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Sherrington’s Law
Sherrington’s Law of Reciprocal Innervation
Whenever an agonist receives an impulse to contract, an equivalent inhibitory
impulse is sent to its antagonist, which relaxes and actually lengthens
• Agonist Muscles
− AKA prime mover
− On contracting it automatically is checked and controlled by the opposing simultaneous
contraction of another muscle
• Antagonist Muscles
− An agent that acts in physiological opposition
− A muscle that contracts and limits the action of an agonist with which it is paired
Important Concepts to Understand
• Synergistic Muscles
−Two muscles moving the eye in the same direction
• Yolk Muscles
−AKA Contralateral Synergists
−Pair of muscles producing conjugate ocular movements
Important Concepts to Understand
Right Eye Left Eye Movement Position of Gaze
Lateral Rectus Medial Rectus Move the globe to the right Dextroversion
Medial Rectus Lateral Rectus Move the globe to the left Laevoversion
Superior Rectus Inferior Oblique Move the globe upward Dextroelevation
Inferior Oblique Superior Rectus Move the globe upward Laevoelevation
Superior Oblique Inferior Rectus Move the globe downward Laevodepression
Inferior Rectus Superior Oblique Move the globe downward Dextrodepression
Paired Agonist Muscles
Eye movements previously mentioned visible via motility test
Physiologically and clinically important because it explains why
strabismus occurs due to paralysis of extraocular muscle
Importance of Sherrington’s Law
• Measure electrical potential changes within a muscle based on muscle fibre
contraction indicating overall neuromuscular activity
Electromyography (EMG)
• Uses:
−Strabismus
−Patients with Duane’s Syndrome
Sherrington’s Law – Clinical Use
Duane’s Syndrome
• Not only applicable to EOM
• It applies to all striated muscles of the body
Something to Take Home
• http://www.cybersight.org/bins/content_page.asp?cid=735-2858-4397-4404-
4654-4704-4707
• http://www.vestib.com/EOM-muscles-movements.html
• http://onlinelibrary.wiley.com/doi/10.1111/j.1442-9071.1982.tb01632.x/pdf
• http://www.authorstream.com/Presentation/optom.rawaa-513087-4th-
lecture/
• https://books.google.gy/books?id=DN60U5yZkyQC&pg=PA63&lpg=PA63&dq=s
herrington+law+muscles&source=bl&ots=_bIrlBf7_d&sig=mpcXewinO1L7NwpY
6B84Q4h3tS0&hl=en&sa=X&ved=0CCEQ6AEwAjgKahUKEwiRgp2h8tzIAhXHGh4
KHSheDNc#v=onepage&q=sherrington%20law%20muscles&f=false
Reference

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Sherrington’s Law

  • 2. Sherrington’s Law of Reciprocal Innervation Whenever an agonist receives an impulse to contract, an equivalent inhibitory impulse is sent to its antagonist, which relaxes and actually lengthens
  • 3. • Agonist Muscles − AKA prime mover − On contracting it automatically is checked and controlled by the opposing simultaneous contraction of another muscle • Antagonist Muscles − An agent that acts in physiological opposition − A muscle that contracts and limits the action of an agonist with which it is paired Important Concepts to Understand
  • 4. • Synergistic Muscles −Two muscles moving the eye in the same direction • Yolk Muscles −AKA Contralateral Synergists −Pair of muscles producing conjugate ocular movements Important Concepts to Understand
  • 5. Right Eye Left Eye Movement Position of Gaze Lateral Rectus Medial Rectus Move the globe to the right Dextroversion Medial Rectus Lateral Rectus Move the globe to the left Laevoversion Superior Rectus Inferior Oblique Move the globe upward Dextroelevation Inferior Oblique Superior Rectus Move the globe upward Laevoelevation Superior Oblique Inferior Rectus Move the globe downward Laevodepression Inferior Rectus Superior Oblique Move the globe downward Dextrodepression Paired Agonist Muscles
  • 6. Eye movements previously mentioned visible via motility test
  • 7. Physiologically and clinically important because it explains why strabismus occurs due to paralysis of extraocular muscle Importance of Sherrington’s Law
  • 8. • Measure electrical potential changes within a muscle based on muscle fibre contraction indicating overall neuromuscular activity Electromyography (EMG)
  • 9. • Uses: −Strabismus −Patients with Duane’s Syndrome Sherrington’s Law – Clinical Use
  • 11. • Not only applicable to EOM • It applies to all striated muscles of the body Something to Take Home
  • 12. • http://www.cybersight.org/bins/content_page.asp?cid=735-2858-4397-4404- 4654-4704-4707 • http://www.vestib.com/EOM-muscles-movements.html • http://onlinelibrary.wiley.com/doi/10.1111/j.1442-9071.1982.tb01632.x/pdf • http://www.authorstream.com/Presentation/optom.rawaa-513087-4th- lecture/ • https://books.google.gy/books?id=DN60U5yZkyQC&pg=PA63&lpg=PA63&dq=s herrington+law+muscles&source=bl&ots=_bIrlBf7_d&sig=mpcXewinO1L7NwpY 6B84Q4h3tS0&hl=en&sa=X&ved=0CCEQ6AEwAjgKahUKEwiRgp2h8tzIAhXHGh4 KHSheDNc#v=onepage&q=sherrington%20law%20muscles&f=false Reference

Editor's Notes

  1. NB: Sherrington’s law applies to muscles of one eye. Applies to both versions and vergences
  2. Agonist Muscles: The mover muscle producing the movement Antagonist Muscle: Produces a movement in the direction opposite Example: Right MR and Right LR
  3. Synergist Example: Right SR and Right IO act synergistically to produce elevation Yolk Muscles: Muscles that cause movement in the same direction Example: Right SO and Right IO
  4. Dextroversion: Looking to the right Laevoversion: Looking to the left