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TOXICITY FROM FOOD OF
ANIMAL ORIGIN
Ms.Rabia Shabbir
Nutritional Psychologist
CONTENTS
 Toxic intrinsic factors in animal origin food
 Toxicity from
 Honey
 Quail
 Raw eggs
 Milk
 Poultry
 Beef and mutton
 Fish
2
NATURAL TOXINS IN FOODS
FROM ANIMAL ORIGIN
1. BACTERIAL TOXINS
2. EDIBLE ALGAE TOXINS
3. MYCOTOXINS
3
BACTERIAL TOXINS
4
EDIBLE ALGAE TOXINS
 The most common toxicity from edible algae is
heavy metals toxicity.
 As microalgae are capable of accumulating heavy
metal ions by biosorption, traces of heavy metals
may be found in algal food products.
5
FACTSABOUTHEAVYMETALCONSUMPTION
According to WHO/FAO guidelines,
an adult person of 60 kg body weight
should not incorporate more than
 0.3mg of mercury
 0.5 mg of cadmium
 3 mg of lead
 20 mg of arsenic per week
from beverages and foods
6
MYCOTOXINS
 Milk and dairy products, poultry, eggs, tissues of
animal origin food can contain aflatoxins, whose
toxicity was first reported in 1960s by consumption
of milk.
7
TOXICITY
FROM
HONEY
8
 Honey bees can gather toxic chemicals while feeding on some
toxic plants
 Such substances may not have adverse effects on the bees
consuming them
 Honey produced from the nectar of Rhododendron ponticum
(also called as Azalae pontica) contains alkaloids that are
poisonous to humans.
 Honey from the nectar of Andromeda flowers contain
grayanotoxins that are notorious in causing “mad honey
disease” or “grayanotoxins poisoning”
 Mad honey disease is characterized by bradycardia,
cardiac arrhythmias, hypotension, nausea, vomiting,
dizziness, convulsions.
9
 Bee nectar from Datura plants, belladona flowers and
oleander also cause honey toxicity.
 Toxicity can also result when inexperienced workers gather
honey from wild bees and sale it.
 A compound not naturally present in honey, named 5-
hydroxymethylfurfural (HMF), may be formed during the
heating or preservation processes of honey.
 HMF is a compound that may be mutagenic, carcinogenic and
cytotoxic
10
TOXICITY
FROM
QUAIL
11
 Scientifically known as Coturnix coturnix
 Toxicity- COTURNISM
 It includes muscle tenderness even muscle breakdown, limb
paralysis, nausea and vomiting, discoloration of urine, cardiac
and kidney failure, even death.
 Quail is a migratory bird and can accumulate poisonous
plants like Hamlock and Halloborus.
 Such plants have connine alkaloids that is fatal at level of
100mg in humans.
12
13
 AVIDIN- a protein present in raw egg white, that forms a
stable complex with biotic in human GIT, making it
biologically inactive.
 Also impairs the mechanism of B-complex vitamins
 20 raw eggs/week for several days can produce biotin
avitaminosis which causes fatigue, depression, nausea,
dermatitis, muscular pains.
 Avidin is destroyed on heating. So, fried/boiled eggs doesn’t
cause such toxicity
 Another protein called “CONALBUMIN” is also present in
raw egg white which isolates metallic contaminants such as
iron and copper in egg white
 Salmonella bacterium can also be present on shells of raw
eggs whose consumption can cause abdominal cramps,
diarrhea, nausea, headache.
14
TOXICITY FROM
MILK
15
 Cows feeding on kale and other cruciferous plants secrete
goitrogens in milk.
 Aflatoxin is one of the mycotoxin that have been reported as
carcinogenic-found in dairy products, especially when cow
feeds on moulds.
 Pesticides spray can also cause milk toxicity when a cow
feeds on such ration.
 Similarly, when a vet prescribes antibiotics to animal for
treating any ailment, that can also produce adverse effects on
consumers.
 Estrogens., the female sex hormones, have also been
reported in milk of cow in advancing days of pregnancy. a
pregnant cow contains 33x more estrogens than a non-
pregnant cow.
16
 Bovine somatotropin (BST), is bovine growth hormone in
cattle. Sometimes, BGH injections are given to cow to increase
its milk production. It can cause Mastitis (inflammation of
breast tissues) of cow.
 For treatment of mastitis, cows are given lots of antibiotics
that cause serious adverse effects on consumers including
breast cancer, colon cancer, hormonal imbalance and prostate
problems in humans.
 BGH injection induces the release of Insulin growth factor-1
(IGF-1) in milk that is resistant to pasteurization temperature
and also, to GIT enzymes of humans, leading to various forms
of cancers.
17
 Oxytoxin injections to the cow and buffaloes can disturb
the levels of cholesterol and proteins in milk (more cholesterol
in early milk ejection stage, more protein in later milk ejection
stage).
18
TOXICITY
FROM
POULTRY
19
 Poultry feed consists of cereals, grains, legumes, salts,
vitamins, drugs etc.
 Poultry rations are usually comprised of poultry waste
including skin, feather, blood, bones, egg shells, intestine,
hatchery wastes.
 Antibiotics such as erythromycin, gentamycin, oxytetracycline
are excessively used for poultry treatment.
 Such consumption causes destruction of healthy gut bacteria
of humans and also cause allergic reactions.
20
TOXICITY
FROM BEEF
& MUTTON
21
 Beef cattle, sheep, goats are grazed in fields.
 Infection of cattle by Taenia saginata, known as beef
tapeworm occurs by grazing in fields.
 it can cause diarrhea, nausea, vomiting, anemia, lethargy and
loss of appetite among consumers.
 MAD COW DISEASE (bovine spongiform encephalopathy
BSE) is caused when cattle are fed by inappropriate meats and
bones from scrap. It is most common in Britain.
 TRANSPORTATION COMTAMINATION through hand cart,
bicycle, donkey cart, tonga, rickshaw in Pakistan is quite
common.
 In shops, meat is kept open where it acquires various
environmental contaminants.
 Meat must be kept in refrigeration and be transported
through same.
22
TOXICITY FROM FISH
23
 Most common source of toxicity in humans
 Fish poisoning (tetrodotoxism) occurs mostly in China &
Japan where puffer fishes are consumed.
 This poison is mainly found in liver, intestine, ovaries and
skin of puffer fish.
 s/s include tingling sensation of lips, tongue and cheeks.
Later, it can be complicated with weakness, muscle paralysis,
hypotension, tachycardia, respiratory failure and death.
 Some species of shell fish produce an intrinsic poison.
 Consumption of Red Whelk produces tetramine that cause
nausea, vomiting, anorexia, weakness, dizziness, photophobia,
mouth dryness.
24
 Industrial wastes, oil spills from consignments also cause
damage to sea life and the consumers as well.
 Methylmercury, gasoline, coal, lead are included among such
wastes.
25
26

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toxicity from animal origin foods

  • 1. TOXICITY FROM FOOD OF ANIMAL ORIGIN Ms.Rabia Shabbir Nutritional Psychologist
  • 2. CONTENTS  Toxic intrinsic factors in animal origin food  Toxicity from  Honey  Quail  Raw eggs  Milk  Poultry  Beef and mutton  Fish 2
  • 3. NATURAL TOXINS IN FOODS FROM ANIMAL ORIGIN 1. BACTERIAL TOXINS 2. EDIBLE ALGAE TOXINS 3. MYCOTOXINS 3
  • 5. EDIBLE ALGAE TOXINS  The most common toxicity from edible algae is heavy metals toxicity.  As microalgae are capable of accumulating heavy metal ions by biosorption, traces of heavy metals may be found in algal food products. 5
  • 6. FACTSABOUTHEAVYMETALCONSUMPTION According to WHO/FAO guidelines, an adult person of 60 kg body weight should not incorporate more than  0.3mg of mercury  0.5 mg of cadmium  3 mg of lead  20 mg of arsenic per week from beverages and foods 6
  • 7. MYCOTOXINS  Milk and dairy products, poultry, eggs, tissues of animal origin food can contain aflatoxins, whose toxicity was first reported in 1960s by consumption of milk. 7
  • 9.  Honey bees can gather toxic chemicals while feeding on some toxic plants  Such substances may not have adverse effects on the bees consuming them  Honey produced from the nectar of Rhododendron ponticum (also called as Azalae pontica) contains alkaloids that are poisonous to humans.  Honey from the nectar of Andromeda flowers contain grayanotoxins that are notorious in causing “mad honey disease” or “grayanotoxins poisoning”  Mad honey disease is characterized by bradycardia, cardiac arrhythmias, hypotension, nausea, vomiting, dizziness, convulsions. 9
  • 10.  Bee nectar from Datura plants, belladona flowers and oleander also cause honey toxicity.  Toxicity can also result when inexperienced workers gather honey from wild bees and sale it.  A compound not naturally present in honey, named 5- hydroxymethylfurfural (HMF), may be formed during the heating or preservation processes of honey.  HMF is a compound that may be mutagenic, carcinogenic and cytotoxic 10
  • 12.  Scientifically known as Coturnix coturnix  Toxicity- COTURNISM  It includes muscle tenderness even muscle breakdown, limb paralysis, nausea and vomiting, discoloration of urine, cardiac and kidney failure, even death.  Quail is a migratory bird and can accumulate poisonous plants like Hamlock and Halloborus.  Such plants have connine alkaloids that is fatal at level of 100mg in humans. 12
  • 13. 13
  • 14.  AVIDIN- a protein present in raw egg white, that forms a stable complex with biotic in human GIT, making it biologically inactive.  Also impairs the mechanism of B-complex vitamins  20 raw eggs/week for several days can produce biotin avitaminosis which causes fatigue, depression, nausea, dermatitis, muscular pains.  Avidin is destroyed on heating. So, fried/boiled eggs doesn’t cause such toxicity  Another protein called “CONALBUMIN” is also present in raw egg white which isolates metallic contaminants such as iron and copper in egg white  Salmonella bacterium can also be present on shells of raw eggs whose consumption can cause abdominal cramps, diarrhea, nausea, headache. 14
  • 16.  Cows feeding on kale and other cruciferous plants secrete goitrogens in milk.  Aflatoxin is one of the mycotoxin that have been reported as carcinogenic-found in dairy products, especially when cow feeds on moulds.  Pesticides spray can also cause milk toxicity when a cow feeds on such ration.  Similarly, when a vet prescribes antibiotics to animal for treating any ailment, that can also produce adverse effects on consumers.  Estrogens., the female sex hormones, have also been reported in milk of cow in advancing days of pregnancy. a pregnant cow contains 33x more estrogens than a non- pregnant cow. 16
  • 17.  Bovine somatotropin (BST), is bovine growth hormone in cattle. Sometimes, BGH injections are given to cow to increase its milk production. It can cause Mastitis (inflammation of breast tissues) of cow.  For treatment of mastitis, cows are given lots of antibiotics that cause serious adverse effects on consumers including breast cancer, colon cancer, hormonal imbalance and prostate problems in humans.  BGH injection induces the release of Insulin growth factor-1 (IGF-1) in milk that is resistant to pasteurization temperature and also, to GIT enzymes of humans, leading to various forms of cancers. 17
  • 18.  Oxytoxin injections to the cow and buffaloes can disturb the levels of cholesterol and proteins in milk (more cholesterol in early milk ejection stage, more protein in later milk ejection stage). 18
  • 20.  Poultry feed consists of cereals, grains, legumes, salts, vitamins, drugs etc.  Poultry rations are usually comprised of poultry waste including skin, feather, blood, bones, egg shells, intestine, hatchery wastes.  Antibiotics such as erythromycin, gentamycin, oxytetracycline are excessively used for poultry treatment.  Such consumption causes destruction of healthy gut bacteria of humans and also cause allergic reactions. 20
  • 22.  Beef cattle, sheep, goats are grazed in fields.  Infection of cattle by Taenia saginata, known as beef tapeworm occurs by grazing in fields.  it can cause diarrhea, nausea, vomiting, anemia, lethargy and loss of appetite among consumers.  MAD COW DISEASE (bovine spongiform encephalopathy BSE) is caused when cattle are fed by inappropriate meats and bones from scrap. It is most common in Britain.  TRANSPORTATION COMTAMINATION through hand cart, bicycle, donkey cart, tonga, rickshaw in Pakistan is quite common.  In shops, meat is kept open where it acquires various environmental contaminants.  Meat must be kept in refrigeration and be transported through same. 22
  • 24.  Most common source of toxicity in humans  Fish poisoning (tetrodotoxism) occurs mostly in China & Japan where puffer fishes are consumed.  This poison is mainly found in liver, intestine, ovaries and skin of puffer fish.  s/s include tingling sensation of lips, tongue and cheeks. Later, it can be complicated with weakness, muscle paralysis, hypotension, tachycardia, respiratory failure and death.  Some species of shell fish produce an intrinsic poison.  Consumption of Red Whelk produces tetramine that cause nausea, vomiting, anorexia, weakness, dizziness, photophobia, mouth dryness. 24
  • 25.  Industrial wastes, oil spills from consignments also cause damage to sea life and the consumers as well.  Methylmercury, gasoline, coal, lead are included among such wastes. 25
  • 26. 26