Anaplastic lymphoma kinase also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is an enzyme that in humans is encoded by the ALK gene. ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. Transduces signals from ligands at the cell surface, through specific activation of the mitogen-activated protein kinase (MAPK) pathway.The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Anti-ALK - http://www.stjohnslabs.com/alk-antibody-p-91127?filter_name=STJ91562 Join our Antibody Validation Project - http://www.stjohnslabs.com/services/antibody-validation