This document discusses how drug use impacts individuals and society. It notes that drug use can result in deaths, emergency room visits, lost productivity, broken homes, and higher medical costs. Surveys, reports, and questionnaires are used to track drug use trends over time. The document outlines various patterns of drug use and how perceptions of dependence have changed over time. It discusses how drug use can negatively impact families, social behavior, education attainment, employment, and fetal development. Testing methods and their limitations are also reviewed.