The document discusses the transition to the "third era of IT" and outlines three things that are important for CIOs in this era. 1) Deeply understand how your business creates value. 2) Align your IT strategy with the business's value creation problem. 3) Embrace the new normal in IT, which includes increased use of cloud computing, mobile access, and more agile and scalable systems. The document provides examples of how one company, McKesson, is making this transition by moving more applications to SaaS and cloud platforms over time to improve agility, reduce costs, and better support the business.