Radiology for Radiation Oncologists
Skull base radiology
Dr Kanhu Charan Patro
MD,DNB[RADIATION ONCOLOGY],MBA,CEPC,PDCR
HOD, Radiation Oncology
MGCHRI, Visakhapatnam, INDIA
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Why a radiation oncologist need it?
• Some head and neck cancers having perineural spread
• Para nasal sinus
• Nasopharynx
• Salivary gland
• Buccal mucosa
• Complex nature of skull base area
• Some tumors like schwannoma arise from cranial nerves
• Some functional issues like trigeminal neuralgia need SRS
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The complex anatomy
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Buccal mucosa with intracranial extension
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Parotid with intracranial spread
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Nasopharynx with sphenopalatine foramen
(SPf) left
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Maxilla with Pterygo palatine fossa invasion
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Normal skull base
• Extend – root of nose anteriorly to the superior nuchal line posteriorly
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Structures and contents
• BONES
• Fossa
• Foramen
• Fissure
• Canal
• CONTENTS
• Ganglion
• Nerve
• Vessel
• Vein
• Artery
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What to see?
• FORAMINA
• SUTURES
• CANALS
• FISSURES
• FOSSES
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Normal skull base
• 5 bones:
– Frontal
– Ethmoid
– Sphenoid
– Temporal
– Occipital
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Two ridges Sphenoid ridge
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3 fossae
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Ethmoid bone
• Cribriform plate is perforated by
approx 20 holes on each side of
the crista galli
• Nerve fibres of olfactory nerve (CN I)
pass from nasal mucosa to olfactory
bulb
• Crista galli serves as the anchor for
anterior margin of the falx cerebri
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Normal skull base
• Most important part:
– Basisphenoid (anterior aspect of sella)
– Basiocciput (posterior lip of the foramen magnum)
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Sphenoid bone
• 3 compartments:
– Basisphenoid:
• Dorsum sella, posterior clinoids, sella turcica,
tuberculum sella, sphenoid sinus
• Fused to clivus in adult
– Greater wing of sphenoid
• Medial two-thirds and anterior wall of the middle
cranialfossa floor
– Lesser wing of sphenoid
• Medial and superior aspects of the anterior wall of
the middle cranial fossa and the anterior clinoids
• Superior and medial edgesof the superior orbital
fissure
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Anterior view
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Superior view
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Posterior view
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Anterior fossa foramina
• Foramen cecum
• ANTERIOR ETHMOIDAL FORAMEN
• Foramen cribriform
• POSTERIOR ETHMOIDAL FORAMEN
• ORBITO MENINGEAL FORAMEN
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Foramen cecum
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Foramen cecum
Content
• Emissary veins to superior
sagittal sinus from the upper
part of the nose
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Cribriform foramen
Content
• Olfactory nerve bundles (I)
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Anterior and posterior ethmoidal foramen
Content
• Anterior ethmoidal foramen
• Anterior ethmoidal artery
• Anterior ethmoidal vein
• Posterior ethmoidal foramen
• Posterior ethmoidal artery
• Posterior ethmoidal vein
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Supraorbital foramen
Content
• Supraorbital artery supraorbital
vein
• Supraorbital nerve
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Middle cranial fossa foramina
• Superior orbital fissure
• Inferior orbital fissure
• Optic canal
• Foramen rotundum
• Foramen ovale
• Foramen lacerum
• Foramen spinosum
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Superior orbital fissure
Content
• Superior ophthalmic vein
• Inferior ophthalmic veins
• Oculomotor nerve (III)
• Trochlear nerve (IV)
lacrimal, frontal
• Nasociliary branches
of ophthalmic nerve (V1)
• Abducent nerve (VI)
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Inferior orbital fissure
Content
• Inferior ophthalmic veins
infraorbital artery
infraorbital vein,
• Tributary of pterygoid plexus
• Zygomatic nerve and infraorbital
nerve of maxillary nerve (V2)
• Orbital branches
of pterygopalatine ganglion
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Optic canal
Content
• Ophthalmic artery
• Optic nerve (II)
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Foramen rotundum
Content
• Maxillary nerve (V2)
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Foramen ovale
Content
• Accessory meningeal artery,
• Emissary vein connecting cavernous
sinus with pterygoid plexus
• Mandibular nerve (V3)
• Lesser petrosal nerve
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Foramen lacerum
Content
• Artery of pterygoid canal,
• Meningeal branch of ascending
pharyngeal artery,
• Emissary vein
• Nerve of pterygoid
canal through its anterior wall
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Foramen spinosum
Content
• Middle meningeal artery
• Meningeal branch of the
mandibular nerve (V3)
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Posterior cranial fossa foramina
• Internal auditory meatus
• Jugular Foramen
• Hypoglossal canal
• Foramen magnum
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Internal auditory meatus
Content
• Labyrinthine artery
• Facial nerve (VII),
• Vestibulocochlear nerve (VIII)
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Jugular foramen
Content
• Internal jugular vein,
• Inferior petrosal sinus,
• Sigmoid sinus
• Glossopharyngeal nerve (IX),
• Vagus nerve (X),
• Accessory nerve (XI)
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Hypoglossal canal
Content
• Hypoglossal nerve
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Foramen magnum
Content
1. Anterior and posterior spinal
arteries, vertebral arteries
2. Lowest part of medulla
oblongata, three meninges,
ascending spinal fibers
of accessory nerve (XI)
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OVALE OVAL
MAGNUM MAGNA
ROTUNDUM ROUND
LACERUM LARGE
SPINOSUM SMALL
SUPERIOR ORBITAL FISSURE SUPERIOR
INFERIOR ORBITAL FISSURE INFERIOR
OPTIC CANAL CANAL
VIDIAN CANAL CANAL
SOFTWARERadiAnt DICOM
Viewer (64-bit).lnk
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Pterygomaxillary area
• Pterygopalatine fossa
• Pterygomaxillary fissure
• Sphenopalatine foramen
• Sphenopalatine ganglion
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Pterygopalatine fossa
https://radiopaedia.org/cases/ct-head-bone-window-axial-
skull-base-labelling-questions?lang=gb 61
Pterygopalatine ganglion
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Sphenopalatine foramen opens to nasal cavity
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Vidian canal
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Stylomastoid foramen
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Inferior opthalmic vein
Drains via:
Sphenoparietal sinus
Petrosal sinuses
Basilar plexus
Connection:
Contains:
Pterygoid plexus
Circular sinus
CN III, IV, V1, V2, VI
Skull Base Anatomy
Cavernous Sinus
Receives: Superior opthalmic vein
Meckel’s Cave
• Posterior aspect of cavernous sinus
• Gasserian ganglion (sensory root ganglion of CN V)
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Origin of cranial nerves
1. Magnetic resonance imaging (MRI) is the gold standard
technique in the study of the cranial nerves
2. Steady-state free procession (SSFP) images are the best
sequences for the visualization of the cisternal segments
showing dark cranial nerves against a background of bright
cerebrospinal fluid (CSF)
3. Computed tomography (CT) can be useful to evaluate
intraosseous segments of cranial nerves, skull base
foramina, and bony traumatic lesions
https://mrimaster.com/anatomy%20brain%20cranial%20nerves
.html for cranial nerve
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Olfactory nerve
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2nd cranial nerve
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3rd cranial nerve
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4th cranial nerve
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5th cranial nerve
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6th cranial nerve
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7th and 8th cranial nerve
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9th ,10th and 11th cranial nerve
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12th cranial nerve
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softwareRadiAnt DICOM Viewer (32-bit).lnk
SLICE BY SLICE DOWN TO UP
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LEVEL-1
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MANDIBLE, CORONOID PROCESS
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Mandible, neck
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MASTOID PROCESS
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OCCIPITAL CONDYLE
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PTERYGOMAXILLARY FISSURE
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PTERYGOPALATINE FOSSA
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PTERYGOID PLATES
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PTERYGOID PROCESS
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STYLOID PROCESS
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LEVEL-2
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MANDIBLE CONDYLE
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MASTOID
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OCCIPITAL CONDYLE
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PTERYGO MAXILLARY FISSURE
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PTERYGOPALATINE FOSSA
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PTERYGOID PLATES
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PTERYGOID PROCESS
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STYLOID PROCESS
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LEVEL-3
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MASTOID PROCESS
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OCCIPITAL BONE
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OCCIPITOMASTOID SUTURE
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PTERYGOMAXILLARY FISSURE
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PTERYGOPALATINE FOSSA
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PTERYGOID PLATES
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PTERYGOID PROCESS
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SPHENOID SPINE, LEFT
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STYLOID PROCESS
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ZYGOMATIC BONE
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Articular tubercle
(at anterior root of zygomatic arch)
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LEVEL-4
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Basiocciput (posterior clivus)
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Hypoglossal canal
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Pterygopalatine fossa
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Pterygoid plates
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Pterygoid process
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Occipitomastoid suture
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Occipital bone (squamous part)
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Pterygomaxillary fissure
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Sphenoid, greater wing
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Sphenoid spine
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Sphenopalatine foramen
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Styloid process, base
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Zygomatic arch
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Zygomaticofacial foramen / canal
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LEVEL-5
124
Foramen ovale
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Foramen spinosum
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Hyoglossal canal
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Inferior orbital fissure
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Occipital bone (squamous portion)
129
Occipitomastoid suture
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Pterygopalatine fossa
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Sphenoid, greater wing
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Sphenoid spine (right)
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Sphenopalatine foramen
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Sphenosquamous suture
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Temporal bone, tympanic
and petrous portions
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Tympanomastoid fissure
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LEVEL-6
138
Carotid canal
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Clivus –occipital part
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FORAMEN OVALE
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FORAMEN SPINOSUM
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FORAMEN LACERUM
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Sphenoid bone, greater wing
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HYPOGLOSSAL CANNAL
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INFERIOR ORBITAL FISSURE
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JUGULAR FORAMEN
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Occipital bone, squamous part
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OCCIPITOMASTOID SUTURE
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Petrooccipital fissure
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Petrosphenoidal fissure
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VIDIAN CANAL-Pterygoid canal
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Pterygopalatine fossa
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SPHENOID BONE BODY
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Sphenopalatine foramen
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Sphenosquamous suture
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PETROUS PART OF TEMPORAL BONE
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. Temporal bone, squamous part
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Temporal bone, tympanic part
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TYMPANO MASTOID FISSURE
160
LEVEL-7
161
CAROTID CANAL
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CLIVUS
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Foramen lacerum
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FORAMEN OVALE
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FORAMEN SPINOSUM
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Jugular foramen becoming sigmoid sinus
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INFERIOR ORBITAL FISSURE
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Jugular tubercle of occipital bone (roof of
hypoglossal canal)
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Occipital bone, squamous part
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Occipitomastoid suture
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Petroocipital fissure
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Petrosphenoidal fissure
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Pterygopalatine fossa
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BODY SPHENOID
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GREATER WING SPHENOID
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SPHENO SQUAMOUS SUTURE
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TYMPANO SQUAMOUS FISSURE
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PETROUS TEMPORAL
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TYMPANIC PART OF TEMPORAL
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SQUMOUS TEMPORAL
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LEVEL-8
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CAROTID CANAL
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FORAMEN ROTUNDUM
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JUGULAR TUBERCULE OF OCCIPITAL BONE
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MANDIBULAR FOSSA ROOF
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MIDDLE EAR
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SQUOMOS OCCIPUT
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OCCIPITO MASTOID SUTURE
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PETRO OCCIPITAL FISSURE
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SPHENOID BODY
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GREATER WING SPHENOID
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SPHENO SQUAMOUS SUTURE
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SPHENO ZYGOMATIC SUTURE
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PETROUS TEMPORAL
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SQUAMOUS TEMPORAL
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TYMPANIC TEMPORAL PART
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TYMPANOSQUAMOUS FISSURE
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LEVEL-9
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BASAL TURN OF COCHLEA
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Groove in body of sphenoid bone for internal
carotid artery
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MIDDLE EAR
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SQUOMOS OCCIPUT
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OCCIPITO MASTOID SUTURE
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Space connecting superior and inferior orbital
fissures
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BODY SPHENOID
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GREATER WING SPHENOID
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SPHENO SQUAMOUS SUTURE
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SPHENO ZYGOMATIC SUTURE
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TEMPORAL BONE, SQUAMOUS PART
210
LEVEL-10
211
COCHLEA
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INTERNAL AUDITORY CANAL
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MIDDLE EAR WITH MALLEUS AND INCUS
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SQUAMO OCCIPUT
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Occipitomastoid suture
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BODY SPHENOID
217
GREATER WING SPHENOID
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Space connecting superior and inferior orbital
fissures
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Sphenosquamous suture
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PETROUS TEMPORAL
221
LEVEL-11
222
Internal auditory canal
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Middle ear with malleus and incus
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SQUAMOUS OCCIPITO
225
OCCIPITO MASTOID SUTURE
226
BODY SPHENOID
227
GREATER WING SPHENOID
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Sphenosquamous suture
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PETROUS TEMPORAL
230
SUPERIOR ORBITAL FISSURE
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VESTIBULE WITH SEMICIRCULAR CANAL
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LEVEL-12
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SQUAMO- OCCIPITO
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OCCIPITO MASTOID SUTURE
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POSTERIOR SEMICIRCULAR CANAL
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BODY SPHENOID
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GREATER WING SPHENOID
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SPHENOSQUAMOUS SUTURE
239
PETROUS TEMPORAL
240

#Skull base radiology FOR #RADIATION ONCOLOGISTS