Trypanosoma is an extracellular blood parasite with a corkscrew-like motion due to its flagellum. It has a complex life cycle involving mammalian hosts and insect vectors. The life cycle begins when an infected tsetse fly or reduviid bug takes a blood meal and transmits the trypomastigote form to mammals. Inside mammals, the parasites multiply and spread through the bloodstream as trypomastigotes before differentiating into epimastigotes inside the insect vector, completing the life cycle.