Melanoma is a type of skin cancer that can be deadly if not detected early. It is important to protect skin from UV radiation by wearing sunscreen, limiting sun exposure, and wearing protective clothing. Getting regular skin exams is key to detecting melanoma or other skin cancers early before they become life threatening. Prevention through sun protection and skin self-exams can help reduce skin cancer risk.
The diagnosis and treatment of nonmelanoma skin cancers in the U.S. increased by 77 percent between 1994 and 2014. ... Basal cell carcinoma (BCC) is the most common form of skin cancer. An estimated 4.3 million cases of BCC are diagnosed in the U.S. each year resulting in more than 3,000 deaths.
Designed by Rachel Uttenburg/John NEwqusit
The diagnosis and treatment of nonmelanoma skin cancers in the U.S. increased by 77 percent between 1994 and 2014. ... Basal cell carcinoma (BCC) is the most common form of skin cancer. An estimated 4.3 million cases of BCC are diagnosed in the U.S. each year resulting in more than 3,000 deaths.
Designed by Rachel Uttenburg/John NEwqusit
Early Detection of Melanoma and Other Skin CancersSummit Health
This lecture provides an overview of skin cancer including risks, early detection, and treatment. Learn to identify the early signs of skin cancer. Melanoma and non-melanoma skin tumors will be discussed and prevention of skin cancer will be emphasized.
From Queens Library's expert-led panel, Cancer Awareness: What You Need to Know, featuring professionals from New York Hospital Queens, North Shore LIJ, the American Cancer Society, and the Leukemia and Lymphoma Society
Early Detection of Melanoma and Other Skin CancersSummit Health
This lecture provides an overview of skin cancer including risks, early detection, and treatment. Learn to identify the early signs of skin cancer. Melanoma and non-melanoma skin tumors will be discussed and prevention of skin cancer will be emphasized.
From Queens Library's expert-led panel, Cancer Awareness: What You Need to Know, featuring professionals from New York Hospital Queens, North Shore LIJ, the American Cancer Society, and the Leukemia and Lymphoma Society
The Pathankot attack is not a spontaneous response to recent developments; it is a manifestation of Pakistan’s national security strategy to pursue its revisionist agenda against India, says C Christine Fair, author of Fighting to the End: The Pakistan Army’s Way of War, and an associate professor in the Peace and Security Studies Programme at Georgetown University’s Edmund A Walsh School of Foreign Service. Fair, who earlier served as a political officer to the UN Assistance Mission to Afghanistan in Kabul, tells Bhaswar Kumar in a telephonic interview that there is a consensus within the Indian security establishment that India lacks the offensive capability to defeat Pakistan in a short war.
Conception de Réseau WiFi avec AirMagnet PlannerSyNAP Services
Lors de la conception de réseau wifi, les ingénieurs réseau ont besoin d’un outil qui prend en compte les matériaux de construction, les obstacles, la configuration des bornes wifi, les types d’antenne wifi, et une foule d’autres paramètres pour fournir la meilleure architecture possible avant même qu’elle ne soit déployée physiquement ou que le bâtiment lui-même soit construit.
Apprenez comment estimer le budget et la faisabilité de votre projet réseau Wifi et éviter d’engager votre responsabilité dans des décisions prises à l’aveugle.
Under mentioned 21 questions must be asked and answered for our goals to be 1.Outcome focused: Once you understand your WHY (and it's an enthusiastic WHY) you're 90% there! 2.In line with your values: The more a goal aligns with your inner or core values - the EASIER it will be to achieve.( NOTE: We can achieve goals that don't align with our values but it's harder to do and less satisfying.)3.Stated in the positive : ie. "I want healthy fingernails" rather than "I want to stop biting my nails" And 4.SMART
Skin cancer- what is skin cancer, its risk factorsdraishwarya326
Skin cancer is a condition characterized by the abnormal growth of skin cells, typically as a result of exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. This abnormal growth leads to the formation of tumors or lesions on the skin, which can vary in size, shape, and color. Skin cancer is the most common type of cancer worldwide, with millions of cases diagnosed each year.
All You Need to Know About Melanoma/Skin CancerEPIC Health
It may not be possible to prevent the onset of skin cancer completely, but we can certainly mitigate the risk factors that are within our control. View these slides to know more
Skin Cancer is the abnormal growth of skin cells and most often develops on skin exposed to the sun. But this common form of cancer can also occur on areas of your skin not ordinarily exposed to sunlight.
Purpose:
The purpose of this webinar is to spread awareness among the people about skin cancer and it is also one of the most preventable cancers. By sharing facts about the dangers of unprotected sun exposure and encouraging people to check their skin for warning signs, we can and will save lives.
Skin cancer is by far the most common type of cancer. If you have skin cancer, it is important to know which type you have because it affects your treatment options and your outlook (prognosis). If you aren’t sure which type of skin cancer you have, ask your doctor so you can get the right information.
https://indianmedtrip.com/treatments/skin-cancer-treatment-in-india/
Dr. Ana Ciurea presents the basics of melanoma preventio, screening and diagnosis at the MRF's Patient Symposium at MD Anderson Cancer Center on January 31, 2015.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
2. Background leading to theBackground leading to the
problemproblem
• Lack of Knowledge
“No big deal?”
YES! It is a big deal.
Types include:
• Basil Cell
• Melanoma
• Squamous Cell
3. Types of Skin CancerTypes of Skin Cancer
Basal cell carcinoma
Squamous cell
carcinomas
4. Types of Skin CancerTypes of Skin Cancer
Malignant Melanoma
5. Other Effects From the SunOther Effects From the Sun
• Skin Damage
• Cataracts and Other Eye Damage
• Immune Suppression
6. Other ProblemsOther Problems
In terms of cancer types; skin cancer historyIn terms of cancer types; skin cancer history
was most strongly tied to liver cancer,was most strongly tied to liver cancer,
followed by Hodgkin disease, leukemia, andfollowed by Hodgkin disease, leukemia, and
lung cancer.lung cancer.
Women who have had the most commonWomen who have had the most common
forms of skin cancer are 2.3 times as likely toforms of skin cancer are 2.3 times as likely to
also get deadlier cancers such as breast,also get deadlier cancers such as breast,
lung, and colon.lung, and colon.
7. Possible SolutionsPossible Solutions
• Don’t sunbathe
• Avoid sun exposure between 10:00 a.m. – 4:00
p.m.
• When outdoors use SPF 15 or higher
without SPF 15 reddening takes 20 mins
with SPF 15 reddening takes 5 hours (reapply
every 2 hours & after swimming)
Several sunburns over course of a lifetime can
double/ triple melanoma risk no matter when
sunburns occurred
8. Possible SolutionsPossible Solutions
• Wear long pants, long-sleeved shirts, hats, UV-
protective sunglasses
• Stay away from artificial tanning devices
• Teach children good sun protection habits at an
early age. Damages that lead to adult skin
cancers start in childhood
• Examine self from head to toe once every 3
months
• Tinted windows in automobile
9. Variety of ApproachVariety of Approach
• UVB causes basal,
squamous cell
carcinomas and
melanoma.
• UVA causes
wrinkling, leathering,
photo aging because
it penetrates deeper
and exacerbates UVB
effects.
10. The ABCD’s of Skin CancerThe ABCD’s of Skin Cancer
• A – Asymmetry
• B – Border
• C – Color
• D – Diameter
11. TreatmentsTreatments
• Removal – Laser /
Excision or cutting out
• Surgery – lymph
nodes
• Chemotherapy /
Immunotherapy
• Benign / Malignant
12. Best ProtectionBest Protection
• Besides using a sunscreen with an SPF of
15 or higher, a regularly scheduled full-
body exam by your health care
professional is key to prevention!
– This is because melanoma can occur on
areas of your body that are not exposed to the
sun.
– It often takes a trained eye to spot melanoma
in early stages.
13. Self ExaminationSelf Examination
• You should examine
yourself regularly
• The best time to do this is
after a bath or shower,
standing in front of a full
length mirror.
• Use a handheld mirror to
help you view areas that
are difficult to see.
• If you notice any odd-
looking mole or marking,
contact your doctor
ASAP!
14. PreventionPrevention
• Sun Block
• Reduce your Exposure of the Sun
• Protective Clothing
• Self Exam
• Dermatology visits
• Education and Awareness
