A Beginner's Guide to Writing a Research Article , For Post Graduate Trainees and Senior Registrars , defining basic structure of an article or a publication. Describes different components of a publication or a Research
The manuscript writing process for medical writersPaul Giles, PhD
This slide presentation outlines the logical order of steps to be taken when writing a manuscript for a peer-reviewed journal as a medical writer in a communications team, writing on behalf of a client. Reference is made to industry guidelines, requirements and standards.
The manuscript writing process for medical writersPaul Giles, PhD
This slide presentation outlines the logical order of steps to be taken when writing a manuscript for a peer-reviewed journal as a medical writer in a communications team, writing on behalf of a client. Reference is made to industry guidelines, requirements and standards.
Learn about the principles behind the surgical checklist and the evidence for adopting the checklist and how one NHS Board has applied the checklist to their surgical theatres and how another has expanded the checklist principle to other areas.
Clinical practice guidelines are “systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances.”They are intended to offer concise instructions on how to provide healthcare services.The most important benefit of clinical practice guidelines is their potential to improve both the quality or process of care and patient outcomes. Increasingly, clinicians and clinical managers must choose from numerous, sometimes differing, and occasionally contradictory, guidelines.
Medical Writing and the Technical WriterBill Dubie
At the April 2010 meeting of the Society for Technical Communication Northern New England Chapter, medical writer Bill Greuner described his transition from technical writer to medical writer, discussing what technical writers looking into this field should look for and how to prepare.
As a researcher, you are expected to start publishing early in your career. But original research could take years to complete! This does not mean you that you cannot publish a paper until you complete your research. You can disseminate your research in many other ways. These slides will help you learn more about the different types of scholarly literature so that you are able to choose the most suitable format for publishing your study.
Protocol writing in clinical research kamalKamal Perera
Perera P.K. Resource person: Workshop on Protocol Writing in Clinical Research: BMARI, Nawinna, Maharagama,Sri Lanka. Organized by: Bandaranaike Memorial Ayurvedic Research Institute (BMARI) Collaboration with World Health Organization 27th January 2015, at Bandaranaike Memorial Ayurvedic Research Institute, Nawinna, Sri Lanka.
How FDA will reject non compliant electronic submissionKevin Lee
Beginning Dec 18, 2016, all clinical trial and nonclinical trial studies must use standards (e.g., CDISC) for submission data and beginning May 5, 2017, NDA, ANDA, and BLA submissions must follow eCTD format for submission documents.
In order to enforce these standards mandates, the FDA also released "Technical Rejection Criteria for Study Data" in FDA eCTD website on October 3, 2016. FDA also implemented a rejection process for submissions that do not conform to the required study data standards.
The paper will discuss how these new FDA mandates impact the electronic submission and the required preparation for CDISC and eCTD complaint submission package such as SDTM, ADaM, Define.xml, SDTM annotated eCRF, SDRG, ADRG and SAS® programs. The paper will introduce the current FDA submission process, including the current FDA rejection processes – “Technical Rejection” and “Refuse-to-File” and discuss how FDA uses “Technical Rejection” and “Refuse-to-File” to reject submission. The paper will show how FDA rejection of CDISC non-compliant data will impact sponsor’s submission process, and how sponsors should respond to FDA rejections as well as questions throughout the whole submission process. Use cases will demonstrate the key technical rejection criteria that will have the greatest impact on a successful submission process
Declaration of Geneva and International Code of Medical Ethics..pptxSinghPrabh
The Declaration of Geneva is one of the World Medical Association's (WMA) oldest policies adopted by the 2nd General Assembly in Geneva in 1948. It builds on the principles of the Hippocratic Oath and is now known as its modern version.
It is a declaration of a physician's dedication to the humanitarian goals of medicine
The Declaration of Geneva was intended as a revision of the Hippocratic Oath to formulate that oath's moral truths that could be comprehended and acknowledged modernly.
Learn about the principles behind the surgical checklist and the evidence for adopting the checklist and how one NHS Board has applied the checklist to their surgical theatres and how another has expanded the checklist principle to other areas.
Clinical practice guidelines are “systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances.”They are intended to offer concise instructions on how to provide healthcare services.The most important benefit of clinical practice guidelines is their potential to improve both the quality or process of care and patient outcomes. Increasingly, clinicians and clinical managers must choose from numerous, sometimes differing, and occasionally contradictory, guidelines.
Medical Writing and the Technical WriterBill Dubie
At the April 2010 meeting of the Society for Technical Communication Northern New England Chapter, medical writer Bill Greuner described his transition from technical writer to medical writer, discussing what technical writers looking into this field should look for and how to prepare.
As a researcher, you are expected to start publishing early in your career. But original research could take years to complete! This does not mean you that you cannot publish a paper until you complete your research. You can disseminate your research in many other ways. These slides will help you learn more about the different types of scholarly literature so that you are able to choose the most suitable format for publishing your study.
Protocol writing in clinical research kamalKamal Perera
Perera P.K. Resource person: Workshop on Protocol Writing in Clinical Research: BMARI, Nawinna, Maharagama,Sri Lanka. Organized by: Bandaranaike Memorial Ayurvedic Research Institute (BMARI) Collaboration with World Health Organization 27th January 2015, at Bandaranaike Memorial Ayurvedic Research Institute, Nawinna, Sri Lanka.
How FDA will reject non compliant electronic submissionKevin Lee
Beginning Dec 18, 2016, all clinical trial and nonclinical trial studies must use standards (e.g., CDISC) for submission data and beginning May 5, 2017, NDA, ANDA, and BLA submissions must follow eCTD format for submission documents.
In order to enforce these standards mandates, the FDA also released "Technical Rejection Criteria for Study Data" in FDA eCTD website on October 3, 2016. FDA also implemented a rejection process for submissions that do not conform to the required study data standards.
The paper will discuss how these new FDA mandates impact the electronic submission and the required preparation for CDISC and eCTD complaint submission package such as SDTM, ADaM, Define.xml, SDTM annotated eCRF, SDRG, ADRG and SAS® programs. The paper will introduce the current FDA submission process, including the current FDA rejection processes – “Technical Rejection” and “Refuse-to-File” and discuss how FDA uses “Technical Rejection” and “Refuse-to-File” to reject submission. The paper will show how FDA rejection of CDISC non-compliant data will impact sponsor’s submission process, and how sponsors should respond to FDA rejections as well as questions throughout the whole submission process. Use cases will demonstrate the key technical rejection criteria that will have the greatest impact on a successful submission process
Declaration of Geneva and International Code of Medical Ethics..pptxSinghPrabh
The Declaration of Geneva is one of the World Medical Association's (WMA) oldest policies adopted by the 2nd General Assembly in Geneva in 1948. It builds on the principles of the Hippocratic Oath and is now known as its modern version.
It is a declaration of a physician's dedication to the humanitarian goals of medicine
The Declaration of Geneva was intended as a revision of the Hippocratic Oath to formulate that oath's moral truths that could be comprehended and acknowledged modernly.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
2. Objectives of this Presentation
• How to write an Article / Research Paper ??
• Structure of a research article ….
• Terminologies associated with research …..
• How to Cite / How to find References in a research?.....
• Creating a Google Scholar Profile / How to Use Google Scholar ….
• Role of Chatgpt in Research / Plagiarism / Similarity index / Paraphrasing
• Brief look at Case Report structure and Clinical Audit
7. Structure and Sections of a Research Writing (IMRAD )
• Abstract ( Background , Objective , Material and
method , Results , Conclusion )
• Title
• Introduction
• Material and Method
• Results
8. • Discussion
• Conclusions
• Key Words
• Conflict of Interests
• Source of Funding
• Consent
• References / Citable Evidence / Bibliography
9. Consent Form
• I_________________________________________ give my consent for this information about
myself, relating to the subject matter above to appear in a journal article, or to be used for the
purpose of a thesis or presentation.
• I understand the following:
• The Information will be published without my name attached and every attempt will be made
to ensure anonymity. I understand, however, that complete anonymity cannot be guaranteed.
• The Information may be published in a journal which is read worldwide or an online journal.
Journals are aimed mainly at health care professionals but may be seen by many non-doctors,
including journalists.
• The Information may be placed on a website.
• I can withdraw my consent at any time before online publication, but once the Information has
been committed to publication it will not be possible to withdraw the consent.
•
• Signed:__________________________________ Date: ______________________
10. Data Form / Data Sheet
• Create a Data Form with Patient’s Biodata
• As comprehensive as possible
• Manageable
• Include all the factors , you need to study
11. Abstract
• Summary / Quick Look / Attraction point / Quintessential Marketing Tool
• 250 – 300 words
• May be the Only visible part at some places
• Background ( Briefly describe significance of study in 2 sentences or 3)
• Objective ( The purpose of study )
• Material and method ( Main inclusion criteria , study group and intervention or
parameters used )
• Results
• Conclusion
12. Title
• Reflective / Appropriate
• Word Count ( 14 )
• Easily searchable keywords on PubMed or Medline
• Should Get more Citations and Reads
• Should include the main factor or disease studied
• Should include the population studied
• Can include design of Study
13. Introduction
• Should Generate Curiosity to read More
• Significance of Your study
• What are you intending to achieve with it ?
• What’s New in it ?
• Explain the Utility of your work
• Suitably balance between being very obvious and avoid unnecessary details .
• 7 – 10 References
14. Introduction
• Typically Contains 3 Paragraphs
• 1st Indicating : Background of disease , Disease Burden , Prevalence ,
indicating how Significant your work is ….
• 2nd is Literature on the subject : Worldwide , General beliefs …
• 3rd is Local work / Studies in Pakistan on the subject
• Always end with thus there is need to study …. Thus indicating the
purpose of this study …
15. Material and Method
• Mention Type of Study
• Where was the work done
• Period of your research
• Explain in details what Parameters you are using
• Explain your Data Collection Process
16. Material and Method
• Should Include Statistical Analysis of your Variable e.g. Age , with
means and standard Deviation
• Level of significance and software Used
• Justification of sample size
• Take Help from Biostatistician where Stuck
17. Material and Method
• Explain all the Variables upon which you can base your results
• Contains Inclusion and Exclusion Criteria ***
• Do not contains References / Citable Evidence
• Mention of Gadgets and Tools ( Biochemical , Radiological , Clinical )
• Mention briefly that consent was obtained from Ethical committee
18. Standard Deviation
• Mean ( Add all values / Number )
• Difference from Mean ( Each Value , + , - )
• Square of each Difference
• Add them ( The squared Values )
• Divide this value by n- 1 ( n is number of values )
…. Variance
• Square root the Variance is your SD
• Indicates Errors and Skewed Values
19. Results
• Do not contains References
• Do not contains Commentary or Discussion
• Simply mention values and your results
• No need to repeat material and method
• Do not use the phrases as … surprisingly , interestingly etc.
• Can use both text / tables and figures …. / Pie charts / Data Summary
• Data if numerical will be with Standard Deviations
20. Discussion
• Starts with brief recap of main finding of your study
• But in Recap do not repeat your results , just rephrase in a way that shows the core
of your results / trend
• Compare your results with similar credible studies conducted worldwide ( With
References )
• Should include 7- 10 References
• Do criticize the other studies , to elevate your study but be diplomatic
21. Discussion
• Force your reader to believe this is not “ Just another Paper’’ but a significant
progress in literature
• Mention Your Shortcomings / Criticize your on work with promise to rectify in
future research work
• Again Typically Contains 3 paragraphs
• 1st …. Rephrasing of results
• 2nd …. Worldwide Comparison with similar Study
• 3rd …. Comparison or mention of local work in the same domain + Self analysis
and mention of shortcomings with promise to future work …..
25. References
• Can be up to 20
• Widely accepted facts , need not to be referenced
• Equally distributed in Introduction and Discussion
• Source : PubMed / Medline / Google Scholar
• Use Open access / Public articles on PubMed to avoid future Trouble
or Copyright issues
26. References
• DOI ( Digital Object Identifier ) ….. CrossRef.org ( Using Metasearch )
• URL
• Apart from articles … published books and tables from books can also
be referenced , but should be properly cited
• Follow Your journal guidelines for styling of references
27. References
• Can be written as Superscript BPH 2 , Superscript with Brackets (9) , Plain Brackets
[ 9 ]
• MLA ( Modern Language Association ) system Humanities and Arts
• APA (American Psychological Association ) Education and Psychology
• Harvard system
• Vancouver Style ( Medicine and Health Sciences ) / NLM ( National Library of
Medicine ) / Author-Number System / AMA ( American Medical Association )
• MHRA ( Modern Humanities Research Association ) System
28. Example of Vancouver Styling
Format x. Author(s). Title. Edition. Place of
publication: Publisher; Year.
Example
1. Wilkinson IB, Raine T, Wiles K,
Goodhart A, Hall C, O'Neill H. Oxford
handbook of clinical medicine. 10th ed.
Oxford: Oxford University Press; 2017.
30. Reference Converter / Reference Launcher
• Site this for me
• MyBib
• Citation Machine
• Journal Sites
31.
32. Conflict of Interest / Source of Funding
• A conflict of interest is anything that interferes with,
or could reasonably be perceived as interfering with,
the full and objective presentation, commissioning,
peer review, editorial decision-making, or publication
of research or non-research articles submitted to AIP
Publishing Journals.
33. EXAMPLES of Conflict of Interest
•Comparison of Efficacy And Safety Between
Tamsulosin And Ureterorenoscopy For 1.5
cm Mid Ureteric STONE
34. •Source of Funding : CCL Pharma /
Get Pharma /….
•Might be getting a grant or payment
35. Example of Conflict of Interest
• Research Articles on COVID Vaccines ….sponsored by
Pfizer
• Most Famous example in year 2020 : Relation of
vitamin D levels with morbidity and mortality related
to Coronavirus
36. Example
• Relationship /employee of the editorial Board / Work of same
organization
• It’s a Reader’s Right to Know the statement for conflict of
interest and Source of Funding
37. Key words / MeSH (Medical Subject
Headings)
• Use Commonly used PubMed friendly Key words to get for Citations
and Reads….
• Easily Discoverable …..
38. Adjuvants
• Title Page ( Name and Titles of Authors , Word count, Number of Figures and
Tables )
• Declaration Form ( Undertaking with name of Authors and Signatures )
• Covering Letter ( Letter to editor stating significance of research and request for
Publication)
• Check - List