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SORE THROAT AND FEVER
THROAT PAIN +/- FEVER
A 15 years old boy presented with history of sore throat for 3
days along with high grade fever.
1. What specific question you would ask in history to elicit the diagnosis?
2. Give your differential diagnosis.
3
Introduction
• A sore throat is pain or irritation of the throat
that often worsens when you swallow.
• Fever is the temporary increase in the body's
temperature in response to a disease or illness.
• There are many clinical scenarios where sore
throat is associated with fever. E.g. pharyngitis,
tonsilitis, influenza, laryngitis.
TONSILLITIS
 Tonsills are secondary lymphoid organs
 They consist of stratified squamous
epithelium which invaginates to form
tonsillar crypts
 It is partly covered by a fibrous capsule
 It contains antigen presenting cells along
with T and B lymphocyte
 It provides immunity from pathogens in the
ingested food.
PRESENTATIONTITLE 4
4 types on tonsils form the Waldeyer’s Ring:-
 Palatine tonsils
 Pharyngeal tonsils
 Lingual tonsils
 Tubal tonsils
BLOOD SUPPLY
1. Tonsillar branch of facial artery
2. Ascending pharyngeal artery from external
carotid.
3. Ascending palatine, a branch of facial artery.
4. Dorsal linguae branches of lingual artery.
5. Descending palatine branch of maxillary artery
PRESENTATIONTITLE 5
TYPES OF TONSILLITIS
PRESENTATIONTITLE 6
of duration)
 Recurrent tonsillitis (occurs several
 Acute tonsillitis (less than 4 weeks  Acute catarrhal tonsillitis: occurs due to viral
infection.It is a generalized infection of oral
mucosa.
 Acute cryptic tonsillitis: occurs when bacterial
infection gets entrapped in the crypts.
 Acute follicular tonsillitis occurs when
inflammation spreads to the tonsillar follicles with
purulent material. Presents at the opening of
crypts as yellow spots.
 Acute parenchymal tonsillitis: occurs when
bacterial infection spreads to the tonsillar
parenchyma. Tonsil are uniformly enlarged and red.
 Acute membranous tonsillitis :occurs when
exudates from the crypts coalesce to form a
membrane over the surface of the tonsils.
times a year)
 Chronic tonsillitis (more than 12
weeks of duration)
Bacterial Viral Fungal
Hemolytic
Streptococcus
Adenovirus Candida
Albicans
H.Influenza influenza
virus
PRESENTATIONTITLE 8
PATHOPHYSIOLOGY OF ACUTE
TONSILLITIS
9
 Hemolytic streptococcus enter the oral cavity and attaches
to the tonsillar epithelium (stratified sq) especially in the
crypts.
 Next, the pathogen causes inflammatory response of the
host immune system leading to the release of cytokines
which not only attract WBC but also causes symptoms like
fever, cough and headache to appear.
 Pus is produced while Combating these pathogens which
oozes out of the crypts as multiple pus points.
SIGNS & SYMPTOMS OF
TONSILLITIS
Symptoms
Sore throat
Difficulty in swallowing
Fever
Earache



 General symptoms : headache,
Signs
Hyperemia of the pillars, Soft palate and
uvula
Red, swollen tonsils with yellowish spots of
Purulent material or
Whitish membrane on medial surface of
tonsils
bodyache, Malaise
Breath is fetid
 Coated tongue



 Enlarged and tender lymphnodes
PRESENTATIONTITLE 10
Risk Factors Acute Tonsillitis
11
Predisposed factors of tonsillitis:-
 Extremes of age group
 Immunocompromised individuals (diabetics, organ transplant or
chemotherapeutic patients)
 Abnormal tonsils form previous recurrent tonsillitis
 Generalized pharyngitis
 Overcrowding, poor nutrition, inadequate ventilation
 Exposure to cold
COMPLICATIONS
12
 Chronic tonsillitis
 Pharyngeal abscess
 Rheumatic fever
 Endocarditis
 Peritonsillar abscess
 Cervical abscess
 Acute Otitis media
 Sinusitis
PHARYNGITIS
It is the inflammation of the pharynx,
resulting in a sore throat
The symptoms in pharyngitis are
similar to that in tonsillitis including
pain, fever, dysphagia, swollen
lymph nodes in neck, and a
headache or earache
WHY WE INCLUDED WHY WE EXCLUDED
SYMPTOMS such as:
• Sudden onset
• Soreness
• High fever
• NO HISTORY OF:
• Allergy / post nasal
drip
• GERD
• Smoking
No sign of:
• Tonsillopharyngeal
petechiae
(streptococcal)
• Tonsillopharyngeal
exudate
13
Differential diagnosis of sore
throat and fever
1. Tonsillitis
2. Influenza virus
3. Pharyngitis
4. Corona virus
5. Adenoiditis
6. Peritonsillar abscess
7. Trauma/foreign body.
8. Squamous cell carcinoma of tonsil.
Differentiate between viral upper respiratory tract
infection from bacterial pharyngitis / tonsillitis
15
History questions to ask to elicit
such a diagnosis
1. What has been the duration of sore throat and how did it start?
2. Ask whether it is aggravated from anything or relieved by anything or
not?
3. If there is any sputum production along with sore throat or not?
4. Dysphagia?
5. Any associated symptoms or pain?
6. Did the fever start simultaneously or not?
7. If the fever was continuous ore intermittent?
8. History of allergies?
9. History of any previous URTIs?
10. Any smoking habits or not?
MANAGEMENT
History (points)
Examination
Lab Investigations
Management (medical
and surgical)
PRESENTATIONTITLE 15
LAB
INVESTIGATION
Complete Blood Count
To determine whether the
infection acute or chronic
Culture
To identify the causative organism
using throat swab
Rapid Antigen test
Involves a quick throat swab.
Within minutes, the test can show
the presence of group A
streptococcus bacteria
EXAMINATION
 Use a head mounted light to
inspect the patient
 Check for any swellings, scar
marks, discoloration or
discharge
 Gently palpate and look for any
tenderness or swollen lymph
nodes.
17
Management Of Tonsillitis
MEDICAL
 Treatment of tonsillitis depends on the cause
 Provide adequate fluids intake to keep throat moist and prevent
dehydration.
 Saltwater gargle.
 Analgesics (paracetamol) is given according to patient’s age
to relieve fever and local pain.
 Antibiotics in case of bacterial infections
 Most of infections are due to streptococcus species. Penicillin or
Amoxicillin is the drug of choice and patient allergic to penicillin is
treated with Erythromycin or Azithromycin.
 Amoxicillin for 7 to 10 days. Azithromycin 3-5 days
SURGICAL
. Tonsillectomy:-
It is a surgical procedure to remove tonsils.
Indications :
 Tonsil / adenoid hypertrophy with sleep
apnea syndrome
 Hypertrophy causing dysphagia with
associated weight loss
 Excisional biopsy for suspected
malignancy (lymphoma)
 Recurrent tonsillitis
19
Other methods for tonsillectomy.
PRESENTATIONTITLE 23
1. Electrocautery
2. Laser tonsillectomy
3. Intracapsular tonsillectomy
4. Harmonic scalpel
5. Plasma-mediated ablation technique
6. Coblation tonsillectomy
7. Cryosurgical technique
COMPLICATIONS OF TONSILLECTOMY
PRESENTATIONTITLE 24
A. IMMEDIATE
1.Primary haemorrhage
2.Reactionary haemorrhage
3.Injury to tonsillar pillars, uvula,
soft palate, tongue or superior
constrictor muscle due to bad
surgical technique
4. Injury to teeth
5. Aspiration of blood
6. Facial oedema
7. Surgical emphysema
B. DELAYED
1. Secondary haemorrhage.
2. Infection.
3. Lung complications
4. Scarring in soft palate and pillars.
5. Tonsillar remnants.
Prescription for viral URTI
The basic treatment for viral upper respiratory infections is :
Analgesics : acetaminophen, NSAIDs.
Antihistamine : CHLOPHEDIANOL, DEXBROMPHENIRAMINE is a cough
suppressant and antihistamine.
Nasal decongestant sprays: pseudoephedrine, and phenylephrine.
25

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throat pain.pptx

  • 2. THROAT PAIN +/- FEVER A 15 years old boy presented with history of sore throat for 3 days along with high grade fever. 1. What specific question you would ask in history to elicit the diagnosis? 2. Give your differential diagnosis. 3
  • 3. Introduction • A sore throat is pain or irritation of the throat that often worsens when you swallow. • Fever is the temporary increase in the body's temperature in response to a disease or illness. • There are many clinical scenarios where sore throat is associated with fever. E.g. pharyngitis, tonsilitis, influenza, laryngitis.
  • 4. TONSILLITIS  Tonsills are secondary lymphoid organs  They consist of stratified squamous epithelium which invaginates to form tonsillar crypts  It is partly covered by a fibrous capsule  It contains antigen presenting cells along with T and B lymphocyte  It provides immunity from pathogens in the ingested food. PRESENTATIONTITLE 4
  • 5. 4 types on tonsils form the Waldeyer’s Ring:-  Palatine tonsils  Pharyngeal tonsils  Lingual tonsils  Tubal tonsils BLOOD SUPPLY 1. Tonsillar branch of facial artery 2. Ascending pharyngeal artery from external carotid. 3. Ascending palatine, a branch of facial artery. 4. Dorsal linguae branches of lingual artery. 5. Descending palatine branch of maxillary artery PRESENTATIONTITLE 5
  • 6. TYPES OF TONSILLITIS PRESENTATIONTITLE 6 of duration)  Recurrent tonsillitis (occurs several  Acute tonsillitis (less than 4 weeks  Acute catarrhal tonsillitis: occurs due to viral infection.It is a generalized infection of oral mucosa.  Acute cryptic tonsillitis: occurs when bacterial infection gets entrapped in the crypts.  Acute follicular tonsillitis occurs when inflammation spreads to the tonsillar follicles with purulent material. Presents at the opening of crypts as yellow spots.  Acute parenchymal tonsillitis: occurs when bacterial infection spreads to the tonsillar parenchyma. Tonsil are uniformly enlarged and red.  Acute membranous tonsillitis :occurs when exudates from the crypts coalesce to form a membrane over the surface of the tonsils. times a year)  Chronic tonsillitis (more than 12 weeks of duration) Bacterial Viral Fungal Hemolytic Streptococcus Adenovirus Candida Albicans H.Influenza influenza virus
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  • 9. PATHOPHYSIOLOGY OF ACUTE TONSILLITIS 9  Hemolytic streptococcus enter the oral cavity and attaches to the tonsillar epithelium (stratified sq) especially in the crypts.  Next, the pathogen causes inflammatory response of the host immune system leading to the release of cytokines which not only attract WBC but also causes symptoms like fever, cough and headache to appear.  Pus is produced while Combating these pathogens which oozes out of the crypts as multiple pus points.
  • 10. SIGNS & SYMPTOMS OF TONSILLITIS Symptoms Sore throat Difficulty in swallowing Fever Earache     General symptoms : headache, Signs Hyperemia of the pillars, Soft palate and uvula Red, swollen tonsils with yellowish spots of Purulent material or Whitish membrane on medial surface of tonsils bodyache, Malaise Breath is fetid  Coated tongue     Enlarged and tender lymphnodes PRESENTATIONTITLE 10
  • 11. Risk Factors Acute Tonsillitis 11 Predisposed factors of tonsillitis:-  Extremes of age group  Immunocompromised individuals (diabetics, organ transplant or chemotherapeutic patients)  Abnormal tonsils form previous recurrent tonsillitis  Generalized pharyngitis  Overcrowding, poor nutrition, inadequate ventilation  Exposure to cold
  • 12. COMPLICATIONS 12  Chronic tonsillitis  Pharyngeal abscess  Rheumatic fever  Endocarditis  Peritonsillar abscess  Cervical abscess  Acute Otitis media  Sinusitis
  • 13. PHARYNGITIS It is the inflammation of the pharynx, resulting in a sore throat The symptoms in pharyngitis are similar to that in tonsillitis including pain, fever, dysphagia, swollen lymph nodes in neck, and a headache or earache WHY WE INCLUDED WHY WE EXCLUDED SYMPTOMS such as: • Sudden onset • Soreness • High fever • NO HISTORY OF: • Allergy / post nasal drip • GERD • Smoking No sign of: • Tonsillopharyngeal petechiae (streptococcal) • Tonsillopharyngeal exudate 13
  • 14. Differential diagnosis of sore throat and fever 1. Tonsillitis 2. Influenza virus 3. Pharyngitis 4. Corona virus 5. Adenoiditis 6. Peritonsillar abscess 7. Trauma/foreign body. 8. Squamous cell carcinoma of tonsil.
  • 15. Differentiate between viral upper respiratory tract infection from bacterial pharyngitis / tonsillitis 15
  • 16. History questions to ask to elicit such a diagnosis 1. What has been the duration of sore throat and how did it start? 2. Ask whether it is aggravated from anything or relieved by anything or not? 3. If there is any sputum production along with sore throat or not? 4. Dysphagia? 5. Any associated symptoms or pain? 6. Did the fever start simultaneously or not? 7. If the fever was continuous ore intermittent? 8. History of allergies? 9. History of any previous URTIs? 10. Any smoking habits or not?
  • 18. LAB INVESTIGATION Complete Blood Count To determine whether the infection acute or chronic Culture To identify the causative organism using throat swab Rapid Antigen test Involves a quick throat swab. Within minutes, the test can show the presence of group A streptococcus bacteria EXAMINATION  Use a head mounted light to inspect the patient  Check for any swellings, scar marks, discoloration or discharge  Gently palpate and look for any tenderness or swollen lymph nodes. 17
  • 19. Management Of Tonsillitis MEDICAL  Treatment of tonsillitis depends on the cause  Provide adequate fluids intake to keep throat moist and prevent dehydration.  Saltwater gargle.  Analgesics (paracetamol) is given according to patient’s age to relieve fever and local pain.  Antibiotics in case of bacterial infections  Most of infections are due to streptococcus species. Penicillin or Amoxicillin is the drug of choice and patient allergic to penicillin is treated with Erythromycin or Azithromycin.  Amoxicillin for 7 to 10 days. Azithromycin 3-5 days
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  • 22. SURGICAL . Tonsillectomy:- It is a surgical procedure to remove tonsils. Indications :  Tonsil / adenoid hypertrophy with sleep apnea syndrome  Hypertrophy causing dysphagia with associated weight loss  Excisional biopsy for suspected malignancy (lymphoma)  Recurrent tonsillitis 19
  • 23. Other methods for tonsillectomy. PRESENTATIONTITLE 23 1. Electrocautery 2. Laser tonsillectomy 3. Intracapsular tonsillectomy 4. Harmonic scalpel 5. Plasma-mediated ablation technique 6. Coblation tonsillectomy 7. Cryosurgical technique
  • 24. COMPLICATIONS OF TONSILLECTOMY PRESENTATIONTITLE 24 A. IMMEDIATE 1.Primary haemorrhage 2.Reactionary haemorrhage 3.Injury to tonsillar pillars, uvula, soft palate, tongue or superior constrictor muscle due to bad surgical technique 4. Injury to teeth 5. Aspiration of blood 6. Facial oedema 7. Surgical emphysema B. DELAYED 1. Secondary haemorrhage. 2. Infection. 3. Lung complications 4. Scarring in soft palate and pillars. 5. Tonsillar remnants.
  • 25. Prescription for viral URTI The basic treatment for viral upper respiratory infections is : Analgesics : acetaminophen, NSAIDs. Antihistamine : CHLOPHEDIANOL, DEXBROMPHENIRAMINE is a cough suppressant and antihistamine. Nasal decongestant sprays: pseudoephedrine, and phenylephrine.
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