This document covers the anatomy and biomechanics of the spine. It discusses the anatomy of the cervical, thoracic, and lumbar regions of the spine. It also covers the clinically significant muscles attached to the spine and their functions. Additionally, it examines the kinematics (motions) and kinetics (forces) of the spine, including flexion, extension, lateral flexion, axial compression, bending, torsion, and shear. Finally, it outlines Fritz's three laws of spinal biomechanics regarding neutral and non-neutral mechanics and how motion in one plane modifies motion in other planes.