sporadically or as out breaks. Diagnosis is by the
routine bacteriological methods such as direct smear
examination, from possible sources of infection such
as hospital personal, inanimate objects water, air or
food. Typing of isolate (phage typing bacteriocin
typing, biotyping or autibiogram) may indicate a
causal connection.

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21
control of hospital infection should be a
permanent ongoing activity. Examples of sources of
hospital out breaks are nasal carriage of staphylococci
in hospital staff or pseudomonas growing in lotions.
Carriers should be suitably treated.
The cause of infection may be a
defective autoclave, therefore, sterilization techniques
have to be tested.
This may lead to selected colonization
by multi-resistant pathogens & has a harmful effect.

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22
Administration of antibiotic therapy to the carrier
staff or source patient to destroy the pathogenic
agents.
 Proper sterilization & disinfection of the
inanimate objects should be done . this helps to
control the source of infection.
 Disinfection of excreta & infection material is
necessary to control the exit point of infection.
 Transmission of infection can be controlled by
regular washing of hand, disinfection of
equipments & change of working clothes.


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23
•The use of sterile dressing, surgical gloves,
face-marks & I/V fluids further contribute in
control of infection.
•Preoperative disinfection of the patient’s skin.
•Rational antibiotics prophylaxis.
•Cleaning of toys :-Toys used by infants & young children
should optimally be cleaned between use
by different patient.
-Disinfect with 1:1000 bleach
solution, wash soap &water & air dry.
•Proper investigation of hospital – acquired
infection & the treatment of such cases.
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24
Every hospital must have an
effective hospital – acquired infection control
committee (HAICC) which should be
responsible for the control of hospital –acquired
infection (HAI). The committee should be
chaired be medical superintendent & should
have of all clinical departments, blood
bank, microbiologist, medical record
officer, chief of nursing services & infection
control sister as members. Chief of all the
supportive services
(O.T, dietetics, laundry, house keeping etc. )
12/26/2013

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25
HAICC must meet at least once
every mouth to formulate & update policy on matters
related to hospital infection & to manage outbreaks of
hospital acquired infection. The committee will review
infection control activities of the hospital, emergency
of drug resistance, use of different antimicrobial
agent, sterilization& disinfection procedures, hospital
environment, incidence & type of infection &
antimicrobial sensitivity patterns of the prevent
pathogens.

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26
Nurse caring for young children are frequently
in contact with body substances, especially
urine, feces, & vomits. Nurse need to exercise
judgment for those situation when gloves, gown
or masks are necessary.
 During feedings, gowns should be worn if the
child is likely to vomit or spit up, which often
occurs during burping. When gloves are
worn, the hands are washed thoroughly after
removing the gloves, because both latex & vinyl
gloves fail to provide complete protection.


12/26/2013

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27
•All needles (uncapped & unbroken) are
disposed of in a rigid, puncture – resistant
container located near the site of use.
•Nurse should follow standard precaution for
the car of children’s.

12/26/2013

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28
Q.

Explain the nursing responsibility
regarding the prevention of
nosocomial infection in pediatric

unit.

12/26/2013

www.drjayeshpatidar.blogspot.com

29
1.

2.

3.

4.

David wilson Ms. Etal. Nursing care of infants
& children. 7th editions. Mosby publication
(2006).
P. No. 1334-1336.
Parul Datta. . Pediatric nursing. 1st
edition(2007) Jaypee brothers publication.
New Delhi. P. No. 3-7.
O.P. Ghai. Essential pediatrics. 6th edition
(2004). Published by Dr. Ghai New Delhi.P.
No. 668-670.
RL Ichhpujani, Rajesh Bhatia. Microbilogy for
Nurses. 2nd edition (2003), Jaypee publication
New Delhi. P. No. 198-200.
12/26/2013

www.drjayeshpatidar.blogspot.com

30
12/26/2013

www.drjayeshpatidar.blogspot.com

31

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Nosocomial infection

  • 1. Dr. Jayesh V Patidar www.drjayeshpatidar.blogspot.com 1
  • 2. 1. Susceptible patient:Many patients in hospital have impaired defense mechanism due to pre-existing disease, such as diabetes, immunosuppression & patients with prosthetic implants. They are, therefore more susceptible to infection. 12/26/2013 www.drjayeshpatidar.blogspot.com 2
  • 3. 2. Hospital Environment:Pathogens may be present in air, dust, water, food or antiseptic lotion. Equipment may be contaminated. Bedding, linen & utensils may act as fomites. Patients shed the organisms from their bodies while hospital personnel spread these organisms 12/26/2013 www.drjayeshpatidar.blogspot.com 3
  • 4. 3. Diagnostic or therapeutic procedures:During diagnostic or therapeutic procedures such as insertion of urethral or intravenous catheters, the slightest lapse in asepsis may lead to infection. 12/26/2013 www.drjayeshpatidar.blogspot.com 4
  • 5. 4. Drug Resistance:- Hospital infections are generally refractory to treatment as the infecting agents are usually multidrug resistant. 12/26/2013 www.drjayeshpatidar.blogspot.com 5
  • 6. 5. Transfusion:Blood, blood products & intravenous fluids used for transfusion, if not properly screened, can transmit many infections. Blood, blood products & intravenous fluids used for transfusion, if not properly screened, can 12/26/2013 www.drjayeshpatidar.blogspot.com 6
  • 7. 6. Advances in medical progress:- Advances in treatment of cancer, organ transplantation, implanted prostheses & other sophisticated technologies enhance the risk of infection. 12/26/2013 www.drjayeshpatidar.blogspot.com 7
  • 8.  Esch. Coli, Klebsiella, Enterobacter, proteus & Serratia have become the most important hospital pathogens, particularly because of dissemination among them of R factor conferring multiple drug resistance.  Pseudomonas aeruginosa & other pseudomonas species have always been important hospital pathogens because of their intrinsic resistance to most antibiotics & ability to survive & even multiply in disinfectants solutions. 12/26/2013 www.drjayeshpatidar.blogspot.com 8
  • 9.  Tetanus spores can survive in dust & may sometimes contaminate items used in hospital. Hospital tetanus is usually due to faulty sterilization techniques or other lapses in asepsis.  HIV & hepatitis B & C viruses are transmitted by contaminated blood & blood products.  Virus diarrhea & chickenpox may spread in hospitals. Cytomegalovirus, influenza, herpes virus, enterovirus are some other virus which may cause hospital infection. 12/26/2013 www.drjayeshpatidar.blogspot.com 9
  • 10. 1. Contact:a) Hands or clothing:Hands or hospital staff are an important vehicle of spread of infection. There is adequate scope of transmission of microorganisms from one person to another by contact of hands and clothing of attendants. Staphylococcus aureus and streptococcus pyogenes are two 12/26/2013 www.drjayeshpatidar.blogspot.com 10
  • 11. b) Inanimate objects :Certain instruments (endoscope, bronc hoscope, cystoscop e), if not property disinfected, may transmit pathogenic organisms (eg:pseudomonas aeruginosa) 12/26/2013 www.drjayeshpatidar.blogspot.com 11
  • 12. 2. Airborne:a) Droplets:Droplets of respiratory infection is transmitted by inhalation. b) Dust:Dust from bedding , floors, exudates dispersed from a wound during dressing & from skin by natural shedding of skin scales (measles, staphylococcal sepsis), may contribute in spread in of infection eg:. Pseudomonas aeruginosa, staph. aureus. c) Aerosols:Aerosols produced by nebulizers, humidifiers & air conditioning apparatus transmit certain pathogens to the respiratory tract occurrence of legionellae in hospital water supply has lead to out 12 breaks of infections mainly 12/26/2013 legionella with www.drjayeshpatidar.blogspot.com
  • 13. 3. Oral Route:Hospital food may contain antibiotic-resistant bacteria (pseudomonas aeruginosa, Esch. Coli, klebsiella spp. & others ), which may colonize the intestine & later cause infection in susceptible patients. 4. Parenteral Route:With the introduction of disposable syringes & needles, transmission of infection by parenteral route has been infrequent. Certain infection may be transmitted by blood transfusion or tissue donation, contaminated blood products (Factor VIII) & contaminated infusion fluid. Hepatitis B & HIV are two viruses which may be transmitted in 12/26/2013 www.drjayeshpatidar.blogspot.com 13 this way.
  • 14. Toys and Transmission of infection:Playing together & sharing of contribute to the child’s development of social skill. Toys may be considered as a part of the equipment of a pediatrics unit, but sharing of toys poses a potential health risk. Microbial contaminated of toys has been documented in hospital, pediatrician offices & day care centre. Fecal coli forms & rotavirus have been found on toys 12/26/2013 in day care centre & in hospital. www.drjayeshpatidar.blogspot.com 14
  • 16. 1. Urinary Tract Infection:This is usually associated with catheterization or instrumentation of urethra, bladder or kidney. Infection is caused by Esch. Coli, Klebsiella, proteus, serr atia pseudomonas, providencia, c 12/26/2013 www.drjayeshpatidar.blogspot.com 16
  • 17. 2. Respiratory Infection:Aspiration in unconscious patients & pulmonary ventilation may lead to nosocomial pneumonia. The major pathogens include staph. aureus, klebsiella, enterobactor , serratia, proteus, Esch. Colli, pseudomonas aeruginosa, acinetobacter & respiratory viruses. 12/26/2013 www.drjayeshpatidar.blogspot.com 17
  • 18. 3. Wound and skin sepsis:- Aspiration in unconscious patients & pulmonary ventilation may lead to nosocomial pneumonia. The major pathogens include staph. aureus, klebsiella, enter obactor , serratia, proteus, Esch . Colli, pseudomonas aeruginosa, acinetobact er & respiratory viruses. 12/26/2013 www.drjayeshpatidar.blogspot.com 18
  • 19. 5. Gastrointestinal Infections:Food poisoning & neonatal septicemia in hospital have been reported. Salmonella & sligella sonnei are mainly associated with these infections. 6. Burns:Staph. aureus, pseudomonas aeruginosa, acinetobacter & str. Pyogenes are responsible for hospital acquired infections in cases of burns. 12/26/2013 www.drjayeshpatidar.blogspot.com 19
  • 20. 6. Bacteraemia and septicemia:These may be consequences of infection at any site but are generally caused by infected intravenous canula. Gram negative bacilli are common pathogens. Intravenous rehydration in diarrhea should be replaced by oral fluids as early as possible. Staph. epidermidis bacteraemia is found commonly in patients with artificial heart valve. Bacteraemia in those with valular defects may lead to endocarditis. 12/26/2013 www.drjayeshpatidar.blogspot.com 20
  • 21. Hospital acquired infection may occur sporadically or as out breaks. Diagnosis is by the routine bacteriological methods such as direct smear examination, from possible sources of infection such as hospital personal, inanimate objects water, air or food. Typing of isolate (phage typing bacteriocin typing, biotyping or autibiogram) may indicate a causal connection. 12/26/2013 www.drjayeshpatidar.blogspot.com 21
  • 22. control of hospital infection should be a permanent ongoing activity. Examples of sources of hospital out breaks are nasal carriage of staphylococci in hospital staff or pseudomonas growing in lotions. Carriers should be suitably treated. The cause of infection may be a defective autoclave, therefore, sterilization techniques have to be tested. This may lead to selected colonization by multi-resistant pathogens & has a harmful effect. 12/26/2013 www.drjayeshpatidar.blogspot.com 22
  • 23. Administration of antibiotic therapy to the carrier staff or source patient to destroy the pathogenic agents.  Proper sterilization & disinfection of the inanimate objects should be done . this helps to control the source of infection.  Disinfection of excreta & infection material is necessary to control the exit point of infection.  Transmission of infection can be controlled by regular washing of hand, disinfection of equipments & change of working clothes.  12/26/2013 www.drjayeshpatidar.blogspot.com 23
  • 24. •The use of sterile dressing, surgical gloves, face-marks & I/V fluids further contribute in control of infection. •Preoperative disinfection of the patient’s skin. •Rational antibiotics prophylaxis. •Cleaning of toys :-Toys used by infants & young children should optimally be cleaned between use by different patient. -Disinfect with 1:1000 bleach solution, wash soap &water & air dry. •Proper investigation of hospital – acquired infection & the treatment of such cases. 12/26/2013 www.drjayeshpatidar.blogspot.com 24
  • 25. Every hospital must have an effective hospital – acquired infection control committee (HAICC) which should be responsible for the control of hospital –acquired infection (HAI). The committee should be chaired be medical superintendent & should have of all clinical departments, blood bank, microbiologist, medical record officer, chief of nursing services & infection control sister as members. Chief of all the supportive services (O.T, dietetics, laundry, house keeping etc. ) 12/26/2013 www.drjayeshpatidar.blogspot.com 25
  • 26. HAICC must meet at least once every mouth to formulate & update policy on matters related to hospital infection & to manage outbreaks of hospital acquired infection. The committee will review infection control activities of the hospital, emergency of drug resistance, use of different antimicrobial agent, sterilization& disinfection procedures, hospital environment, incidence & type of infection & antimicrobial sensitivity patterns of the prevent pathogens. 12/26/2013 www.drjayeshpatidar.blogspot.com 26
  • 27. Nurse caring for young children are frequently in contact with body substances, especially urine, feces, & vomits. Nurse need to exercise judgment for those situation when gloves, gown or masks are necessary.  During feedings, gowns should be worn if the child is likely to vomit or spit up, which often occurs during burping. When gloves are worn, the hands are washed thoroughly after removing the gloves, because both latex & vinyl gloves fail to provide complete protection.  12/26/2013 www.drjayeshpatidar.blogspot.com 27
  • 28. •All needles (uncapped & unbroken) are disposed of in a rigid, puncture – resistant container located near the site of use. •Nurse should follow standard precaution for the car of children’s. 12/26/2013 www.drjayeshpatidar.blogspot.com 28
  • 29. Q. Explain the nursing responsibility regarding the prevention of nosocomial infection in pediatric unit. 12/26/2013 www.drjayeshpatidar.blogspot.com 29
  • 30. 1. 2. 3. 4. David wilson Ms. Etal. Nursing care of infants & children. 7th editions. Mosby publication (2006). P. No. 1334-1336. Parul Datta. . Pediatric nursing. 1st edition(2007) Jaypee brothers publication. New Delhi. P. No. 3-7. O.P. Ghai. Essential pediatrics. 6th edition (2004). Published by Dr. Ghai New Delhi.P. No. 668-670. RL Ichhpujani, Rajesh Bhatia. Microbilogy for Nurses. 2nd edition (2003), Jaypee publication New Delhi. P. No. 198-200. 12/26/2013 www.drjayeshpatidar.blogspot.com 30