Allah assures that He is near to those who call upon Him in prayer and supplication. He responds to the calls of those who pray to Him and believe in Him, so that they may follow the right path. The verse emphasizes that true satisfaction comes from developing a close connection to Allah through prayer and obedience to His commands, rather than focusing on His unknowable essence. While Allah is always near to respond to supplication, He reminds believers that they too must respond to His call through faith and righteous actions.