Constraint-induced movement therapy (CIMT) is a rehabilitation technique used to treat learned non-use after stroke. CIMT involves repetitive task practice with the affected limb while constraining the unaffected limb. Various protocols have been developed involving different levels of task practice intensity and constraint duration. Recent research shows CIMT improves neurophysiological and kinematic measures correlated with motor function recovery, such as increased brain gray matter and cortical activation, more efficient movements, and improved real-world arm use. CIMT aims to counteract learned non-use and promote increased movement of the affected limb through intensive task practice and constraint of the unaffected limb.