The document discusses the relationship between hepatitis C virus (HCV) infection and diabetes mellitus (DM). It notes that the liver plays an important role in glucose metabolism, which helps explain the association between cirrhosis and impaired glucose regulation. There is increasing evidence that HCV infection is linked to DM by mechanisms like pancreatic beta cell damage. DM can accelerate liver disease progression in HCV patients. Traditional antiviral therapy has been shown to improve DM outcomes and reduce risks of complications like heart attack and stroke. However, the impact of new direct-acting antiviral treatments on DM needs further research. Overall control of DM is important for good response to HCV treatment and reducing related complications.