This document provides an overview of events related to exposures to select agents at Texas A&M University's biodefense research laboratories. It discusses the characteristics of select agents and regulations governing their use. It describes safety protocols for BSL-3 laboratories and summarizes inspections that found issues with Texas A&M's brucellosis and Coxiella research resulting in researcher exposures. The document also provides background on the university and its biodefense research programs.
Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. These prevention mechanisms include conduction of regular reviews of the biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety also means safety from exposure to infectious agents.
Necessity
In order to avoid infection/biohazard to the laboratory personnel & the environment, biosafety levels are very important.
Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. These prevention mechanisms include conduction of regular reviews of the biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety also means safety from exposure to infectious agents.
Necessity
In order to avoid infection/biohazard to the laboratory personnel & the environment, biosafety levels are very important.
This presentation is all about Biosafety - Rules & Regulations at both National & International levels.... All you need to know about BIOSAFETY ... The ppt will allow you to access the vast Biological procedures around globe.
Current Status and Future Prospects for Infection Control with Optical RadiationWilliam Bahnfleth
Control of viral and bacterial pathogens in the built environment is an important aspect of indoor environmental quality with severe personal and economic consequences. Diminished quality of life, premature mortality, decreased worker productivity, and increased healthcare costs are all possible outcomes. Healthcare environments are particularly at risk due to the state of health of patients and the prevalence of increasingly drug-resistant pathogens. The World Health Organization (WHO) estimates that in developed countries, 7% hospital patients overall and roughly 30% of intensive care unit patients will contract at least one healthcare acquired infection (HAI) during their stay. The role of heating, ventilation, and air-conditioning systems in an infection control program is to prevent exposure through a combination of ventilation, pressurization, compartmentalization, and air treatment. By lowering airborne loadings of infectious aerosols, a beneficial effect may be achieved with respect to both inhalational and intermediate surface (fomite) transmission. These measures are becoming of greater importance as the ability to stop infections with drug therapy (e.g., the use of antibiotics for bacterial infections) decreases. Conventional approaches include the use of large quantities of outside air and high air change rates, which increase energy use in combination with high efficiency filters. It has been known for nearly a century that certain wavelengths of light have germicidal capability that is not affected by drug resistance. In particular, optical radiation in the UVC band, particularly 254 nm UVC produced by low pressure mercury vapor lamps has been used to good effect not only for air disinfection, but also as an adjunct to surface disinfection using oxidants and other cleaning materials. This presentation summarizes the state of the art with respect to technology and applications, surveys available evidence of effectiveness, and discusses the potential of future developments. The context is primarily healthcare facilities, but with applicability to other types of residential and non-residential facilities.
This presentation is all about Biosafety - Rules & Regulations at both National & International levels.... All you need to know about BIOSAFETY ... The ppt will allow you to access the vast Biological procedures around globe.
Current Status and Future Prospects for Infection Control with Optical RadiationWilliam Bahnfleth
Control of viral and bacterial pathogens in the built environment is an important aspect of indoor environmental quality with severe personal and economic consequences. Diminished quality of life, premature mortality, decreased worker productivity, and increased healthcare costs are all possible outcomes. Healthcare environments are particularly at risk due to the state of health of patients and the prevalence of increasingly drug-resistant pathogens. The World Health Organization (WHO) estimates that in developed countries, 7% hospital patients overall and roughly 30% of intensive care unit patients will contract at least one healthcare acquired infection (HAI) during their stay. The role of heating, ventilation, and air-conditioning systems in an infection control program is to prevent exposure through a combination of ventilation, pressurization, compartmentalization, and air treatment. By lowering airborne loadings of infectious aerosols, a beneficial effect may be achieved with respect to both inhalational and intermediate surface (fomite) transmission. These measures are becoming of greater importance as the ability to stop infections with drug therapy (e.g., the use of antibiotics for bacterial infections) decreases. Conventional approaches include the use of large quantities of outside air and high air change rates, which increase energy use in combination with high efficiency filters. It has been known for nearly a century that certain wavelengths of light have germicidal capability that is not affected by drug resistance. In particular, optical radiation in the UVC band, particularly 254 nm UVC produced by low pressure mercury vapor lamps has been used to good effect not only for air disinfection, but also as an adjunct to surface disinfection using oxidants and other cleaning materials. This presentation summarizes the state of the art with respect to technology and applications, surveys available evidence of effectiveness, and discusses the potential of future developments. The context is primarily healthcare facilities, but with applicability to other types of residential and non-residential facilities.
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A quick list of things for professionals who want more out of life than just hanging out in clubs.
The document provides a detailed overview on the basic principles of operating a biotech or micro laboratory along with basic techniques with which to handle organisms, chemicals &equipment and ensuring your own, your colleagues and your environment's safety.
this lecture give general overview on BIORISK management
as :
Contaminant principles and practices that are implemented to prevent the unintentional exposure to pathogens and toxins, or their accidental release defined as Biosafety
principles, technologies and practices and strategies aimed at minimizing the intentional misuse and release of a biological agent defined as Biosecurity
The Laboratory biosafety emphasizes the use of good microbiological practices, appropriate containment equipment, proper facility design, operation/maintenance and administrative considerations to minimize the risk of worker injury or illness.
Its all about Bio terrorism. Here i am trying to involve all content(maximum) those are available on online like ready.gov; CDC. i think it will cover all information that are need to know.
According to the Centre Of Disease Control and Prevention (CDC), Biosafety is the application of safety precautions that reduce a laboratorian’s risk of exposure to a potentially infectious material and limit contamination of the work environment and ultimately the community.
CDC Director Releases After-Action Report on Recent Anthrax Incident; Highlights Steps to Improve Laboratory Quality and Safety http://www.cdc.gov/od/science/integrity/docs/Final_Anthrax_Report.pdf
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
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Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
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Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
1. Fall From Grace Texas A&M University’s Biodefense & Infectious Disease Research Labs Presented By Malcolm Smith November 1 st 2007
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7. Bio-Safety Level The biosafety level assigned to an agent is based on the activities typically associated with the growth and manipulation of the quantities and concentrations of infectious agents required to accomplish identification or typing. If activities with clinical materials pose a lesser risk to personnel than those activities associated with manipulation of cultures, a lower biosafety level is recommended. On the other hand, if the activities involve large volumes and/or concentrated preparations ("production quantities"), or manipulations which are likely to produce aerosols or which are otherwise intrinsically hazardous , additional personnel precautions and increased levels of primary and secondary containment may be indicated. BMBL 4 th Edition Explanation
14. The Sunshine Project The Sunshine Project is an international non-governmental organization dedicated to upholding prohibitions against biological warfare and, particularly, to preventing what it sees as military abuse of biotechnology . With offices in Austin, TX and Hamburg, Germany, the Sunshine Project works by exposing research on biological and chemical weapons . Typically, it accesses documents under the Freedom of Information Act and other open records laws, publishing reports and encouraging action to reduce the risk of biological warfare . It tracks the construction of high containment laboratory facilities and the dual-use activities of the U.S. biodefense program. http://www.sunshine-project.org/ Background
15. Noteworthy Individuals Director of the US Office of the Sunshine Project. Holds two Master's degrees from the University of Texas at Austin and worked on biotechnology-related policy since 1993. Hammond is a member of the Pugwash Study Group on the Chemical and Biological Weapons Conventions. Hammond directs the Sunshine Project in the US and manages its research program on biodefense, incapacitants, and other issues Edward Hammond
34. May 17 th 2007 – TAMU responds to CDC facility inspection report June July 18 th 2007 – Office of Inspector General notifies TAMU that they may be liable for civil penalties up to $750,000 for violating federal Select Agent Rule June 26 th 2007 – Sunshine Project Releases a report that three laboratorians were infected with Coxiella burnetti and noted high blood titers for the agent on April 3 rd 2006 June 30 th 2007 – CDC issues a “Cease and Desist Order” to TAMU for all Select Agent Work July 23 rd 2007 – CDC has a follow-up inspection of TAMU’s Select Agent Program August 17 th 2007 – TAMU proposes a settlement of $10,000 to the Office of the Inspector General for violation of Select Agent Rule August 31 st 2007 – CDC issues a Facility Inspection Report to TAMU citing 32 “observations” and asks TAMU to respond. Following TAMU response a follow-up inspection will be conducted to investigate facility Incident Timeline
35. Both the RO (August 2007) and the ARO/Biosafety Officer (September 2007) resign their post at TAMU Incident Timeline
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