Which intermolecular porcess primarly drives the formation of a bilayer when phospholipids are added to water? Which intermolecular porcess primarly drives the formation of a bilayer when phospholipids are added to water? A-Lipids cause water to arrange in an ordered, unfavorable cage-like structure. B-Forcing lipids into a bilayer reduces this effect. C-The ordered arrangement of a bilayer is more favorable than the disordered state of individual free-floating phospholipids. D-A bilayer arrangement maximizes the strength of hydrophobic interactions among phospholipids. E-Phospholipids self-assemble inot a bilayer due to the strong affinity they have for each other. Solution Thanks for your query. As the lipid bilayer forms the surface of the cell. there is an important point that we have to understand here., That is the lipid cell is hydrophilic on one end and hydrophobic on the other end. Therefore, the hydrophobic ends of both cells join in the center of the lipid bilayer and the hydrophilic ends expose themselves to the outer surface and the inner surface. Since they are hydrophilic they can easily interact with the fluids they are exposed to unlike the hydrophobic ends. Therefore the correct option is D Thanks.