The spleen is a wedge-shaped lymphatic organ located in the left hypochondrium. It acts as a filter for the blood and plays an important role in immune responses. The spleen is usually about 12.5 cm long, 7.5 cm broad, and 2.5 cm thick. It receives its blood supply from the splenic artery and drains into the portal vein. The spleen filters old red blood cells from the blood and aids in phagocytosis, hematopoiesis, and immune responses. Clinical issues involving the spleen include splenomegaly, splenectomy, and splenic puncture or infarction.