Here are the key points about chemical-induced toxicity:
- Chemical toxicity to organs and tissues, especially the liver, is a major global health issue.
- The liver plays a key role in metabolizing, detoxifying and eliminating toxins from the body.
- Exposure to toxins from agricultural, industrial and pharmaceutical chemicals as well as food additives and contaminants can cause liver injury.
- Oxidative stress and mitochondrial dysfunction are important mechanisms of chemical-induced liver toxicity.
- Certain chemicals are specifically hepatotoxic (toxic to the liver) while others may cause multi-organ toxicity.
- Understanding the mechanisms of chemical toxicity can help develop preventive and therapeutic strategies to reduce toxicity.