This chimeric antibody binds to CD25 expressed in CHO cells. It has been evaluated in a phase I/II clinical study for human renal transplantation with promising results. The antibody is chimeric human/mouse IgG that was tested to bind specifically to native human CD25. It has been reported for use in functional and blocking assays, though the optimal conditions need to be determined for specific assays.

1. cd25 antibody
• Recombinant Chimeric (Human/Mouse) Antibody (CHI621) is capable
of binding to CD25, expressed in Chinese Hamster Ovary cells (CHO).
This chimeric antibody (SDZ CHI621) has been evaluated in a phase
I/II clinical study in human renal cadaver transplantation and has
shown very promising results.

2. • Specifications
• ImmunogenHuman interleukin 2 receptor subunit alpha
• HostChimeric (Human/Mouse)
• DerivationChimeric (Human/Mouse)
• TypeIgG
• SpecificityTested positive against native CD25
• Species ReactivityHuman
• CloneCHI621
• ApplicationsFuncS Assay-Dependent
• Block Assay-Dependent
• Applications
• Application NotesThe antibody CHI621 has been reported in applications of FuncS, Block. It's recommended that the optimal antibody
concentration, dilution, incubition time etc. are best to be carefully titrated in specific assays.

3. • Target
• Alternative NamesP55; CD25; IL2R; IMD41; TCGFR; IDDM10
• Entrez Gene ID3559
• UniProt IDP01589

4. • For lab research use only, not for diagnostic, therapeutic or any in
vivo human use.