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Types of
Skeletal
Muscle
Fibers
Andrea Audine Padernal Jandongan
Ma. Windee Nonesco Ireneo
 Skeletal muscle fibers are not all alike in
composition and function. For example, muscle
fibers vary in their content of myoglobin.
Myoglobin - the red-colored protein
that binds oxygen in musclefibers.
 Skeletal muscle fibers that have a high
myoglobin content are termed red muscle fibers
and appear darker (the dark meat in chicken legs
and thighs); those that have a low content of
myoglobin are called white muscle fibers and
appear lighter (the white meat in chicken breasts).
Red muscle fibers
also contain more mitochondria and are
supplied by more blood capillaries.
 Skeletal muscle fibers also contract and relax
at different speeds, and vary in which metabolic
reactions they use to generate ATP and in how
quickly they fatigue. For example, a fiber is
categorized as either slow or fast depending on
how rapidly the ATPase in its myosin heads
hydrolyzes ATP.
 Based on all these structural and
functional characteristics, skeletal muscle
fibers are classified into three main types:
(1) slow oxidative fibers (SO), (2) fast
oxidative–glycolytic fibers (FOG), and (3)
fast glycolytic fibers (FG).
Slow Oxidative Fibers
(Type I Fibers) (Slow-Twitch
Fibers)
 Slow oxidative (SO) fibers appear dark red
because they contain large amounts of myoglobin
and many blood capillaries. Because they have
many large mitochondria, SO fibers generate ATP
mainly by aerobic respiration, which is why they
are called oxidative fibers.
Aerobic Respiration is the process of
producing cellular energy involving
oxygen. Cells break down food in the
mitochondria in a long, multi-step
process that produces ATP.
 These fibers are said to be “slow” because the
ATPase in the myosin heads hydrolyzes ATP
relatively slowly and the contraction cycle proceeds
at a slower pace than in “fast” fibers. As a result, SO
fibers have a slow speed of contraction. Their twitch
contractions last from 100 to 200 msec, and they
take longer to reach peak tension.
 However, slow fibers are very resistant to
fatigue and are capable of prolonged, sustained
contractions for many hours. These slow-twitch,
fatigue-resistant fibers are adapted for maintaining
posture and for aerobic, endurance-type activities
such as running a marathon.
Fast Oxidative - Glycolytic Fibers
(Type IIa Fibers)
 Fast oxidative - glycolytic (FOG) fibers are
typically the largest fibers. Like slow oxidative fibers,
they contain large amounts of myoglobin and many
blood capillaries. Thus, they also have a dark red
appearance. FOG fibers can generate considerable
ATP by aerobic respiration, which gives them a
moderately high resistance to fatigue.
 Because their intracellular glycogen level is high,
they also generate ATP by anaerobic glycolysis.
FOG fibers are “fast” because the ATPase in their
myosin heads hydrolyzes ATP three to five times
faster than the myosin ATPase in SO fibers, which
makes their speed of contraction faster.
 Thus, twitches of FOG fibers reach
peak tension more quickly than those of
SO fibers but are briefer in duration-less
than 100 msec. FOG fibers contribute to
activities such as walking and sprinting.
Sprinter vs. Marathoner
Types of Skeletal Muscle Fibers
Types of Skeletal Muscle Fibers

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Types of Skeletal Muscle Fibers

  • 1. Types of Skeletal Muscle Fibers Andrea Audine Padernal Jandongan Ma. Windee Nonesco Ireneo
  • 2.  Skeletal muscle fibers are not all alike in composition and function. For example, muscle fibers vary in their content of myoglobin. Myoglobin - the red-colored protein that binds oxygen in musclefibers.
  • 3.  Skeletal muscle fibers that have a high myoglobin content are termed red muscle fibers and appear darker (the dark meat in chicken legs and thighs); those that have a low content of myoglobin are called white muscle fibers and appear lighter (the white meat in chicken breasts).
  • 4. Red muscle fibers also contain more mitochondria and are supplied by more blood capillaries.
  • 5.  Skeletal muscle fibers also contract and relax at different speeds, and vary in which metabolic reactions they use to generate ATP and in how quickly they fatigue. For example, a fiber is categorized as either slow or fast depending on how rapidly the ATPase in its myosin heads hydrolyzes ATP.
  • 6.  Based on all these structural and functional characteristics, skeletal muscle fibers are classified into three main types: (1) slow oxidative fibers (SO), (2) fast oxidative–glycolytic fibers (FOG), and (3) fast glycolytic fibers (FG).
  • 7.
  • 8. Slow Oxidative Fibers (Type I Fibers) (Slow-Twitch Fibers)  Slow oxidative (SO) fibers appear dark red because they contain large amounts of myoglobin and many blood capillaries. Because they have many large mitochondria, SO fibers generate ATP mainly by aerobic respiration, which is why they are called oxidative fibers.
  • 9. Aerobic Respiration is the process of producing cellular energy involving oxygen. Cells break down food in the mitochondria in a long, multi-step process that produces ATP.
  • 10.  These fibers are said to be “slow” because the ATPase in the myosin heads hydrolyzes ATP relatively slowly and the contraction cycle proceeds at a slower pace than in “fast” fibers. As a result, SO fibers have a slow speed of contraction. Their twitch contractions last from 100 to 200 msec, and they take longer to reach peak tension.
  • 11.  However, slow fibers are very resistant to fatigue and are capable of prolonged, sustained contractions for many hours. These slow-twitch, fatigue-resistant fibers are adapted for maintaining posture and for aerobic, endurance-type activities such as running a marathon.
  • 12.
  • 13. Fast Oxidative - Glycolytic Fibers (Type IIa Fibers)  Fast oxidative - glycolytic (FOG) fibers are typically the largest fibers. Like slow oxidative fibers, they contain large amounts of myoglobin and many blood capillaries. Thus, they also have a dark red appearance. FOG fibers can generate considerable ATP by aerobic respiration, which gives them a moderately high resistance to fatigue.
  • 14.  Because their intracellular glycogen level is high, they also generate ATP by anaerobic glycolysis. FOG fibers are “fast” because the ATPase in their myosin heads hydrolyzes ATP three to five times faster than the myosin ATPase in SO fibers, which makes their speed of contraction faster.
  • 15.  Thus, twitches of FOG fibers reach peak tension more quickly than those of SO fibers but are briefer in duration-less than 100 msec. FOG fibers contribute to activities such as walking and sprinting.
  • 16.