This document discusses how Real-Time Location Systems (RTLS) can help overcome business challenges in hospitals. It provides details on how UCSD Medical Center implemented an RTLS solution to track assets across its various facilities. The system uses tags and sensors to track over 2,500 assets in real-time. This has increased staff productivity, reduced equipment rental fees by over $60,000 annually, eliminated budget redundancies saving $450,000, and helped efficiently recall medical devices. The RTLS was also critical during a disaster to prepare and track equipment across overloaded hospitals. In summary, RTLS provides significant benefits in healthcare including improved equipment utilization, reduced costs, automated processes, better staff efficiency, and enhanced patient safety.