This document discusses the harmful effects of tobacco use, including smoking and smokeless tobacco. Some key points:
- Tobacco use causes over 4 million deaths globally each year, including 8-9 lakh deaths in India. Tobacco-related diseases cost the Indian economy over 27700 crore annually.
- Tobacco contains over 4000 chemicals, including 28 carcinogens. Smokeless tobacco products like gutkha also contain harmful chemicals like nicotine.
- Tobacco use, both smoking and smokeless forms, increases the risk of various cancers like oral, lung, throat and more. It can also cause heart disease, lung disease, reproductive issues and more.
- The Tobacco Act of 2003 in India prohibits tobacco advertising
Health complications of various forms of tobacco such as Chewing tobacco, Snuff, Creamy snuff, Dipping tobacco, Gutka, Snus, Cigarette, Cigar, Bidi, Kretek and Hookah are discussed in this presentation.
Health complications of various forms of tobacco such as Chewing tobacco, Snuff, Creamy snuff, Dipping tobacco, Gutka, Snus, Cigarette, Cigar, Bidi, Kretek and Hookah are discussed in this presentation.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
5. Tobacco Toll
4 million death
globally
8-9 lakh deaths in
India
2200 die of tobacco
use every day in India
Social cost of tobacco
related diseases is
27700 crore
Tobacco the Killer
6. Type of tobacco
Smoking: 15%-20%
of the tobacco
consumed in the form
cigarette
55% in the form
beedis
Smokeless tobacco:
25%-30% in the form
of chewing, snuff etc
Tobacco the Killer
7. Panmasala
1000 gutkha and panmala manufacturing
units
Panmasala entered in Kerala on 1993
35000 kilogram is using every month in
Kerala
Smokeless tobacco consists of dried
leaves and stems of the plant Nicotinia
Tobaccum
8. Contents of smokeless tobacco
28 Carcinogens
Nicotine
Formaldehyde
Acetaldehyde
Crotonaldehyde
Hydrazine
Arsenic
Nickel
Cadmium
Benzopyrene
Polonium
Microscopic abrasives
Cancer to lungs &
respiratory system
Bladder and breast cancer
Nasal cancer
Leukemia
Liver and brain cancer
9. Smokeless tobacco causes cancer
8 lakh new cancer
cases in India every
year
50% of cancer among
men & 20% among
female are tobacco
related
Six fold increased risk
of oral cavity cancer
Tobacco the Killer
10. Smokeless tobacco causes cancer
Cancer of Mouth
Throat
Lungs
Larynx
Oesophagus
Urinary bladder
Pancreas
Cervix
Tobacco the Killer
18. Warning signs
A mouth sore that bleeds easily or fails to
heal
A painless lump, thickening or soreness in
the mouth, throat or tongue
Soreness or swelling that persists
A white or red patch in the mouth that
persists
Difficulty in chewing, swallowing or moving
tongue or jaw
19. Preventive measures
Control over glamorous advertisement & marketing of
tobacco products
Protect children from becoming addictive to tobacco
Generating awareness regarding the ill effects of
tobacco use
Declaring public institution as tobacco free
Involvement of health personnel in awareness campaign
Showing prominent warning on tobacco products
Eliminate sponsorship by tobacco campaign of any
public events
Increase in taxes on tobacco products
20. Smoking
Tobacco & its contents
4000 chemicals – causes cancer and
dangerous to health
21.
22. Tobacco & its contents
Nicotine Severely addictive
drug found in tobacco
smoke
Increase heart rate
and blood pressure
Constricts blood
vessels
Reducing blood flow
to many organs
23. Tobacco & its contents
Tar
Carbon monoxide
Tar contains dozens of
chemicals that causes
cancer
Tobacco smoke makes
the heart beat faster
Gas takes the place of
oxygen in the blood
Reducing the ability of
blood to deliver oxygen to
various body tissues
26. Health hazards of tobacco use
Tobacco & Lung Diseases
Chronic Obstructive
Lung Diseases
Bronchial asthma
Respiratory infection
Progressively
disabling diseases
Rarely reversible
Prolonged suffering
Obstruction or
narrowing of the small
airways in the lungs .
27.
28.
29. Health hazards of tobacco use
Heart & Blood vessel diseases
Arthrosclerosis
Heart attack
Stroke
Peripheral vascular
diseases
Smoking damages
the lining of blood
vessels and leads to
fat deposition
Narrowing of leg
arteries leading to
blockage
30. Health hazards of tobacco use
Lung cancer
Lung cancer kills more people than any
other type of cancer
80% of these deaths are caused by
smoking
31.
32. Health hazards of tobacco use
Cancer of mouth and throat
Smoking is a risk factor associated with
the larynx, oral cavity and esophagus
33. Health hazards of tobacco use
Breast cancer
Increased risk of breast cancer associated
with long term passive smoke exposure
34.
35. Health hazards of tobacco use
Reproductive problems
Impotence in men
Abnormal sperm and a lower than average
sperm count
36. Health hazards of tobacco use
Eye problem
Early cataract
Degeneration of the retina
Partial or complete blindness
37.
38. Smoker Vs. Nonsmokers
20 – 25 times risk of lung cancer
2 -3 times risk of having a heart attack
3 times risk of sudden death
30 – 60% more sick days
39.
40. Passive Smoking
Burning end of the cigarette has very high
concentration of dangerous chemicals
Three times more nicotine and tar
50 times more cancer causing substances
Risk of cancer and heart attack for
spouses of smokers
Lung cancer and nasal sinus cancer
41.
42.
43.
44. Passive smoking
Low birth weight babies
Sudden infant death syndrome
Bronchitis, Pneumonia
Middle Ear Infection
Severity of asthma
Reduced rate of lung growth
48. The Cigarettes And Other Tobacco Products (Prohibition of
Advertisement And Regulation Of Trade And Commerce,
Production, Supply And Distribution) Act,2003
Rules to be enforced from May 1, 2004
Prohibition of smoking in public places
Prohibition of advertisement of cigarettes
and other tobacco products
Prohibition of sale to minors
49.
50. Prohibition of advertisement of cigarettes and other
tobacco products (section 4)
Act prohibits all types of direct and indirect
adv. And any promotion of tobacco
products
Protect people from being misled
Prevent fresh users from picking up the
habit
Protect children and adolescent from
being attracted to tobacco products
51.
52. Effective Tobacco Packages
warning (section 8)
All tobacco products will have to bear the
specified health warning
Warn consumers about ill effects and
harmful constituents
Cautioning potential users
53.
54. Ban on sale of tobacco products to minors and
within 100 yards f educational institutions
(section 6)
Sale of tobacco to a person under the age
of eighteen years is a punishable offence
Mandates that such sign be displayed at
all points of sale
55. Ban on smoking in public places
(section 3)
Acts prohibits smoking in public places
Restaurants, auditoriums, hospital
building, airports, railway waiting rooms,
amusement centres, public offices, court
buildings, educational institutions, libraries
and other open places where people
gather
56.
57. All tobacco products will be
regulated (section 11)
Monitor the ingredients and emission of
tobacco products
58. Tobacco control & Human rights
Right to clean air
Right of the children
Non smokers are
forced to inhale
tobacco smoke in
public places
Rights of the born and
unborn children are
violated when they
are exposed to
tobacco smoke