This document summarizes a study identifying new sources of resistance to stripe rust in synthetic hexaploid wheat. Stripe rust is a major wheat disease that causes significant yield losses in Ethiopia. The study evaluated 764 synthetic hexaploid wheat lines for resistance to stripe rust through seedling and field tests in Ethiopia and Syria. 173 lines exhibited resistance or moderate resistance at the adult plant stage across locations. Some resistant lines were also resistant to stem rust. The synthetic hexaploid wheat lines identified in this study provide potential new sources of resistance that can be used in wheat breeding programs to develop cultivars with improved resistance to stripe rust.