Aloe Vera as a nutraceutical Content Introduction of Aloe Vera name family origin botanical name Introduction to nutraceutical History of nutraceutical and aloe Vera Nutritional composition Cultivation method of aloe vera Varieties of products in aloe vera health benefits of aloe vera advantages and disadvantages of aloe vera conclusion

1. Aloe vera as a nutraceutical
Ansari Sana
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2. Content:
Introduction
History
Nutritional composition of aloe Vera
Cultivation
Various products of Aloe Vera
Health Benefit
Advantages And Disadvantages Of Aloe vera
Conclusion
Reference
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3. Introduction:
Aloe vera a well-known plant grows in semi-arid climate of tropical and subtropical regions. The Aloe vera plant has been known and used
for centuries for its health, beauty, medicinal and skin care properties. The name Aloe vera derives from the Arabic word “Alloeh”
meaning “shining bitter substance,” while “vera” in Latin means “true.” 2000 years ago, the Greek scientists regarded Aloe vera as the
universal panacea. The Egyptians called Aloe “the plant of immortality.” Today, the Aloe vera plant has been used for various purposes in
dermatology. Aloe vera well known for its nutraceutical potential, is being explored as a functional ingredient in a wide array of health
foods and drinks.
Aloe vera constituents as dietary nutraceutical, medicinal, and therapeutic potential. Plant is cultivated for agricultural and medicinal and
decoration purposes for indoors as a potted plant. Plant is a good depository of chemical constituents which display a very wide array of
biological activities such as anticancer, antiparasitic, antidiabetic, anti- inflammatory, anti-arthritic, antiparasitic, antitumor, antioxidant,
chemo preventive, hepatoprotective, and gastroprotective. Plant is used to prepare skin protective/care gels mainly for soothing,
moisturizing, and wound healing. Thick watery plant sap works are added as key ingredient in many beauty products. Plant leaves are used
to generate aroma, beverages, skin lotion, cosmetics, or ointments for minor burns. Plant contains vitamins, enzymes, minerals, sugars,
lignin, saponins, salicylic acids, and amino acids as main ingredients. Plant is a good source of Vitamins A, C, and E, which are
antioxidants. It also contains Vitamin B12, folic acid, and choline watery juicy of A. vera leaf which contains important minerals such as
calcium, chromium, copper, selenium, magnesium, manganese, and potassium. Plant ingredients were found active against gingivitis,
psoriasis, and used for herbal therapy in inflammatory bowel disease. A. vera contains important fatty acids mainly steroids such as
cholesterol, campestral, β-sitosterol, and lupeol. Aloin and emodin act as analgesics, antibacterial, and antivirals while lupeol shows
antiseptic and analgesic properties. It also contains auxins and gibberellin hormones that help in wound healing and have anti-
inflammatory action. Saponins that are the soapy substances display cleansing and antiseptic properties.
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4. Scientific Name
Botanical name
Subfamily
Family : Liliaceae
: Aloe Barbadensis
:Aloe Vera
:AsaphodeloideaeGenus
:
Species : A. Vera (300)
:Angiosperms
Origin : In India Maharashtra, Gujarat, Tamilnadu.
Aloe vera has 400 different species.
Aloe vera is commonly known as Ghritkumari, Kunwarpathu.
Aloe vera plant contain 95% water.
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5.  NEUTRACEUTICALS:
 Definition-A food or part of food or nutrient, that provides health benefits, including the prevention and
treatment of a disease is known as Nutraceuticals
Aloe vera has been used for centuries and is presently widely exploited as a nutraceutical. It is available in the
form of various health drinks and formulations such as capsules/ tablets or externally in the form of gels &
creams. Being a potent immunomodulator, it can be used in various ailments as a single drug or in a combination
therapy. The area of formulation research is lacking in understanding the correlation of unique active therapeutic
agent acemannan - a glucomannan present in aloe vera and its dose, due to numerous physical, microbiological
and biochemical factors interfering in the extraction/ processing of aloe vera juice. Studies are limited and
generally becoming complicated because of not having ability to discriminate between different species, since a
very few species have a therapeutic effectiveness amongst about 400 species of aloe vera found worldwide. Being
sensitive to heat, enzymes and shock, it is a good subject for formulation researchers as there is a concern about
aloe products having a little or no aloe in them. The current article is about chemistry of aloe vera in exploring its
potential as a mainstay of chronic drug therapy.

6. History:
The 1st note of aloe vera found on the Sumeran clay tablet in 2100 B.C. Aloe vera also known as “ Lily of the desert” and considered
the “plant of immortality” by many native peoples. Introduced to china and various part of southern Europe in the 4th century. Aloe vera
has been used for medicinal purposes in several cultures for millennia: Greece, Egypt, India, Mexico, Japan and China. Egyptian queens
Nefertiti and Cleopatra used it as part of their regular beauty regimes. Alexander the Great, and Christopher Columbus used it to treat
soldiers’ wounds. The first reference to Aloe vera in English was a translation by John Goodyew in A.D. 1655 of Dioscorides Medical
treatise De Materia Medica. By the early 1800s, Aloe vera was in use as a laxative in the United States, but in the mid-1930s, a turning
point occurred when it was successfully used to treat chronic and severe radiation dermatitis.
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7. Nutritional composition:
Active components with its properties:
Aloe leaf contains over 240 nutritional and medicinal ingredients, including vitamins, minerals, enzymes, sugars, lignin,
saponins, sterols, amino acids, salicylic acid, etc.
1. Vitamins: It contains vitamins A (beta-carotene), C and E, which are antioxidants. It also contains vitamin B12, folic acid, and choline. Antioxidant neutralizes free
radicals.
2. Enzymes: It contains 8 enzymes: aliiase, alkaline phosphatase, amylase, bradykinase, carboxypeptidase, catalase, cellulase, lipase, and peroxidase. Bradykinase helps to
reduce excessive inflammation when applied to the skin topically, while others help in the breakdown of sugars and fats.
3. Minerals: It provides calcium, chromium, copper, selenium, magnesium, manganese, potassium, sodium and zinc. They are essential for the proper functioning of various
enzyme systems in different metabolic pathways and few are antioxidants.
4. Sugars: It provides monosaccharides (glucose and fructose) and polysaccharides:
(glucomannans/polymannose). These are derived from the mucilage layer of the plant and are known as mucopolysaccharides. The most prominent monosaccharide is
mannose-6- phosphate, and the most common polysaccharides are called glucomannans [beta-(1,4)- acetylated mannan]. Acemannan, a prominent glucomannan has also
been found. Recently, aglycoprotein with antiallergic properties, called alprogen and novel anti-inflammatory compound, C-glucosyl chromone, has been isolated from Aloe
vera gel.
5. Anthraquinones: It provides 12 anthraquinones, which are phenolic compounds
traditionally known as laxatives. Aloin and emodin act as analgesics, antibacterials and antivirals.
6. Fatty acids: It provides 4 plant steroids; cholesterol, campesterol, β-sisosterol and lupeol. All these have anti-inflammatory action and lupeol also possesses antiseptic and
analgesic
properties.
7. Hormones: Auxins and gibberellins that help in wound healing and have anti-inflammatory action.
8. Others: It provides 20 of the 22 human required amino acids and 7 of the 8 essential amino
acids. It also contains salicylic acid that possesses anti-inflammatory and antibacterial properties. Lignin, an inert substance, when included in topical preparations, enhances
penetrative effect of the other ingredients into the skin. Saponins that are the soapy substances form about 3% of the gel and have cleansing and antiseptic properties.

8. Cultivation:
Climate required:-
 Basically warm tropical crop.
 Grown in low rainfall and dry area .
 It can not tolerate cool climatic condition.
Soil requirement:-
 Cultivated on sandy soils.
 Grown in light soil.
 pH range up to 8.5.
 Tolerate to salty soil.
Propagation / Planting Method:-
 Done through root suckers/rhizome cutting.
Directly planted in main land.
Rhizomes cut about 6 cm.
Land preparation:-
 Should be ploughed
 To increase soil fertility add 15 to 20 tonnes of rotten.
Planting density:-
To accommodate about 50,000 to 55,000 plant per hectare
Space maintain 40 × 45 cm.
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9. Land preparation:-
Should be ploughed
To increase soil fertility add 15 to 20 tones of rotten.
Planting density:-
To accommodate about 50,000 to 55,000 plant per hectare
Space maintain 40 × 45 cm.
Irrigation:-
It can be grown both rainfall and irrigated condition
Weed control:-
Weeding should be done at regular interval.
Pest and Diseases control:-
As basal dose, fertilizer like NPK in ratio 50:50:50 kg/hectare.
Harvesting:-
Ready for harvesting from 2nd yr after planting.
Fresh leaves of 3 or 4 can be picked.
Regenerate up to 5 yrs.
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10. Various product of Aloe vera:
Aloe vera juice
Aloe vera concentrate
Aloe vera pickle
Aloe vera gel
Aloe powder
Cosmetic products such as soap, creams , gel, spray ,handwash, lotions
Aloe vera yoghurt.
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11. HEALTH BENEFITS
1.Digestive Benefits-
Aloe vera juice help to decrease inflammation, colitis and other inflammatory disorders of the gut.
1.Heart benefits-
improve blood circulation in the body, reduce fatty deposits and blood clots
in the arteries of the heart and body, stabilize heart rhythm
3.Immune System Benefits-
Aloe vera contains antibacterial, Anti-viral and anti-fungal properties that aid the immune system and helps to cleanse the body toxins and
invading pathogens and helps in treatment of inflammatory immune disorders.
3.Medicinal uses-
The plant is used widely in the traditional herbal medicine of many countries. Despite this, the cosmetic and alternative medicine
industries regularly make
claims regarding the soothing, moisturizing, and healing properties of A. vera. Aloe juice and gel provide protection for humans from
sunburn A. vera gel is used commercially as an ingredient in yogurts, beverages, and some desserts, although at certain doses, its toxic
properties could be severe whether ingested or topically applied. The same is true for aloe latex, which was taken orally for conditions
ranging from glaucoma to multiple sclerosis. Anthraquinones present in latex are a potent laxative. It increases intestinal water content,
stimulates mucus secretion, and increases intestinal peristalsis. There is no good evidence.
A. vera is of use in treating wounds or burns. There is no good evidence that topical application of A. vera is effective for treating
genital herpes or psoriasis. Topical application of A. vera is provided to treat or prevent phlebitis caused by intravenous infusion.
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12. ADVANTAGES AND DISAVANTAGES OF ALOEVERA
Advantages :
 Aloe vera is high in vitamins
 Aloe vera is high in Amino Acid & Fatty acid
 Aloe vera helps digestion.
 Aloe vera helps in detoxification.
 Aloe alkalizes the Body.
 Aloe vera is : Disinfectant , Antimicrobial, Antiseptic , Antifungal.
 Fight bacterial, viral and fungal infection.
 Increases the body’s alkalinity.
 Supports the cardiovascular system.
 Improve metabolism and weight loss.
Disadvantages :
 Aloe vera juice contain Anthraquinone which causes
 allergic reaction like skin rash.
 Difficulties in Berating.
 Aloe vera contain latex causes
 stomach pain and ulcer.
 High use of aloe causes
 lowers the blood sugar.
 Prolong use of aloe vera juice can
 increase the risk of Constipation.

13.  CONCLUSION:
 Aloe vera is a small farm field plant that has a wide spectrum of the properties and uses. It contains multiple
pharmacologically active substances with diverse biological activity. As literature reveals, plant is of immense therapeutic
value as it is used to cure constipation, skin burns, wounds, psoriasis, dermatitis, potential worsening, pressure ulcers,
mucositis, acne, lichen planus, frostbite, and aphthous stomatitis. Plant contains anticancer, antioxidant, anti-
inflammatory, antiparasitic, and antimicrobial activities. Its sap is used to treat glaucoma to multiple sclerosis. In
Ayurveda, so many therapeutic preparations are based on Aloe vera. The plant is used widely in the traditional herbal
medicine of many countries. Plant is a good choice of cosmetic and pharmaceutical industries as they are using it for
preparation of pain soothing, moisturizing, face shining creams, makeup products, tissues, moisturizers, soaps, sunscreens,
incense, shaving cream, or shampoos. Aloe juice and gel provide protection for humans from sunburn. Aloe vera gel is
used commercially as an ingredient in yogurts and beverages in tropical countries. Anthraquinones present in latex are a
potent laxative.
 It increases intestinal water content, stimulates mucus secretion, and increases intestinal peristalsis. Plant also shows
allergic reactions which are mostly due to presence of anthraquinones, such as aloin and barbaloin. Prolonged use or
overuse of plant juice increases the risk of colorectal cancer. Plant juice is used as a fresh food preservative while plant
canopy assists in water conservation in small farms. Aloin found in the exudate is a laxative natural product. A. vera
shows potential toxicity, with side effects occurring at higher dose levels both when ingested and applied topically. Before
adding A. vera sap to prepare fairness creams, aloin is removed by processing. A. vera juice is marketed to support the
health of the digestive system.

14. A.vera is a good nutrition supplementation for diabetic wound healing. Its gel showed bacteriostatic and/or bactericidal effects on culture.
A. vera is capable of modulating cellular phenotypes and functions. Stabilized diluted A. vera gel is used to make good supplement drink to beat
dehydration. Because Aloe species found in various climates and possess various biologically active compounds which are of very high therapeutic value.
Among them, some are cultivable and domestic, but more than 57 species of it are grown in wild which are of immense ethno pharmacological importance,
they are facing stress of extinction. Hence, they need immediate concern of conservation and preservation of their germ plasm to carry forward genetically
important plant diversity which is chemo typically too important to save the future of ethnic groups.
REFERENCE:
Baby J, Justin SR. pharmacogenetic and phytochemical properties of aloe vera.
International journal of pharmaceutical science review and research 2010
Benefits of aloe vera plant, aloe vera juice aloe vera product
From www.knowledgepublisher.com
Dr.Indu Mehta, 2017 journal of Humanities and Social Science volume 22, Issue 08, Ver 16.
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