The NIH remains committed to training the next generation of biomedical scientists reflecting the scientific needs of the funded research. The NIH agrees that the training of quantitative scientists is critical to continuing the advancement of biomedical science, especially in the era of big data and complex genomic data. We will describe efforts in this direction through the Big Data to Knowledge BD2K Initiative. Presented at the AAAS Meeting, San Jose, CA, February 16, 2015.