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The document discusses two conditions related to the endocrine system: polyuria and polydipsia. Polyuria is the excessive release of large volumes of urine, more than 2.5 L per day in adults, and can be caused by too much fluid, salt, or sugar intake, diuretic drugs, diabetes, renal failure, sickle cell anemia, or radiographic procedures using contrast media. Polydipsia is excessive thirst and can result from decreased blood volume, diabetes, certain drugs, loss of body fluids from conditions like sepsis, burns, or organ failure. Frequent urination and pronounced thirst are indicators of diabetes due to the kidneys' inability to conserve water. A doctor should be called if ur



