This document discusses the significance of tree-ring data in understanding paleoclimate and paleoecology, emphasizing the relationship between tree growth and cosmic radiation as well as climate factors like the Atlantic Multidecadal Oscillation. It highlights the necessity of addressing false discovery rates in the analysis of large-scale dendrochronology data, proposing approaches such as statistical simulations and forward modeling. The document underscores the importance of accurately interpreting tree-environment relations in the context of a vast global ring-width network.