The spinal cord can be damaged through trauma, compression, or disease. Traumatic injuries are usually due to accidents and can result in paralysis depending on the location and severity of the injury. Spinal cord compression may be caused by fractures, tumors, or infections and can also lead to paralysis or loss of sensation if not addressed. The most serious injury is complete transection of the spinal cord, resulting in paralysis and loss of sensation below the level of injury.