Neural tube defects (NTDs) occur when the neural tube fails to close properly during early embryonic development between the 2nd and 4th week of gestation. The two most common NTDs are spina bifida, where the spine does not fully close, and anencephaly, where parts of the brain and skull are missing. NTDs can be caused by both genetic and environmental factors like folic acid deficiency, though often the cause is unknown. Prenatal screening tests and ultrasounds can detect NTDs, and postnatal care requires a multidisciplinary team to address issues like mobility, bladder/bowel function, and risk of infection. Taking folic acid supplements before and during early pregnancy can help prevent