Portugal established an early dominance in exploration under Prince Henry the Navigator, with Bartolomeu Diaz and Vasco de Gama expanding Portugal's reach down the African coast and discovering a route to India, making Portugal the most powerful European nation. Christopher Columbus, sponsored by Spain, sought a western route to Asia and instead landed in the Caribbean, conquering the local populations who were later decimated by smallpox, with Columbus ultimately dying in poverty. Spain and Portugal divided control of the new world through the Treaty of Tordesillas, guaranteeing wealth and influence for both nations and the Catholic Church. Hernan Cortes and Francisco Pizarro then conquered the Aztec and Inca empires respectively in South America,