Universal precautions were introduced in the 1980s during the AIDS epidemic to prevent transmission of diseases in healthcare settings. They involve treating all human blood and bodily fluids as if known to be infectious. Key elements include hand hygiene, use of personal protective equipment like gloves and masks, safe handling of sharps, and disinfection. Universal precautions are important for surgical practice due to risk of bloodborne pathogens like HIV, hepatitis B, and hepatitis C. Proper use of protective barriers and treatment after exposure can help prevent disease transmission to both patients and healthcare workers.