Viruses are non-cellular, obligate intracellular parasites that consist of nucleic acid (DNA or RNA) surrounded by a protein coat. They can only replicate inside living host cells by using the host's cellular machinery. Viruses come in a variety of shapes and sizes but are generally quite small, ranging from 18-400 nm. They are classified based on their nucleic acid composition and structure. Viruses infect both plants and animals and include important human pathogens.