This document summarizes research evaluating uncertainties in comparing ground-measured land surface temperature (LST) to satellite-derived LST. The researchers used high-resolution ASTER imagery to characterize sub-pixel variability within low-resolution satellite pixels containing ground measurement sites. Preliminary analysis of four sites found mean differences between synthetic low-resolution pixels and in situ measurements of around 1K, with standard deviations of about 2K, indicating ground measurements can help validate satellite LST if accurate. However, systematic differences between sensor measurements were a major source of uncertainty. More data analysis is needed to better understand seasonal variability.